Lanthanide-Loaded Erythrocytes As Highly Sensitive Chemical Exchange Saturation Transfer MRI Contrast Agents

2013 ◽  
Vol 136 (2) ◽  
pp. 638-641 ◽  
Author(s):  
Giuseppe Ferrauto ◽  
Daniela Delli Castelli ◽  
Enza Di Gregorio ◽  
Sander Langereis ◽  
Dirk Burdinski ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Chemical Exchange ◽  
Mri Contrast Agents ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Mri Contrast ◽  
Highly Sensitive

Carbon Dots as a New Class of Diamagnetic Chemical Exchange Saturation Transfer (diaCEST) MRI Contrast Agents

2019 ◽  
Vol 131 (29) ◽  
pp. 9976-9980
Author(s):  
Jia Zhang ◽  
Yue Yuan ◽  
Minling Gao ◽  
Zheng Han ◽  
Chengyan Chu ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Carbon Dots ◽  
Chemical Exchange ◽  
Mri Contrast Agents ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Mri Contrast ◽  
New Class

Toward inert paramagnetic Ni(ii)-based chemical exchange saturation transfer MRI agents

2017 ◽  
Vol 46 (43) ◽  
pp. 15095-15106 ◽  
Author(s):  
Laura Caneda-Martínez ◽  
Laura Valencia ◽  
Isabel Fernández-Pérez ◽  
Martín Regueiro-Figueroa ◽  
Goran Angelovski ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Chemical Exchange ◽  
Mri Contrast Agents ◽  
Transfer Mechanism ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Mri Contrast

Rigid Ni(ii) complexes containing picolinamide groups show potential as MRI contrast agents operating through the chemical exchange saturation transfer mechanism.

Complexes of selected late period lanthanide(III) cations with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl ligands — A new platform for the development of paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents

2013 ◽  
Vol 91 (3) ◽  
pp. 211-219 ◽  
Author(s):  
Adam A.H. Elmehriki ◽  
Mark Milne ◽  
Mojmír Suchý ◽  
Robert Bartha ◽  
Robert H.E. Hudson
Keyword(s):  
Magnetic Resonance Imaging ◽  
Chemical Exchange ◽  
Acid Amide ◽  
Mri Contrast Agents ◽  
Chemical Exchange Saturation Transfer ◽  
Tetraacetic Acid ◽  
Saturation Transfer ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

A series of 18 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl derived complexes with selected late lanthanide(III) cations (Dy3+, Tb3+, and Tm3+) has been synthesized; their magnetic properties have been evaluated and compared to those derived from DOTAM. Peralkylation of cyclen with corresponding N-iodoacetyl amines was utilized as the key step in the synthesis. Chemical exchange saturation transfer (CEST) spectra of the complexes have been acquired at 37 °C, revealing that Tm3+-derived DOTAM-alkyl complexes possess the most favorable properties as potential paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents.

Chapter 3. Chemical Exchange Saturation Transfer (CEST) Contrast Agents

2017 ◽  
pp. 243-317 ◽  
Author(s):  
Giuseppe Ferrauto ◽  
Silvio Aime ◽  
Michael T. McMahon ◽  
Janet R. Morrow ◽  
Eric M. Snyder ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer

Tetrakis-(N-methyl-4-pyridinium)-porphyrin as a diamagnetic chemical exchange saturation transfer (diaCEST) MRI contrast agent

2021 ◽  
Author(s):  
Subhayan Chakraborty ◽  
Mainak Das ◽  
A. Srinivasan ◽  
Arindam Ghosh
Keyword(s):  
Contrast Agent ◽  
Chemical Exchange ◽  
Mri Contrast Agent ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Mri Contrast ◽  
Wide Range ◽  
Good Contrast

Easily synthesizable tetrakis-(N-methyl-4-pyridinium)-porphyrin as a diaCEST agent that shows nearly pH independent good contrast in a wide range of pH.

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