Tetrakis-(N-methyl-4-pyridinium)-porphyrin as a diamagnetic chemical exchange saturation transfer (diaCEST) MRI contrast agent

2021 ◽  
Author(s):  
Subhayan Chakraborty ◽  
Mainak Das ◽  
A. Srinivasan ◽  
Arindam Ghosh

Easily synthesizable tetrakis-(N-methyl-4-pyridinium)-porphyrin as a diaCEST agent that shows nearly pH independent good contrast in a wide range of pH.

2013 ◽  
Vol 136 (2) ◽  
pp. 638-641 ◽  
Author(s):  
Giuseppe Ferrauto ◽  
Daniela Delli Castelli ◽  
Enza Di Gregorio ◽  
Sander Langereis ◽  
Dirk Burdinski ◽  
...  

NeuroImage ◽  
2018 ◽  
Vol 179 ◽  
pp. 144-155 ◽  
Author(s):  
Moritz Zaiss ◽  
Mark Schuppert ◽  
Anagha Deshmane ◽  
Kai Herz ◽  
Philipp Ehses ◽  
...  

1988 ◽  
Vol 29 (5) ◽  
pp. 599-602 ◽  
Author(s):  
M. Lönnemark ◽  
A. Hemmingsson ◽  
J. Carlsten ◽  
A. Ericsson ◽  
E. Holtz ◽  
...  

Non-biodegradable superparamagnetic particles containing magnetite were evaluated as a potential contrast agent for the gastrointestinal tract. The particles were administered to pigs perorally either suspended in water or mixed with food. The gastrointestinal tract structures were excellently depicted through a lowered signal intensity of their content in both T1 and T2 weighted images. Relatively large volumes with low particle concentration seemed to give a good contrast agent distribution, especially when the administration was extended over a period of time. Problems with artefacts and blurring in the images caused by a too high local concentration of the contrast agent should also be minimized by using low particle concentrations.


2019 ◽  
Vol 131 (29) ◽  
pp. 9976-9980
Author(s):  
Jia Zhang ◽  
Yue Yuan ◽  
Minling Gao ◽  
Zheng Han ◽  
Chengyan Chu ◽  
...  

2011 ◽  
Vol 66 (6) ◽  
pp. 1697-1703 ◽  
Author(s):  
Todd C. Soesbe ◽  
Matthew E. Merritt ◽  
Kayla N. Green ◽  
Federico A. Rojas-Quijano ◽  
A. Dean Sherry

2017 ◽  
Vol 46 (43) ◽  
pp. 15095-15106 ◽  
Author(s):  
Laura Caneda-Martínez ◽  
Laura Valencia ◽  
Isabel Fernández-Pérez ◽  
Martín Regueiro-Figueroa ◽  
Goran Angelovski ◽  
...  

Rigid Ni(ii) complexes containing picolinamide groups show potential as MRI contrast agents operating through the chemical exchange saturation transfer mechanism.


2015 ◽  
Vol 51 (23) ◽  
pp. 4869-4871 ◽  
Author(s):  
Amnon Bar-Shir ◽  
Yajie Liang ◽  
Kannie W. Y. Chan ◽  
Assaf A. Gilad ◽  
Jeff W. M. Bulte

Superpositively charged GFP mutants demonstrate dramatically improved chemical exchange saturation transfer (CEST) MRI contrast compared to their wild type counterparts.


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