Spiroketal Formation and Modification in Avermectin Biosynthesis Involves a Dual Activity of AveC

2013 ◽  
Vol 135 (4) ◽  
pp. 1540-1548 ◽  
Author(s):  
Peng Sun ◽  
Qunfei Zhao ◽  
Futao Yu ◽  
Hua Zhang ◽  
Zhuhua Wu ◽  
...  
Keyword(s):  
Avermectin Biosynthesis

Avermectin biosynthesis. Intact incorporation of a diketide chain-assembly intermediate into the polyketide macrocyclic ring

1994 ◽  
Vol 35 (2) ◽  
pp. 327-330 ◽  
Author(s):  
Christopher J. Dutton ◽  
Antony M. Hooper ◽  
Peter F. Leadlay ◽  
James Staunton
Keyword(s):  
Macrocyclic Ring ◽  
Avermectin Biosynthesis ◽  
Assembly Intermediate

RAPD Analysis on Avermectin High-Producing Strain of Streptomyces Avermilis Irradiated by 12C6+ Ions

2011 ◽  
Vol 339 ◽  
pp. 701-704 ◽  
Author(s):  
Yong Heng Bo ◽  
Shu Yang Wang ◽  
Ji Hong Chen ◽  
Jian Ping Liang
Keyword(s):  
Random Amplified Polymorphic Dna ◽  
Genetic Material ◽  
Similarity Index ◽  
Heavy Ion ◽  
Streptomyces Avermitilis ◽  
Original Strain ◽  
Ion Accelerator ◽  
Modern Physics ◽  
Avermectin Biosynthesis ◽  
Academy Of Sciences

Italic textAbstract. Industrial Streptomyces avermitilis were irradiated by 80 MeV/u 12C6+ ions whith were provided by the Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou Heavy Ion Accelerator. The high titers of mutants were obtained with different doses. The original strains and the high titers of mutants were detected and analyzed by Random Amplified Polymorphic DNA technology (RAPD). The results show that bands could be got from amplify the original strain by 4 primers of 28 primers and the high titers of mutants were amplified by the 4 primers. The amplified products were analysed by Jaccard formula. After 10 Gy, 30 Gy, 40 Gy, 45 Gy, 50 Gy, 70 Gy isodose irradiation, the similarity index were 0.63, 0.75, 0.71, 0.8, 0.61, 0.73. It was confirmed that at the DNA level, not only the high titers strains and the original mutant strain’s DNA were different, but also the high titers of the different mutants’ DNA were different. Therefore, ion implantation method changed the different Streptomyces avermitilis genetic material which promote the importance trace of avermectin biosynthesis changed, and different high titers of Streptomyces avermitilis were obtained.

Avermectin Biosynthesis

1997 ◽  
Vol 97 (7) ◽  
pp. 2591-2610 ◽  
Author(s):  
Haruo Ikeda ◽  
Satoshi Ōmura
Keyword(s):  
Avermectin Biosynthesis

ChemInform Abstract: Avermectin Biosynthesis

ChemInform ◽  
2010 ◽  
Vol 29 (6) ◽  
pp. no-no
Author(s):  
H. IKEDA ◽  
S. OMURA
Keyword(s):  
Avermectin Biosynthesis
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