scholarly journals SAV742, a Novel AraC-Family Regulator from Streptomyces avermitilis, Controls Avermectin Biosynthesis, Cell Growth and Development

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Di Sun ◽  
Jianya Zhu ◽  
Zhi Chen ◽  
Jilun Li ◽  
Ying Wen
Keyword(s):  
Cell Growth ◽  
Growth And Development ◽  
Streptomyces Avermitilis ◽  
Avermectin Biosynthesis ◽  
Arac Family

Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma

2003 ◽  
Vol 33 (8) ◽  
pp. 2223-2232 ◽  
Author(s):  
Jeffrey C. Rathmell ◽  
Rebecca L. Elstrom ◽  
Ryan M. Cinalli ◽  
Craig B. Thompson
Keyword(s):  
T Cell ◽  
Cell Growth ◽  
Cell Size ◽  
Growth And Development ◽  
T Cell Growth

GENERATIVE CYCLES OF PROTEIN AND TRANSAMINASE IN THE GROWING CORN RADICLE

1959 ◽  
Vol 37 (4) ◽  
pp. 621-639 ◽  
Author(s):  
F. S. Cook
Keyword(s):  
Enzyme Activity ◽  
Cell Growth ◽  
Growth And Development ◽  
Specific Protein ◽  
Soluble Nitrogen ◽  
Transaminase Activity ◽  
Cell Numbers ◽  
Nitrogen Levels ◽  
Linear Distance ◽  
Cellular Development

Measurements have been made of growth rates, cell numbers, fresh and dry weights, protein and soluble nitrogen levels, and glutamic–aspartic transaminase activity in six successive 2 mm segments of the radicles of 3-day-old corn seedlings. The measured quantities of protein and enzyme activity are related to the stage of average cellular development, to a linear distance scale along the axis of the radicle, and to the time scale. Increments per cell per hour during cell growth are therefore computed. An attempt is made to explain the significance of the genesis of the transaminase in the growth and development of the radicle cells, to the concurrent genesis of total and specific protein, and to other generative cycles.

Interferons in cell growth and development

1989 ◽  
Vol 5 ◽  
pp. 19-24 ◽  
Author(s):  
Giovanna Romeo ◽  
Gianna Fiorucci ◽  
Giovanni B. Rossi
Keyword(s):  
Cell Growth ◽  
Growth And Development

Many models for cell growth and development

Nature ◽  
1975 ◽  
Vol 257 (5526) ◽  
pp. 448-449
Author(s):  
Robert Shields
Keyword(s):  
Cell Growth ◽  
Growth And Development

RAPD Analysis on Avermectin High-Producing Strain of Streptomyces Avermilis Irradiated by 12C6+ Ions

2011 ◽  
Vol 339 ◽  
pp. 701-704 ◽  
Author(s):  
Yong Heng Bo ◽  
Shu Yang Wang ◽  
Ji Hong Chen ◽  
Jian Ping Liang
Keyword(s):  
Random Amplified Polymorphic Dna ◽  
Genetic Material ◽  
Similarity Index ◽  
Heavy Ion ◽  
Streptomyces Avermitilis ◽  
Original Strain ◽  
Ion Accelerator ◽  
Modern Physics ◽  
Avermectin Biosynthesis ◽  
Academy Of Sciences

Italic textAbstract. Industrial Streptomyces avermitilis were irradiated by 80 MeV/u 12C6+ ions whith were provided by the Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou Heavy Ion Accelerator. The high titers of mutants were obtained with different doses. The original strains and the high titers of mutants were detected and analyzed by Random Amplified Polymorphic DNA technology (RAPD). The results show that bands could be got from amplify the original strain by 4 primers of 28 primers and the high titers of mutants were amplified by the 4 primers. The amplified products were analysed by Jaccard formula. After 10 Gy, 30 Gy, 40 Gy, 45 Gy, 50 Gy, 70 Gy isodose irradiation, the similarity index were 0.63, 0.75, 0.71, 0.8, 0.61, 0.73. It was confirmed that at the DNA level, not only the high titers strains and the original mutant strain’s DNA were different, but also the high titers of the different mutants’ DNA were different. Therefore, ion implantation method changed the different Streptomyces avermitilis genetic material which promote the importance trace of avermectin biosynthesis changed, and different high titers of Streptomyces avermitilis were obtained.

scholarly journals Improvement Activity of 1-Deoxynojirimycin in the Growth of Dairy Goat Primary Mammary Epithelial Cell through Upregulating LEF-1 Expression

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Shengyue Ji ◽  
Ming Liu ◽  
Yuping Zhang ◽  
Hongfu Zhang
Keyword(s):  
Mammary Gland ◽  
Cell Growth ◽  
Epithelial Cell ◽  
Growth And Development ◽  
Mrna Level ◽  
Dairy Goat ◽  
Breast Epithelial Cell ◽  
Mrna Levels ◽  
Dairy Goats ◽  
Breast Epithelial

LEF-1/wnt10b is one of the most important signaling pathways regulating mammary gland growth and development and is also a potential target for molecular breeding. In this work, 1-deoxynojirimycin (DNJ), a natural alkaloid extracted from plant mulberry or microorganism, was found to have a positive activity in primary breast epithelial cell growth of dairy goats. The findings showed that, compared to the control, 6 μM DNJ in the DMEM/F12 medium in vitro greatly improved the density of dairy goat breast epithelial cell and significantly increased the LEF-1 mRNA level (P<0.01) and thus enhanced cell growth. In addition, DNJ displayed a similar function in alleviating the growth suppression of epithelial cell and the decrease of LEF-1 mRNA level resulting from lentiviral-mediated LEF-1 knockdown. Simultaneously, no significant change of the mRNA levels of IGF-1 and Fgf10, the other two key regulators in mammary gland growth and development, could be detected. Furthermore, the mammary duct of DNJ-fed mouse illustrated a better development accompanied with a higher LET-1 mRNA level than that of the control. In conclusion, DNJ could improve breast epithelial cell growth through upregulating LEF-1 expression, which supplied a new means in studying mammary gland growth and development.

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