Analogues of Vaccinia Virus DNA Topoisomerase I Modified at the Active Site Tyrosine

2005 ◽  
Vol 127 (10) ◽  
pp. 3321-3331 ◽  
Author(s):  
Rong Gao ◽  
Yi Zhang ◽  
Ambar K. Choudhury ◽  
Larisa M. Dedkova ◽  
Sidney M. Hecht
Keyword(s):  
Vaccinia Virus ◽  
Active Site ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Active Site Tyrosine

Effects of Modification of the Active Site Tyrosine of Human DNA Topoisomerase I†

Biochemistry ◽  
2006 ◽  
Vol 45 (27) ◽  
pp. 8402-8410 ◽  
Author(s):  
Rong Gao ◽  
Yi Zhang ◽  
Larisa Dedkova ◽  
Ambar K. Choudhury ◽  
Nicolas J. Rahier ◽  
...  
Keyword(s):  
Active Site ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Human Dna ◽  
Active Site Tyrosine ◽  
Human Dna Topoisomerase I

scholarly journals Active Site Mutations in DNA Topoisomerase I Distinguish the Cytotoxic Activities of Camptothecin and the Indolocarbazole, Rebeccamycin

2001 ◽  
Vol 277 (6) ◽  
pp. 3813-3822 ◽  
Author(s):  
Michael H. Woo ◽  
John R. Vance ◽  
Ana R. Otero Marcos ◽  
Christian Bailly ◽  
Mary-Ann Bjornsti
Keyword(s):  
Active Site ◽  
Topoisomerase I ◽  
Cytotoxic Activities ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Active Site Mutations
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