The Influence of a Quaternary Ammonium Group on the Hydrogen Atoms of an Adjacent Methylene Group

1933 ◽  
Vol 55 (12) ◽  
pp. 5000-5002 ◽  
Author(s):  
Arnold O. Jackson ◽  
C. S. Marvel
Keyword(s):  
Quaternary Ammonium ◽  
Hydrogen Atoms ◽  
Ammonium Group ◽  
Quaternary Ammonium Group ◽  
Methylene Group ◽  
Adjacent Methylene

A Highly Active Aqueous Olefin Metathesis Catalyst Bearing a Quaternary Ammonium Group

ChemSusChem ◽  
2008 ◽  
Vol 1 (1-2) ◽  
pp. 103-109 ◽  
Author(s):  
Łukasz Gułajski ◽  
Anna Michrowska ◽  
Joanna Narożnik ◽  
Zuzanna Kaczmarska ◽  
Leszek Rupnicki ◽  
...  
Keyword(s):  
Quaternary Ammonium ◽  
Olefin Metathesis ◽  
Ammonium Group ◽  
Highly Active ◽  
Metathesis Catalyst ◽  
Quaternary Ammonium Group

scholarly journals A biocompatible betaine-functionalized polycation for coacervation

Soft Matter ◽  
2018 ◽  
Vol 14 (3) ◽  
pp. 387-395 ◽  
Author(s):  
Mintai P. Hwang ◽  
Xiaochu Ding ◽  
Jin Gao ◽  
Abhinav P. Acharya ◽  
Steven R. Little ◽  
...  
Keyword(s):  
Amino Acid ◽  
Quaternary Ammonium ◽  
Bacterial Activity ◽  
Complex Coacervation ◽  
Ammonium Group ◽  
Naturally Occurring ◽  
Quaternary Ammonium Group

Betaine, a naturally occurring amino acid, is conjugated onto a polyester backbone, in which the quaternary ammonium group imparts additional functionality to the resulting polycation (B-PED). B-PED demonstrates excellentin vitroandin vivobiocompatibility and is also assessed for its effect on angiogenesis, anti-bacterial activity, and complex coacervation.

Structure Investigations of Agonists of the Natural Neurotransmitter Acetylcholine II [1]. X-ray Structure Analysis of Trimethyl(4-oxopentyl)ammonium-chloride

1982 ◽  
Vol 37 (3-4) ◽  
pp. 282-288 ◽  
Author(s):  
Gieren Gieren ◽  
Michail Kokkinidis
Keyword(s):  
Crystal Structure ◽  
Ammonium Chloride ◽  
Structure Analysis ◽  
Quaternary Ammonium ◽  
Fourier Synthesis ◽  
Orthorhombic Space Group ◽  
X Ray ◽  
Ammonium Group ◽  
Significant Difference ◽  
Quaternary Ammonium Group

Abstract The crystal structure of Trimethyl(4-oxopentyl)ammonium-chloride ([(CH3)3N+-(CH2)3COCH3]Cl-) (1) was determined by an X-ray structure analysis. 1 crystallizes in the orthorhombic space group P212121 with a = 10.440 (3), b = 14.600 (9), c = 6.804 (9) Å and with four formula units per unit cell. The structure was solved by a Patterson and a successive Fourier synthesis. The least squares refinement yielded an R-value of 0.064 for 1077 observed reflections. The cation of 1 is derived from acetylcholine by replacement of the ester oxygen with a CH2 group. It shows a potent nicotinic activity and a significant difference in conformation as compared with acetylcholine. In the crystal structure the anions are oriented stereospecifically with respect to the tetrahedron of the quaternary ammonium group. The geometry of two triangles formed by the quaternary nitrogen atom, the oxygen atom of the carbonyl group, and by either of the two anions nearest to the quaternary ammonium group is characteristic for the nicotinic activity of 1.

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