Additions and Corrections-The Bitter Principle ofHelenium Tenuifolium

1949 ◽  
Vol 71 (12) ◽  
pp. 4163-4163
Author(s):  
Herbert E. Ungnade ◽  
Edward C. Hendley
Keyword(s):  
Bitter Principle

scholarly journals On the Structure of the Bitter Principle of Ilex oldhami Miq., Ilex pedunculosa Miq. and Ilex rotunda Thumb.

1973 ◽  
pp. 778-785 ◽  
Author(s):  
Tsunao HASE ◽  
Hidehiko HAGII ◽  
Michiko ISHIZU ◽  
Masamitsu OCHI ◽  
Nobutaka ICHIKAWA ◽  
...  
Keyword(s):  
Bitter Principle ◽  
Ilex Rotunda

Bitter Principle Drugs

1984 ◽  
pp. 125-143 ◽  
Author(s):  
Hildebert Wagner ◽  
Sabine Bladt ◽  
Eva Maria Zgainski
Keyword(s):  
Bitter Principle

scholarly journals Estimation of Amarogentin content and standardization of different samples of Chirata collected from crude drug markets of Nepal

2021 ◽  
Vol 2 (1) ◽  
pp. 1-11
Author(s):  
Bishun Dayal Prasad Patel ◽  
Shyam Babu Yadav ◽  
Shiv Mangal Prasad ◽  
Kanti Shrestha ◽  
Narendranath Tiwari ◽  
...  
Keyword(s):  
Moisture Content ◽  
Chemical Constituent ◽  
Local Market ◽  
Foreign Matter ◽  
Swertia Chirayita ◽  
Bitter Principle ◽  
Main Indicator ◽  
Pharmaceutical Industries ◽  
Major Chemical ◽  
Over Exploitation

Background: Amarogentin is a major chemical constituent of bitter principle found in Swertia chirayita (Roxb.ex Fleming) Karsten; family Gentianaceae. Chirata is an endangered species because of it’s over exploitation for pharmaceutical industries. These species are mainly found in the Himalayas and used for gastritis, diabetes, jaundice, urinary disorders, liver disorders, etc. The bitter principle as a main indicator of the medical herb, Nowadays, other species of Swertia are substituted and traded by the name of Chirata. Therefore, the present study was undertaken to estimate Amarogentin and to standardize Chirata samples collected from different markets of Nepal in 2013 A.D. Method and Materials: Different market samples of the species were analyzed for foreign matter, moisture content, extractive values; and bitter principles i.e. Amarogentin by using UFLC at Pacific Analytical Laboratory and Training Center, Lalitpur, Nepal. Result: The findings revealed that foreign matter, moisture content, extractive values; and bitter principles i.e. Amarogentin content varied with different market samples. Methonolic extraction yielded higher percentage of extracts than that of chloroform extraction. Samples including more root and stem, in general, contained higher Amarogentin than samples containing more leaves. The samples containing higher moisture content were lesser in Amarogentin content. The finding of Amarogentin of sample collected from Charikot, Dolkha was 3mg/100gm.Conclusion: In this study, the findings suggest that sample collected from local market of Charikot, Dolkha district was Swertia chirayita and was the best quality.

scholarly journals Degradative Studies in the Picrotoxinin Series

2021 ◽  
Author(s):  
◽  
Raymond Maurice Carman
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
High Oxygen Content ◽  
East Indies ◽  
Central Nervous System Stimulant ◽  
Bitter Principle ◽  
Elementary Analysis ◽  
Fish Poison ◽  
Barbiturate Poisoning ◽  
Convulsant Drug

<p>PICROTOXIN is a bitter principle of the berries of the species Mensiperum coculus and Anamirata coculus, creepers which are indigenous to the East Indies. It was first isolated in 1812, and subsequent elementary analysis showed that it contained only carbon, hydrogen, and oxygen. Because of its potent poisonous nature and its physiological action, together with its high oxygen content, picrotoxin has often been referred to as an “oxygen alkaloid”. It is a central nervous system stimulant and a powerful convulsant drug. It is used in medicine as an antidote to barbiturate poisoning, being still preferred for this purpose over many other drugs. It has also been used in cases of alcoholic intoxication, and as a fish poison.</p>

Radioimmunoassay for the Citrus Bitter Principle, Naringin, and Related Flavonoid-7-O-neohesperidosides

Planta Medica ◽  
1982 ◽  
Vol 44 (02) ◽  
pp. 82-86 ◽  
Author(s):  
P. Jourdan ◽  
R. Mansell ◽  
E. Weiler
Keyword(s):  
Bitter Principle

TERPENOIDS: XII. THE STRUCTURE OF CHAPARRIN

1965 ◽  
Vol 43 (11) ◽  
pp. 2996-3007 ◽  
Author(s):  
T. A. Davidson ◽  
T. R. Hollands ◽  
P. De Mayo ◽  
M. Nisbet
Keyword(s):  
Bitter Principle ◽  
Two Stages

Chaparrin, the bitter principle from Castela nicholsonii may be dehydrated in two stages to give the partially aromatized substance chaparrol. By further stepwise degradation the latter has been converted to the dihydrophenanthrene (XIII) which allows the assignment of structures XVII and I to chaparrol and chaparrin respectively.

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