Molecular recognition between oligopeptides and nucleic acids: sequence-specific binding of the naturally occurring antibiotic (4S)-(+)-anthelvencin A and its (4R)-(-) enantiomer to deoxyribonucleic acids deduced from proton NMR, footprinting, and thermodynamic data

1989 ◽  
Vol 111 (1) ◽  
pp. 345-354 ◽  
Author(s):  
Moses Lee ◽  
Regan G. Shea ◽  
John A. Hartley ◽  
Koren Kissinger ◽  
Richard T. Pon ◽  
...  
Soft Matter ◽  
2015 ◽  
Vol 11 (10) ◽  
pp. 1973-1990 ◽  
Author(s):  
Marianna Yanez Arteta ◽  
Debora Berti ◽  
Costanza Montis ◽  
Richard A. Campbell ◽  
Caroline Eriksson ◽  
...  

Molecular recognition of nucleic acids by dendrimers with non-covalently attached nucleolipids can be tuned by nucleolipid type and order of addition.


2016 ◽  
Vol 60 (1) ◽  
pp. 27-35 ◽  
Author(s):  
Pawan Jolly ◽  
Pedro Estrela ◽  
Michael Ladomery

There are an increasing number of applications that have been developed for oligonucleotide-based biosensing systems in genetics and biomedicine. Oligonucleotide-based biosensors are those where the probe to capture the analyte is a strand of deoxyribonucleic acid (DNA), ribonucleic acid (RNA) or a synthetic analogue of naturally occurring nucleic acids. This review will shed light on various types of nucleic acids such as DNA and RNA (particularly microRNAs), their role and their application in biosensing. It will also cover DNA/RNA aptamers, which can be used as bioreceptors for a wide range of targets such as proteins, small molecules, bacteria and even cells. It will also highlight how the invention of synthetic oligonucleotides such as peptide nucleic acid (PNA) or locked nucleic acid (LNA) has pushed the limits of molecular biology and biosensor development to new perspectives. These technologies are very promising albeit still in need of development in order to bridge the gap between the laboratory-based status and the reality of biomedical applications.


1990 ◽  
Vol 3 (1) ◽  
pp. 26-35 ◽  
Author(s):  
Christian Bailly ◽  
Nicole Helbecque ◽  
Jean-Pierre Hénichart ◽  
Pierre Colson ◽  
Claude Houssier ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document