Preparation of anhydrous pyridine hydrochloride

1955 ◽  
Vol 32 (1) ◽  
pp. 39 ◽  
Author(s):  
Moddie D. Taylor ◽  
Louis R. Grant
1989 ◽  
Vol 54 (1) ◽  
pp. 225-228 ◽  
Author(s):  
Irena Červená ◽  
Jiří Holubek ◽  
Emil Svátek ◽  
Jan Metyš ◽  
Martin Valchář ◽  
...  

Heating of 4-methoxydibenzo[b,e]thiepin-11(6H)-one with pyridine hydrochloride to 225 to 235 °C effected demethylation and gave IV. Its sodium salt reacted with 3-dimethylaminopropyl chloride in ethanol and afforded the 4-(3-dimethylaminopropoxy) compound II. The isomeric ether III was prepared via the 4-(4-bromobutoxy) compound V. Hydrochloride of II (VÚFB-17 033) inhibited mildly the binding of [3H]desipramine in rat hypothalamus, had antireserpine activity in rats, mild anticonvulsant effect, and antihypoxic effect in the test of nitrogen anoxia in mice.


2001 ◽  
Vol 40 (17) ◽  
pp. 4428-4435 ◽  
Author(s):  
Christelle Rivière ◽  
Martine Nierlich ◽  
Michel Ephritikhine ◽  
Charles Madic

2020 ◽  
Vol 7 (21) ◽  
pp. 3474-3479
Author(s):  
Shiwen Liu ◽  
Lili Wang ◽  
Zhipeng Ma ◽  
Xiaojun Zeng ◽  
Bo Xu

Divergent synthesis of allyl and vinyl sulfides by a Py-HCl catalyzed tandem thiolation–elimination reaction between N-thiosuccinimides and alkenes.


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