Comment on "The Extent of the Relationship between the Graph-Theoretical and the Geometric Shape Coefficients of Chemical Compounds"

1995 ◽  
Vol 35 (6) ◽  
pp. 1081-1081
Author(s):  
Michel Petitjean
Keyword(s):  
Chemical Compounds ◽  
Geometric Shape ◽  
The Relationship

scholarly journals Pharmaceutical properties of 'sucupira' (Pterodon spp.)

2010 ◽  
Vol 46 (4) ◽  
pp. 607-616 ◽  
Author(s):  
Daiane Hansen ◽  
Mitsue Haraguchi ◽  
Antonio Alonso
Keyword(s):  
Biological Effects ◽  
Chemical Compounds ◽  
Experimental Models ◽  
Popular Medicine ◽  
Isolation And Characterization ◽  
Pharmaceutical Properties ◽  
The Relationship

The plant of the genus Pterodon (Fabaceae, Leguminosae), commonly known as 'sucupira' or 'faveira', are disseminated throughout the central region of Brazil and has frequently been used in popular medicine for its anti-rheumatic, analgesic, and anti-inflammatory properties. In recent years, interest in these plants has increased considerably. The biological effects of different phytoextracts and pure metabolites have been investigated in several experimental models in vivo and in vitro. The literature describes flavonoids, triterpene and steroids, while one paper presented studies with proteins isolated from the genus. This review provides an overview of phytochemical and pharmacological research in Pterodon, showing the main chemical compounds studied to date, and focusing on the relationship between these molecules and their biological activity. Furthermore, this study paves the way for more in-depth investigation, isolation and characterization of the molecules of this plant genus.

scholarly journals Numerical Analysis and Experimental Study on Fabrication of High Aspect Ratio Tapered Ultrafine Holes by Over-Growth Electroforming Process

Micromachines ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 824
Author(s):  
Yunyan Zhang ◽  
Pingmei Ming ◽  
Runqing Li ◽  
Ge Qin ◽  
Xinmin Zhang ◽  
...  
Keyword(s):  
Aspect Ratio ◽  
High Aspect Ratio ◽  
Structural Parameters ◽  
Geometric Shape ◽  
High Tech ◽  
Shape Evolution ◽  
Metallic Plate ◽  
Electroforming Process ◽  
Photoresist Film ◽  
The Relationship

High aspect ratio (HAR) ultrafine tapered holes (diameter ≤5 μm; AR ≥5) are the most important elements for some high-tech perforated metallic products, but they are very difficult to manufacture. Therefore, this paper proposes a nontraditional over-growth electroforming process. The formation mechanism of the HAR ultrafine tapered holes is investigated, and the factors controlling the geometric shape evolution are analyzed numerically. It was found that the geometric shape and dimensions of the holes are highly dependent on the diameter and thickness of the photoresist film patterns, but are hardly affected by the spacing between two neighboring patterns; the achievable diameter for a given hole depth becomes small with the increasing pattern diameter, but it becomes big with the increasing pattern thickness. These correlations can be well interpreted by the established two empirical equations that characterize the relationship between the minimum orifice of the tapered hole and the structural parameters of the photoresist film patterns previously formed on the substrate. Application of the fabricated 1500 tapered holes with 3-μm diameter and 17-AR as the nozzles of the medical precision nebulizer is also examined. The studies show that the over-growth electroforming process is highly applicable in fabricating the perforated metallic plate with HAR ultrafine tapered holes.

scholarly journals Experimental research of the process of shock pulse transformation through biological objects of fixed geometric shape

1970 ◽  
pp. 30-35
Author(s):  
V Yakovlev
Keyword(s):  
Raw Materials ◽  
Experimental Studies ◽  
Geometric Shape ◽  
Agricultural Products ◽  
Successful Implementation ◽  
Biological Objects ◽  
Quantitative Characteristics ◽  
The Relationship ◽  
Qualitative Characteristics ◽  
Qualitative And Quantitative Characteristics

Successful implementation of agricultural products requires compliance with the requirements of standards to ensure its high quality, ensuring the technological process (production, processing, storage) with a sufficient level of quality characteristics of the initial raw materials, product quality control at intermediate and final operations. Such qualitative characteristics of products, particularly a fixed geometric shape, the degree of ripeness, presence and depth of the damage, it is not always possible to determine the external condition of the product (e.g., melons) without its destruction. To assess the qualitative and quantitative characteristics of agricultural products, various physical methods are used, of which a special place is occupied by the method of acoustic sensing, which consists in the fact that the properties of products (as biological objects) that determine the excitation and propagation of elastic vibrations are closely related to their anatomical structure and physical and biochemical characteristics, which in turn change during their vegetation when reaching the appropriate degree of ripeness. This material presents the results of experimental studies to establish the relationship between the parameters of the aftereffect of shock excitation of biological objects of plant origin of a fixed geometric shape with their qualitative characteristics, to determine the characteristics and their quantitative values, which in turn makes it possible to implement technical devices Express nondestructive control of qualitative characteristics of agricultural products.

scholarly journals Simultaneous Determination of Nine Active Compounds of the Traditional Chinese Medicinal Prescription Shaoyao-Gancao-Tang and Analysis of the Relationship between Therapeutical Effect and Compatibility of Medicines

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Guangwei Zhu ◽  
Guijun Zhang ◽  
Meng Wang ◽  
Jingjuan Wang ◽  
Weixin Zeng ◽  
...  
Keyword(s):  
Quality Control ◽  
Simultaneous Determination ◽  
Flow Rate ◽  
Glycyrrhizic Acid ◽  
Detection Method ◽  
Chemical Compounds ◽  
Active Compounds ◽  
Column Temperature ◽  
The Relationship

A simple and sensitive HPLC-DAD detection method was established for the simultaneous determination of nine compounds including oxypaeoniflorin, albiflorin, paeoniflorin, benzoylpaeoniflorin, glycyrrhizic acid, liquiritin, isoliquiritin, liquiritigenin, and isoliquiritigenin in the Traditional Chinese Medicinal Prescription Shaoyao-Gancao-Tang (SGT) and we analyze the relationship between therapeutical effect and compatibility of medicines by using an Agilent extend-C18 column at a flow rate of 1 mL/min. The column temperature was maintained at 30°C and the detection wavelength was set at 230 nm for oxypaeoniflorin, albiflorin, paeoniflorin, benzoylpaeoniflorin, and glycyrrhizic acid; 276 nm for liquiritin and liquiritigenin; 360 nm for isoliquiritin and isoliquiritigenin. The total contents of the nine compounds in SGT varied from 4.65 to 20.06 mg/mL. The results of this study showed that the content of chemical compounds of Traditional Chinese Medicinal Prescription is mainly influenced by the dosage and compatibility of medicines and the therapeutical effect of Traditional Chinese Medicinal prescription is mainly influenced by the dosage and compatibility of medicines. The method could be suitable for quality control of SGT with bioactive multicompounds.

scholarly journals STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS. II

1936 ◽  
Vol 64 (4) ◽  
pp. 625-639 ◽  
Author(s):  
K. Landsteiner ◽  
John Jacobs
Keyword(s):  
Anaphylactic Shock ◽  
Chemical Compounds ◽  
Skin Surface ◽  
Substituted Benzenes ◽  
Allergic Manifestation ◽  
Acyl Chlorides ◽  
Benzyl Chlorides ◽  
Simple Chemical ◽  
The One ◽  
The Relationship

In continuation of previous work sensitization experiments have been made with various substances such as urushiol, benzyl chlorides, and acyl chlorides. In the case of a series of substituted benzenes (Cl, NO2) a connection between sensitizing capacity and lability of the Cl or NO2 groups has been shown, indicating the formation of conjugated antigens in the animal. This led to the study of benzyl and acyl chlorides which, actually, were found to have sensitizing capacity. Most informative as to the relationship between reactions of the skin surface and anaphylaxis were experiments with acyl chlorides. Guinea pigs sensitized with p-chlorobenzoyl chloride showed, on the one hand, the usual surface lesions after application of the substance, and on the other typical anaphylactic shock following intravenous injection of a compound of p-chlorobenzoyl chloride and guinea pig serum; from which it may be inferred that the two types of allergic manifestation are closely related conditions.

scholarly journals STUDIES ON A SARCOSINE OXIDASE OF BACTERIAL ORIGIN

1950 ◽  
Vol 34 (1) ◽  
pp. 9-17 ◽  
Author(s):  
Paul H. Kopper ◽  
Keyword(s):  
Chemical Compounds ◽  
Enzyme Concentration ◽  
Order Reaction ◽  
Effect Of Temperature ◽  
Heat Inactivation ◽  
Sarcosine Oxidase ◽  
First Order ◽  
Optimal Activity ◽  
Relationship Of ◽  
The Relationship

A "sarcosine oxidase" was prepared from a creatinine-decomposing strain of Pseudomonas aeruginosa. The enzyme is inactivated by drying, lyophilization, and dialysis against distilled water. No dialyzable cofactor was found. Optimal activity of the enzyme is reached at pH 7.8. Enzyme activity is directly proportional to enzyme concentration and also to substrate concentration up to the point of saturation of enzyme with substrate molecules. One molecule of enzyme combines with one molecule of substrate. Data concerning the effect of temperature and of a variety of chemical compounds on the enzyme are presented. Its inactivation by heat follows the course of a first order reaction, and the critical thermal increment between 48° and 52°C. was calculated to be 103,000 calories per mol. The relationship of enzyme concentration to heat inactivation rates is illustrated.

scholarly journals The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 767
Author(s):  
Heather Armstrong ◽  
Michael Bording-Jorgensen ◽  
Eytan Wine
Keyword(s):  
Human Health ◽  
Chemical Compounds ◽  
Dietary Factors ◽  
Cancer Development ◽  
Future Research ◽  
Preventative Medicine ◽  
Prevention And Treatment ◽  
The Relationship ◽  
Common Misconceptions

Many studies performed to date have implicated select microbes and dietary factors in a variety of cancers, yet the complexity of both these diseases and the relationship between these factors has limited the ability to translate findings into therapies and preventative guidelines. Here we begin by discussing recently published studies relating to dietary factors, such as vitamins and chemical compounds used as ingredients, and their contribution to cancer development. We further review recent studies, which display evidence of the microbial-diet interaction in the context of cancer. The field continues to advance our understanding of the development of select cancers and how dietary factors are related to the development, prevention, and treatment of these cancers. Finally, we highlight the science available in the discussion of common misconceptions with regards to cancer and diet. We conclude this review with thoughts on where we believe future research should focus in order to provide the greatest impact towards human health and preventative medicine.

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