A program for establishing the relationship between the structure of chemical compounds and their properties (logical-structural scheme of pattern recognition)

1983 ◽  
Vol 24 (1) ◽  
pp. 159-160
Author(s):  
I. V. Peredunova ◽  
Yu. A. Kruglyak
2010 ◽  
Vol 46 (4) ◽  
pp. 607-616 ◽  
Author(s):  
Daiane Hansen ◽  
Mitsue Haraguchi ◽  
Antonio Alonso

The plant of the genus Pterodon (Fabaceae, Leguminosae), commonly known as 'sucupira' or 'faveira', are disseminated throughout the central region of Brazil and has frequently been used in popular medicine for its anti-rheumatic, analgesic, and anti-inflammatory properties. In recent years, interest in these plants has increased considerably. The biological effects of different phytoextracts and pure metabolites have been investigated in several experimental models in vivo and in vitro. The literature describes flavonoids, triterpene and steroids, while one paper presented studies with proteins isolated from the genus. This review provides an overview of phytochemical and pharmacological research in Pterodon, showing the main chemical compounds studied to date, and focusing on the relationship between these molecules and their biological activity. Furthermore, this study paves the way for more in-depth investigation, isolation and characterization of the molecules of this plant genus.


2021 ◽  
Vol 10 (17) ◽  
pp. 3993
Author(s):  
Andrew Pivovar ◽  
Patrick Oellers

Purpose: To review novel findings in research with ultra-widefield imaging for analysis of peripheral manifestations in macular degeneration (AMD). We introduce the evolving widefield imaging modalities while summarizing the analytical techniques used in data collection of peripheral retinal findings thus far. Our review provides a summary of advancements to date and a commentary on future direction for AMD research. Methods: This is a literature review of all significant publications focused on the relationship between AMD and the retinal periphery conducted within the last two decades. Results and Conclusion: Promising research has been undertaken to elucidate peripheral retinal manifestations in macular degeneration using novel methodology. Advancements in ultra-widefield imaging and fundus autofluorescence have allowed us to elucidate peripheral retinal pigmentary changes, drusen deposition, and much more. Novel grid overlay techniques have been introduced to aid in analyzing these changes for pattern recognition and grouping of findings. This review discusses these findings in detail, providing evidence for the pan-retinal manifestations of AMD. Inter-study discordance in analytical approach highlights a need for more systematic future study.


Author(s):  
Roman Pahomov ◽  
Oleksandr Zyma ◽  
Evgen Dyachenko

The work is devoted to the analysis of injury cases from the electric current influence on the oil and gas complex objects. Theprinciples, the main provisions of the system analysis and the classification of electric traumatism cases at power enterprisesare presented. Main causes and patterns of the electric trauma occurrence on dependence of the various production features,as well as for various categories of workers are determined in the article. The structural scheme of the relationship betweenthe elements of the system "man – electrical engineering – production environment" is given. A set of preventive measuresand practical recommendations that can be successfully applied to assess occupational risk and reduce the level of injuryfrom electric current in the energy sector of Ukraine is proposed.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Guangwei Zhu ◽  
Guijun Zhang ◽  
Meng Wang ◽  
Jingjuan Wang ◽  
Weixin Zeng ◽  
...  

A simple and sensitive HPLC-DAD detection method was established for the simultaneous determination of nine compounds including oxypaeoniflorin, albiflorin, paeoniflorin, benzoylpaeoniflorin, glycyrrhizic acid, liquiritin, isoliquiritin, liquiritigenin, and isoliquiritigenin in the Traditional Chinese Medicinal Prescription Shaoyao-Gancao-Tang (SGT) and we analyze the relationship between therapeutical effect and compatibility of medicines by using an Agilent extend-C18 column at a flow rate of 1 mL/min. The column temperature was maintained at 30°C and the detection wavelength was set at 230 nm for oxypaeoniflorin, albiflorin, paeoniflorin, benzoylpaeoniflorin, and glycyrrhizic acid; 276 nm for liquiritin and liquiritigenin; 360 nm for isoliquiritin and isoliquiritigenin. The total contents of the nine compounds in SGT varied from 4.65 to 20.06 mg/mL. The results of this study showed that the content of chemical compounds of Traditional Chinese Medicinal Prescription is mainly influenced by the dosage and compatibility of medicines and the therapeutical effect of Traditional Chinese Medicinal prescription is mainly influenced by the dosage and compatibility of medicines. The method could be suitable for quality control of SGT with bioactive multicompounds.


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