Structure−Activity Relationships in Lipopolysaccharide Neutralizers:  Design, Synthesis, and Biological Evaluation of a 540-Membered Amphipathic Bisamide Library

Mark R. Burns; Scott A. Jenkins; Stewart J. Wood; Kelly Miller; Sunil A. David

doi:10.1021/cc0500755

Structure−Activity Relationships in Lipopolysaccharide Neutralizers: Design, Synthesis, and Biological Evaluation of a 540-Membered Amphipathic Bisamide Library

Journal of Combinatorial Chemistry ◽

10.1021/cc0500755 ◽

2006 ◽

Vol 8 (1) ◽

pp. 32-43 ◽

Cited By ~ 17

Author(s):

Mark R. Burns ◽

Scott A. Jenkins ◽

Stewart J. Wood ◽

Kelly Miller ◽

Sunil A. David

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Structure Activity Relationships ◽

Structure Activity ◽

Synthesis And Biological Evaluation

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Design, Synthesis, and Biological Evaluation of 1-[(Biarylmethyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as Potent Antifungal Agents: New Insights into Structure-Activity Relationships

ChemMedChem ◽

10.1002/cmdc.201100262 ◽

2011 ◽

Vol 6 (10) ◽

pp. 1806-1815 ◽

Cited By ~ 10

Author(s):

Rémi Guillon ◽

Fabrice Pagniez ◽

Charlotte Rambaud ◽

Carine Picot ◽

Muriel Duflos ◽

...

Keyword(s):

Antifungal Agents ◽

Biological Evaluation ◽

Design Synthesis ◽

Structure Activity Relationships ◽

Structure Activity ◽

Synthesis And Biological Evaluation

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Journal of Medicinal Chemistry ◽

10.1021/jm9800696 ◽

1998 ◽

Vol 41 (15) ◽

pp. 2819-2834 ◽

Cited By ~ 49

Author(s):

Peter S. Dragovich ◽

Stephen E. Webber ◽

Robert E. Babine ◽

Shella A. Fuhrman ◽

Amy K. Patick ◽

...

Keyword(s):

Protease Inhibitors ◽

Biological Evaluation ◽

Human Rhinovirus ◽

Peptide Structure ◽

Design Synthesis ◽

3C Protease ◽

Structure Activity ◽

Synthesis And Biological Evaluation

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 18.1N-Substituted 14-Phenylpropyloxymorphinan-6-ones with Unanticipated Agonist Properties: Extending the Scope of Common Structure−Activity Relationships

Journal of Medicinal Chemistry ◽

10.1021/jm021118o ◽

2003 ◽

Vol 46 (9) ◽

pp. 1758-1763 ◽

Cited By ~ 23

Author(s):

Elisabeth Greiner ◽

Mariana Spetea ◽

Roland Krassnig ◽

Falko Schüllner ◽

Mario Aceto ◽

...

Keyword(s):

Biological Evaluation ◽

Structure Activity Relationships ◽

Common Structure ◽

Structure Activity ◽

Synthesis And Biological Evaluation

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Taxol structure-activity relationships: synthesis and biological evaluation of 10-deoxytaxol

The Journal of Organic Chemistry ◽

10.1021/jo00063a001 ◽

1993 ◽

Vol 58 (11) ◽

pp. 2927-2928 ◽

Cited By ~ 32

Author(s):

Shu Hui Chen ◽

Craig Fairchild ◽

Stephen W. Mamber ◽

Vittorio Farina

Keyword(s):

Biological Evaluation ◽

Structure Activity Relationships ◽

Structure Activity ◽

Synthesis And Biological Evaluation

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New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: Design, synthesis, structure–activity relationships and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.08.011 ◽

2013 ◽

Vol 68 ◽

pp. 433-443 ◽

Cited By ~ 20

Author(s):

Sébastien Fortin ◽

Kevin Brasseur ◽

Nathalie Morin ◽

Éric Asselin ◽

Gervais Bérubé

Keyword(s):

Prostate Cancer ◽

Biological Evaluation ◽

Design Synthesis ◽

Structure Activity Relationships ◽

Structure Activity

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ChemInform Abstract: Structure-Activity Relationships Among DNA Gyrase Inhibitors. Synthesis and Biological Evaluation of 1,2-Dihydro-4,4-dimethyl-1-oxo-2-naphthalenecarboxylic Acids as 1-Carba Bioisosteres of Oxolinic Acid.

Chemischer Informationsdienst ◽

10.1002/chin.198432158 ◽

1984 ◽

Vol 15 (32) ◽

Author(s):

T. HOEGBERG ◽

I. KHANNA ◽

S. D. DRAKE ◽

L. A. MITSCHER ◽

L. L. SHEN

Keyword(s):

Dna Gyrase ◽

Biological Evaluation ◽

Oxolinic Acid ◽

Structure Activity Relationships ◽

Structure Activity ◽

Abstract Structure ◽

Synthesis And Biological Evaluation ◽

Gyrase Inhibitors

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Synthesis and biological evaluation of substituted 2-benzoylpyridine thiosemicarbazones: Novel structure–activity relationships underpinning their anti-proliferative and chelation efficacy

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2012.12.044 ◽

2013 ◽

Vol 23 (4) ◽

pp. 967-974 ◽

Cited By ~ 28

Author(s):

Adeline Y. Lukmantara ◽

Danuta S. Kalinowski ◽

Naresh Kumar ◽

Des R. Richardson

Keyword(s):

Biological Evaluation ◽

Structure Activity Relationships ◽

Structure Activity ◽

Novel Structure ◽

Synthesis And Biological Evaluation

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Structure–activity relationships in platelet-activating factor. Part 13: Synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 or pure antiretroviral activity

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.07.031 ◽

2006 ◽

Vol 14 (23) ◽

pp. 8109-8125 ◽

Cited By ~ 13

Author(s):

Nawal Serradji ◽

Okkacha Bensaid ◽

Marc Martin ◽

Wafa Sallem ◽

Nathalie Dereuddre-Bosquet ◽

...

Keyword(s):

Platelet Activating Factor ◽

Biological Evaluation ◽

Structure Activity Relationships ◽

Piperazine Derivatives ◽

Structure Activity ◽

Synthesis And Biological Evaluation ◽

Anti Hiv ◽

Hiv 1 ◽

Antiretroviral Activity

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Design, Synthesis, Biological Evaluation, and Structure–Activity Relationships of Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl)benzenesulfonates as New Tubulin Inhibitors Mimicking Combretastatin A-4

Journal of Medicinal Chemistry ◽

10.1021/jm200488a ◽

2011 ◽

Vol 54 (13) ◽

pp. 4559-4580 ◽

Cited By ~ 34

Author(s):

Sébastien Fortin ◽

Lianhu Wei ◽

Emmanuel Moreau ◽

Jacques Lacroix ◽

Marie-France Côté ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Tubulin Inhibitors ◽

Structure Activity Relationships ◽

Structure Activity

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ChemInform Abstract: Structure-Activity Relationships Study at the 3′-N Position of Paclitaxel. Part 1. Synthesis and Biological Evaluation of the 3′-(t)-Butylaminocarbonyloxy Bearing Paclitaxel Analogues.

ChemInform ◽

10.1002/chin.199812164 ◽

2010 ◽

Vol 29 (12) ◽

pp. no-no

Author(s):

S.-H. CHEN ◽

M. XUE ◽

S. HUANG ◽

B. H. LONG ◽

C. A. FAIRCHILD ◽

...

Keyword(s):

Biological Evaluation ◽

Structure Activity Relationships ◽

Structure Activity ◽

Abstract Structure ◽

Synthesis And Biological Evaluation

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