scholarly journals Antibacterial Effects of Poly(2-(dimethylamino ethyl)methacrylate) against Selected Gram-Positive and Gram-Negative Bacteria

2010 ◽  
Vol 11 (2) ◽  
pp. 443-453 ◽  
Author(s):  
Lee-Anne B. Rawlinson ◽  
Sinéad M. Ryan ◽  
Giuseppe Mantovani ◽  
Jay A. Syrett ◽  
David M. Haddleton ◽  
...  
Keyword(s):  
Gram Negative Bacteria ◽  
Antibacterial Effects ◽  
Gram Positive ◽  
Gram Negative ◽  
Ethyl Methacrylate

Discriminatory antibacterial effects of calix[n]arene capped silver nanoparticles with regard to Gram positive and Gram negative bacteria

2013 ◽  
Vol 49 (64) ◽  
pp. 7150 ◽  
Author(s):  
Samira Boudebbouze ◽  
Anthony W. Coleman ◽  
Yannick Tauran ◽  
Hela Mkaouar ◽  
Florent Perret ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Gram Negative Bacteria ◽  
Antibacterial Effects ◽  
Gram Positive ◽  
Gram Negative

scholarly journals The Combined Use of Gentamicin and Silver Nitrate in Bone Cement for a Synergistic and Extended Antibiotic Action against Gram-Positive and Gram-Negative Bacteria

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3413
Author(s):  
John Jackson ◽  
Joey Lo ◽  
Eric Hsu ◽  
Helen M. Burt ◽  
Ali Shademani ◽  
...  
Keyword(s):  
Silver Nitrate ◽  
Bone Cement ◽  
Bacterial Resistance ◽  
Synergistic Effects ◽  
Gram Negative Bacteria ◽  
Antibacterial Effects ◽  
Release Rates ◽  
Gram Positive ◽  
Gram Negative ◽  
Combined Use

Using bone cement as a carrier, gentamicin was for years the default drug to locally treat orthopedic infections but has lost favor due to increasing bacterial resistance to this drug. The objective of this study was to investigate the effect of combining gentamicin with silver nitrate in bone cement against S. aureus and P. aeruginosa. Antibacterial effects (CFU counts) of gentamicin and silver were initially studied followed by studies using subtherapeutic concentrations of each in combination. The release rates from cement were measured over 10 days and day 7 release samples were saved and analyzed for antibiotic activity. A strong synergistic effect of combining silver with gentamicin was found using both dissolved drugs and using day 7 bone cement release media for both Gram-positive and Gram-negative bacteria. The cement studies were extended to vancomycin and tobramycin, which are also used in bone cement, and similar synergistic effects were found for day 7 release media with P. aeruginosa but not S. aureus. These studies conclude that the combined use of low loadings of gentamicin and silver nitrate in bone cement may offer an economical and much improved synergistic method of providing anti-infective orthopedic treatments in the clinic.

scholarly journals Antibacterial Effects of Vitamin E: in Vitro Study

2013 ◽  
Vol 7 (2) ◽  
pp. 17-23
Author(s):  
Dalia Abd Al Kader Al-Salih ◽  
Fitua M. Aziz ◽  
Bahir Abdul Razzaq Mshimesh ◽  
Muhanad T. Jehad
Keyword(s):  
Vitamin E ◽  
Pathogenic Bacteria ◽  
In Vitro Study ◽  
The Body ◽  
Diffusion Method ◽  
Gram Negative Bacteria ◽  
Antibacterial Effects ◽  
Gram Positive ◽  
Gram Negative

Overuse of antibiotics has become the major factor for the emergence and dissemination of multi-drug resistant strains of several groups of microorganisms and this lead to search for agents that may have antibacterial effects. Vitamin E emerged as an essential, fat-soluble nutrient in the human body and it is essential, because the body cannot manufacture its own vitamin E, so foods and supplements must provide it. The aim of the present study was to evaluate the effect of vitamin E against pathogenic bacteria. Gram positive and gram negative bacteria were selected as the test microorganisms based on their importance in infections. In this study vitamin E used in four concentrations (50,100,200,400) IU/ml. The agar diffusion method was used to determine antibacterial activity. Results showed that gram negative bacteria were shown to be more resistant than gram positive bacteria. The resistance of gram negative bacteria towards antibacterial substances may be related to lipopolysaccharides in their outer membrane.

scholarly journals In Vitro Antibacterial Activities of Essential Oils and Extracts of Six Herbals Against Gram-positive and Gram-negative Bacteria

2021 ◽  
Author(s):  
Mansour Amin ◽  
Sousan Akrami ◽  
Farkhondeh Haghparasty ◽  
Atiyeh Hakimi
Keyword(s):  
Essential Oils ◽  
Antimicrobial Properties ◽  
Antibacterial Activities ◽  
Test Method ◽  
Gram Negative Bacteria ◽  
Antibacterial Effects ◽  
Gram Positive ◽  
Minimum Concentration ◽  
Gram Negative

Abstract Background: Today, due to the increasing use of chemical drugs and the spread of microbial resistance to synthetic antibiotics, as well as side effects of drugs, the identification and introduction of plant species with medicinal and antimicrobial properties is very important. In this study, the antimicrobial properties of essential oils and extracts of 6 medicinal plants from Ahvaz region, Iran against 12 Gram-positive and Gram-Negative Bacteria were evaluated. Methods: The EOs and extracts were extracted using water distillation with Clevenger apparatus. The antimicrobial properties and determination of the minimum concentration of growth inhibition of herbals were investigated by the modified E-test method. Results: All analyzed extracts and EOs showed antibacterial effects. The antimicrobial activity of Oliveria decumbens was strongest herbals with the least MIC ranges (0.008-0.1 mg/ml for EO, 0.9-20 mg/ml for extract), while the antibacterial effects of Artemisia vulgaris extract and Glycyrrhiza glabra EO with the highest MIC were weaker than the others. According to the effectiveness of plant extracts on bacteria, Pseudomonas aeruginosa was resistant to all extracts except Oliveria decumbens. In contrast, Bacillus cereus was more sensitive than other strains against analyzed EOs and extracts.Conclusions: It seems that due to the antimicrobial properties of the extracts and essential oils observed in this study, they can be used as an alternative to antimicrobial drugs after more extensive studies.

scholarly journals Antibacterial effects of commercially available phosphates on selected microorganisms

2008 ◽  
Vol 56 (5) ◽  
pp. 19-24 ◽  
Author(s):  
Leona Buňková ◽  
Pavel Pleva ◽  
František Buňka ◽  
Pavel Valášek ◽  
Stanislav Kráčmar
Keyword(s):  
Inhibitory Effect ◽  
Gram Negative Bacteria ◽  
Bacterial Strains ◽  
Inhibitory Effects ◽  
Antibacterial Effects ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
The Individual ◽  
Phosphate Salts

In the food industry, phosphates, polyphosphates and their salts are used, for example, as emul­si­fying agents in the production of processed cheese. The inhibitory effects of three commercially avai­la­ble phosphates and polyphosphates differing in their chain length (690, S9 and HBS) were tested on a set of 15 gram-positive or gram-negative CCM (Czech Collection of Microorganisms) strains and on 12 bacterial strains isolated from processed cheeses. Five different concentrations of each phosphate were chosen (0.1, 0.2, 0.3, 0.4 and 0.5% w/v) in order to observe the inhibitory effects of the phosphate salts on the growth of the microorganisms tested. Sensitivity of the individual bacterial strains to phosphates was observed of a liquid cultivation medium which was supplemented with applied salts. Subsequently, the growth in cells was determined by measuring optical density at a wavelength of 600 nm. According to the results, 690 and S9 phosphates, containing mainly orthophosphates, diphosphates (pyrophosphates) and short-chain polyphosphates, do not have a significant inhibitory effect on the growth of the tested bacteria. Significant inhibitory effects were observed only in HBS salt (a mixture of long-chain polyphosphates), which showed antibacterial effects on all gram-positive bacteria tested (both the CCM strains and those isolated from processed cheeses). The antibacterial effect of phosphates on gram-positive microorganisms is growing with the increasing length of the polyphosphate chain. This study has not proved a significant effect of the phosphates tested on the growth of gram-negative bacteria used.

Rapid demonstration of septic or infectious arthritis due to Gram-negative bacteria

1992 ◽  
Vol 50 (1) ◽  
pp. 686-687
Author(s):  
Jacob S. Hanker ◽  
Paul R. Gross ◽  
Beverly L. Giammara
Keyword(s):  
Chronic Arthritis ◽  
Blood Cultures ◽  
Gram Negative Bacteria ◽  
Infectious Arthritis ◽  
Bacterial Arthritis ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria

Blood cultures are positive in approximately only 50 per cent of the patients with nongonococcal bacterial infectious arthritis and about 20 per cent of those with gonococcal arthritis. But the concept that gram-negative bacteria could be involved even in chronic arthritis is well-supported. Gram stains are more definitive in staphylococcal arthritis caused by gram-positive bacteria than in bacterial arthritis due to gram-negative bacteria. In the latter situation where gram-negative bacilli are the problem, Gram stains are helpful for 50% of the patients; they are only helpful for 25% of the patients, however, where gram-negative gonococci are the problem. In arthritis due to gram-positive Staphylococci. Gramstained smears are positive for 75% of the patients.

In-vitro Antioxidant and Antibacterial Activity of Methanolic Extract of Shorea robusta Gaertn. F. Resin

2016 ◽  
Vol 6 (4) ◽  
pp. 68
Author(s):  
Sushma Vashisht ◽  
Manish Pal Singh ◽  
Viney Chawla
Keyword(s):  
Antibacterial Activity ◽  
Methanolic Extract ◽  
Diffusion Method ◽  
Gram Negative Bacteria ◽  
Disc Diffusion ◽  
Gram Positive ◽  
Gram Negative ◽  
Shorea Robusta ◽  
Dose Dependent ◽  
Resin Extract

The methanolic extract of the resin of Shorea robusta was subjected to investigate its antioxidant and antibacterial properties its utility in free radical mediated diseases including diabetic, cardiovascular, cancer etc. The methanol extract of the resin was tested for antioxidant activity using scavenging activity of DPPH (1,1-diphenyl-2-picrylhydrazil) radical method, reducing power by FeCl3 and antibacterial activity against gram positive and gram negative bacteria using disc diffusion method. The phytochemical screening considered the presence of triterpenoids, tannins and flavoniods. Overall, the plant extract is a source of natural antioxidants which might be helpful in preventing the progress of various oxidative stress mediated diseases including aging. The half inhibition concentration (IC50) of resin extract of Shorea robusta and ascorbic acid were 35.60 µg/ml and 31.91 µg/ml respectively. The resin extract exhibit a significant dose dependent inhibition of DPPH activity. Antibacterial activity was observed against gram positive and gram negative bacteria in dose dependent manner.Key Words: Shorea robusta, antioxidant, antibacterial, Disc-diffusion, DPPH.

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