Stimuli Responsive Self-Assembled Hydrogel of a Low Molecular Weight Free Dipeptide with Potential for Tunable Drug Delivery

2008 ◽  
Vol 9 (8) ◽  
pp. 2244-2250 ◽  
Author(s):  
Jiban J. Panda ◽  
Aseem Mishra ◽  
Atanu Basu ◽  
Virander S. Chauhan
Keyword(s):  
Drug Delivery ◽  
Molecular Weight ◽  
Low Molecular Weight ◽  
Stimuli Responsive ◽  
Self Assembled

A Hydrogel-based Implantable Multidrug Antitubercular Formulation Outperforms Oral Delivery.

Nanoscale ◽  
2021 ◽  
Author(s):  
Sanjay Pal ◽  
Vijay Soni ◽  
Sandeep Kumar ◽  
Somesh K Jha ◽  
Nihal Medatwal ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Molecular Weight ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Delivery ◽  
Low Molecular Weight ◽  
Front Line ◽  
Antitubercular Drugs

We present a non-immunogenic, injectable, low molecular weight, amphiphilic hydrogel-based drug delivery system (TB-Gel) that can entrap a cocktail of four front-line antitubercular drugs isoniazid, rifampicin, pyrazinamide, and ethambutol. We...

scholarly journals Thermally tunable selective formation of self-assembled fibers into two orthogonal directions in oriented liquid-crystalline smectic templates

2020 ◽  
Vol 56 (69) ◽  
pp. 9954-9957
Author(s):  
Daisuke Yamaguchi ◽  
Yuka Ikemoto ◽  
Takashi Kato
Keyword(s):  
Molecular Weight ◽  
Self Assembly ◽  
Liquid Crystalline ◽  
Layered Structures ◽  
Low Molecular Weight ◽  
Smectic A ◽  
Orthogonal Grid ◽  
Self Assembled ◽  
Low Molecular Weight Gelators ◽  
Selective Formation

Two orthogonal (grid-like) and one directional fibrous structures are selectively formed through anisotropic self-assembly of low-molecular-weight gelators in liquid-crystalline smectic A templates depending on thermally tuned layered structures.

Liposome coated with low molecular weight chitosan and its potential use in ocular drug delivery

2009 ◽  
Vol 379 (1) ◽  
pp. 131-138 ◽  
Author(s):  
Ning Li ◽  
Chunyang Zhuang ◽  
Mi Wang ◽  
Xiyang Sun ◽  
Shufang Nie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Molecular Weight ◽  
Ocular Drug Delivery ◽  
Low Molecular Weight ◽  
Low Molecular Weight Chitosan ◽  
Potential Use

scholarly journals Progress in Microneedle-Mediated Protein Delivery

2020 ◽  
Vol 9 (2) ◽  
pp. 542 ◽  
Author(s):  
Rezvan Jamaledin ◽  
Concetta Di Natale ◽  
Valentina Onesto ◽  
Zahra Taraghdari ◽  
Ehsan Zare ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Molecular Weight ◽  
Stratum Corneum ◽  
Transdermal Drug Delivery ◽  
Protein Delivery ◽  
Scaling Up ◽  
Low Molecular Weight ◽  
Non Invasive ◽  
Promising Tool ◽  
Transdermal Patches

The growing demand for patient-compliance therapies in recent years has led to the development of transdermal drug delivery, which possesses several advantages compared with conventional methods. Delivering protein through the skin by transdermal patches is extremely difficult due to the presence of the stratum corneum which restricts the application to lipophilic drugs with relatively low molecular weight. To overcome these limitations, microneedle (MN) patches, consisting of micro/miniature-sized needles, are a promising tool to perforate the stratum corneum and to release drugs and proteins into the dermis following a non-invasive route. This review investigates the fabrication methods, protein delivery, and translational considerations for the industrial scaling-up of polymeric MNs for dermal protein delivery.

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