Solution Structure of the Conserved Segment of the Myb Cognate DNA Sequence by 2D NMR, Spectral Simulation, Restrained Energy Minimization, and Distance Geometry Calculations

Biochemistry ◽  
1995 ◽  
Vol 34 (17) ◽  
pp. 5913-5922 ◽  
Author(s):  
P. K. Radha ◽  
Anup Madan ◽  
R. Nibedita ◽  
R. V. Hosur
Keyword(s):  
Dna Sequence ◽  
Energy Minimization ◽  
Solution Structure ◽  
Distance Geometry ◽  
2D Nmr ◽  
Spectral Simulation

Solution structure of GCCAAT recognition motif by 2D NMR, spectral simulation, molecular modeling, and distance geometry calculations

Biochemistry ◽  
1993 ◽  
Vol 32 (35) ◽  
pp. 9053-9064 ◽  
Author(s):  
R. Nibedita ◽  
R. Ajay Kumar ◽  
A. Majumdar ◽  
R. V. Hosur ◽  
Girjesh Govil ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Solution Structure ◽  
Distance Geometry ◽  
2D Nmr ◽  
Spectral Simulation ◽  
Recognition Motif

Solution Structure of a GA Mismatch DNA Sequence, d(CCATGAATGG)2, Determined by 2D NMR and Structural Refinement Methods

Biochemistry ◽  
1994 ◽  
Vol 33 (5) ◽  
pp. 1053-1062 ◽  
Author(s):  
Karen L. Greene ◽  
Robert L. Jones ◽  
Ying Li ◽  
Howard Robinson ◽  
Andrew H.-J. Wang ◽  
...  
Keyword(s):  
Dna Sequence ◽  
Solution Structure ◽  
2D Nmr ◽  
Structural Refinement

scholarly journals Combined use of NMR, distance geometry, and restrained energy minimization for the conformational analysis of 8-lysine–vasopressin

1992 ◽  
Vol 70 (7) ◽  
pp. 1950-1955 ◽  
Author(s):  
Chin Yu ◽  
Ta-Horng Yang ◽  
Chao-Jung Yeh ◽  
Li-Chin Chuang
Keyword(s):  
Conformational Analysis ◽  
Energy Minimization ◽  
Distance Geometry ◽  
2D Nmr ◽  
Membered Ring ◽  
Dmso Solution ◽  
Tail Region ◽  
Lysine Vasopressin ◽  
Combined Use ◽  
Neurohypophyseal Hormone

The conformation of the neurohypophyseal hormone, 8-lysine–vasopressin, in DMSO solution has been determined from 2D-NMR and distance geometry followed by the restrained energy minimization calculation. The conformation of 8-lysin–vasopressin in the 20-membered ring region is well defined but the acyclic tripeptide tail region is disordered.

scholarly journals Solution structure of μ-conotoxin GIIIA analysed by 2D-NMR and distance geometry calculations

FEBS Letters ◽  
1991 ◽  
Vol 278 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Karl Heinz Ott ◽  
Stefan Becker ◽  
Robert D. Gordon ◽  
Heinz Rüterjans
Keyword(s):  
Solution Structure ◽  
Distance Geometry ◽  
2D Nmr

scholarly journals Antitumor Trans Platinum Adducts of GMP and AMP

2000 ◽  
Vol 7 (4) ◽  
pp. 169-176 ◽  
Author(s):  
Yangzhong Liu ◽  
Maria F. Sivo ◽  
Giovanni Natile ◽  
Einar Sletten
Keyword(s):  
Antitumor Activity ◽  
Energy Minimization ◽  
Qualitative Agreement ◽  
Early Stage ◽  
2D Nmr ◽  
The Other ◽  
Coordination Geometry ◽  
Nmr Data ◽  
Monofunctional Adducts

Recently it has been shown that several analogues of the clinically ineffective trans-DDP exhibit antitumor activity comparable to that of cis-DDP. The present paper describes the binding of antitumor trans-[PtCl2(E-iminoether)2] (trans-EE) to guanosinemonophosphate (GMP) and adenosinemonophosphate (AMP). We have used HPLC and H1 and N15 NMR to characterize the different adducts. In the case of a 1:1 mixture of trans-EE and GMP, at an early stage of the reaction, a monofunctional adduct is formed which, subsequently, is partly converted into a monosolvated monofunctional species. After about 70 hours an equilibrium is established between chloro and solvato monofunctional adducts at a ratio of 30/70. In the presence of excess GMP (4:1) the initially formed monofunctional adducts react further to give two bifunctional adducts, one with the iminoether ligands in their original E configurations and the other with the iminoether ligands having one E and the other, Z configurations. The coordination geometry obtained by energy minimization calculations is in qualitative agreement with 2D NMR data.

Studies of the solution structure of the bleomycin A2-iron(II)-carbon monoxide complex by means of two-dimensional NMR spectroscopy and distance geometry calculations

1990 ◽  
Vol 112 (21) ◽  
pp. 7462-7474 ◽  
Author(s):  
Marcel A. J. Akkerman ◽  
Eric W. J. F. Neijman ◽  
Sybren S. Wijmenga ◽  
Cornelis W. Hilbers ◽  
Wolfgang Bermel
Keyword(s):  
Carbon Monoxide ◽  
Nmr Spectroscopy ◽  
Solution Structure ◽  
Distance Geometry ◽  
Two Dimensional
Sign in / Sign up

Export Citation Format

Share Document