Refined structure of melittin bound to perdeuterated dodeclylphoscholine micelles as studied by 2D-NMR and distance geometry calculation

1991 ◽  
Vol 9 (2) ◽  
pp. 81-89 ◽  
Author(s):  
Teikichi Ikura ◽  
Nobuhiro Gō ◽  
Fuyuhiko Inagaki
Keyword(s):  
Distance Geometry ◽  
2D Nmr

scholarly journals Combined use of NMR, distance geometry, and restrained energy minimization for the conformational analysis of 8-lysine–vasopressin

1992 ◽  
Vol 70 (7) ◽  
pp. 1950-1955 ◽  
Author(s):  
Chin Yu ◽  
Ta-Horng Yang ◽  
Chao-Jung Yeh ◽  
Li-Chin Chuang
Keyword(s):  
Conformational Analysis ◽  
Energy Minimization ◽  
Distance Geometry ◽  
2D Nmr ◽  
Membered Ring ◽  
Dmso Solution ◽  
Tail Region ◽  
Lysine Vasopressin ◽  
Combined Use ◽  
Neurohypophyseal Hormone

The conformation of the neurohypophyseal hormone, 8-lysine–vasopressin, in DMSO solution has been determined from 2D-NMR and distance geometry followed by the restrained energy minimization calculation. The conformation of 8-lysin–vasopressin in the 20-membered ring region is well defined but the acyclic tripeptide tail region is disordered.

scholarly journals Solution structure of μ-conotoxin GIIIA analysed by 2D-NMR and distance geometry calculations

FEBS Letters ◽  
1991 ◽  
Vol 278 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Karl Heinz Ott ◽  
Stefan Becker ◽  
Robert D. Gordon ◽  
Heinz Rüterjans
Keyword(s):  
Solution Structure ◽  
Distance Geometry ◽  
2D Nmr

Solution structure of GCCAAT recognition motif by 2D NMR, spectral simulation, molecular modeling, and distance geometry calculations

Biochemistry ◽  
1993 ◽  
Vol 32 (35) ◽  
pp. 9053-9064 ◽  
Author(s):  
R. Nibedita ◽  
R. Ajay Kumar ◽  
A. Majumdar ◽  
R. V. Hosur ◽  
Girjesh Govil ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Solution Structure ◽  
Distance Geometry ◽  
2D Nmr ◽  
Spectral Simulation ◽  
Recognition Motif

Proton 2D NMR and distance geometry study of the folding of Ecballium elaterium trypsin inhibitor, a member of the squash inhibitors family

Biochemistry ◽  
1989 ◽  
Vol 28 (6) ◽  
pp. 2392-2398 ◽  
Author(s):  
Annie Heitz ◽  
Laurent Chiche ◽  
Le Nguyen Dung ◽  
Bertrand Castro
Keyword(s):  
Trypsin Inhibitor ◽  
Distance Geometry ◽  
2D Nmr

2D NMR studies on muscle and cerebral metabolism in vivo

1994 ◽  
Vol 91 ◽  
pp. 697-703 ◽  
Author(s):  
B Gillet ◽  
BT Doan ◽  
C Verre-Sebrie ◽  
O Fedeli ◽  
JC Beloeil ◽  
...  
Keyword(s):  
Cerebral Metabolism ◽  
2D Nmr ◽  
Nmr Studies

Demonstration of 2D NMR Spectroscopy in a Powered Magnet at 25 T Using Cascade Field Regulation

2019 ◽  
Author(s):  
Benjamin D. McPheron ◽  
Jeffrey L. Schiano ◽  
Brian F. Thomson ◽  
Kiran K. Shetty ◽  
William W. Brey
Keyword(s):  
Nmr Spectroscopy ◽  
2D Nmr ◽  
2D Nmr Spectroscopy

Lupane Type Triterpene Isolated from the Leaves of Thecacoris Annobonea (Euphorbiaceae)

2013 ◽  
Vol 12 (10) ◽  
pp. 695-701
Author(s):  
Herve Martial Poumale Poumale ◽  
Alphonsine Nkapwa Guedem ◽  
Louis Pergaud Sandjo ◽  
Bonaventure Tchaleu Ngadjui ◽  
Yoshihito Shiono
Keyword(s):  
Antimicrobial Activity ◽  
Root Growth ◽  
Betulinic Acid ◽  
Aristolochic Acid ◽  
2D Nmr ◽  
Aristolochic Acid I

A new lupane type triterpene (1), together with betulinic acid (2), friedelin (3), aristolochic acid I (4), alpinumisoflavone (5) and 4’-O-methylepinumisoflavone (6) have been isolated from the leaves of Thecacoris annobonea. The structure of the new compound was elucidated on the basis of 1 and 2D NMR experiments. The isolated compounds were evaluated for their phytotoxicity and antimicrobial activity. 1 exhibited significant antimicrobial activity at 30 μg/ml and compounds 1, 2, 3, 4, 5 and 6 inhibited root growth lettuce at 100 μg/ml. 

Isolation of New Glycosides from Anemarrhena Asphodeloides Rhizome and Screening of their Anticancer Activity

2019 ◽  
Vol 16 (6) ◽  
pp. 474-477 ◽  
Author(s):  
Pham Van Khang ◽  
Nguyen Thi Hien Lan ◽  
Le Quang Truong ◽  
Mai Thi Minh Chau ◽  
Mai Xuan Truong ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Spectral Data ◽  
Cell Lines ◽  
Cancer Cell ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Ic50 Values ◽  
Nmr Techniques ◽  
Inhibitory Activities ◽  
Anemarrhena Asphodeloides

In this report, two new steroidal glycosides were isolated and determined from n-butanol fraction of A.asphodeloides. The structures were confirmed in comparison with the spectral data of known compounds by using different spectroscopic analysis approaches including 1D & 2D-NMR techniques and HRMS. The anti-proliferation screening against cancer cell lines A549 and HeLa indicated that compound 1 exhibited good inhibitory activities with IC50 values of 0.79 and 0.55 µg/mL, respectively.

Nuclear Magnetic Resonance Spectroscopic Behaviour of Some Selective Natural Flavonoids: A Look Through

2020 ◽  
Vol 17 (2) ◽  
pp. 185-196
Author(s):  
Shyamal K. Jash ◽  
Dilip Gorai ◽  
Lalan C. Mandal ◽  
Rajiv Roy
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Natural Products ◽  
Magnetic Resonance ◽  
Hard Core ◽  
2D Nmr ◽  
Vital Role ◽  
Spectral Technique ◽  
Nmr Techniques ◽  
Significant Class ◽  
Nuclear Magnetic

Flavonoids are considered as a significant class of compounds among the natural products, exhibiting a variety of structural skeletons as well as multidirectional biological potentials. In structural elucidations of natural products, Nuclear Magnetic Resonance (NMR) spectroscopy has been playing a vital role; the technique is one of the sharpest tools in the hands of natural products chemists. The present resume deals with hard-core applications of such spectral technique, particularly in structural elucidation of flavonoids; different NMR techniques including 1H-NMR, 13C-NMR, and 2D-NMR [viz. 1H-1H COSY, COLOC, HMBC, HMQC] are described in detail.

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