Bifunctional Magnetic-Fluorescent Nanoparticles: Synthesis, Characterization, and Cell Imaging

2015 ◽  
Vol 7 (9) ◽  
pp. 5226-5232 ◽  
Author(s):  
Yanjiao Lu ◽  
Yang Zheng ◽  
Shusen You ◽  
Feng Wang ◽  
Zhuo Gao ◽  
...  
2019 ◽  
Vol 10 (17) ◽  
pp. 2162-2169 ◽  
Author(s):  
Zengfang Huang ◽  
Runze Wang ◽  
Yali Chen ◽  
Xiaobo Liu ◽  
Ke Wang ◽  
...  

This work reports the fabrication of a novel polymerizable AIE dye and its amphiphilic PEG-TS fluorescent polymers via RAFT polymerization, which were attractive for the application in cell imaging.


2015 ◽  
Vol 33 (8) ◽  
pp. 888-896 ◽  
Author(s):  
Xiaoming Hu ◽  
Chao Yin ◽  
Wenbo Hu ◽  
Zhen Yang ◽  
Jie Li ◽  
...  

2018 ◽  
Vol 14 (10) ◽  
pp. 1745-1753 ◽  
Author(s):  
Wenkun Han ◽  
Song Zhang ◽  
Jingyu Qian ◽  
Jianxu Zhang ◽  
Xuanhang Wang ◽  
...  

2021 ◽  
pp. 000370282110275
Author(s):  
Rachel Rex ◽  
Soumik Siddhanta ◽  
Ishan Barman

Fluorescence imaging is a major driver of discovery in biology, and an invaluable asset in clinical diagnostics. To overcome quenching limitations of conventional fluorescent dyes and further improve intensity, nanoparticle-based constructs have been the subject of intense investigation, and within this realm, dye-doped silica-coated nanoparticles have garnered significant attention. Despite their growing popularity in research, fluorescent silica nanoparticles suffer from a significant flaw. The degradation of these nanoparticles in biological media by hydrolytic dissolution is underreported, leading to serious misinterpretations, and limiting their applicability for live cell and in vivo imaging. Here, the development of an ultra-stable, dye-embedded, silica-coated metal nanoparticle is reported, and its superior performance in long-term live cell imaging is demonstrated. While conventional dye-doped silica nanoparticles begin to degrade within an hour in aqueous media, by leveraging a modified liquid calcination process, this new construct is shown to be stable for at least 24 h. The stability of this metal-enhanced fluorescent probe in biologically relevant temperatures and media, and its demonstrated utility for cell imaging, paves the way for its future adoption in biomedical research.


RSC Advances ◽  
2017 ◽  
Vol 7 (48) ◽  
pp. 30229-30241 ◽  
Author(s):  
Kai Li ◽  
Yang Zhang ◽  
Bing Qiao ◽  
Furong Tao ◽  
Tianduo Li ◽  
...  

Compounds 1–4 were synthesized, and the optical properties and mechanisms were investigated. Compound 4 was applied to the cell imaging.


RSC Advances ◽  
2019 ◽  
Vol 9 (56) ◽  
pp. 32601-32607 ◽  
Author(s):  
Yali Chen ◽  
Zengfang Huang ◽  
Xiaobo Liu ◽  
Liucheng Mao ◽  
Jinying Yuan ◽  
...  

This work reported the fabrication of a novel AIE-active dye and its amphiphilic PEG-TPD fluorescent polymers via one-pot combination of RAFT polymerization and Hantzsch reaction, which showed potential applications in bioimaging.


RSC Advances ◽  
2017 ◽  
Vol 7 (65) ◽  
pp. 40842-40848 ◽  
Author(s):  
Xiaoyu Wang ◽  
Lu Liu ◽  
Shuxian Zhu ◽  
Jinghong Peng ◽  
Lidong Li

Novel organic fluorescent nanoparticles based on exciplex were prepared and have been successfully applied in live cell imaging.


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