scholarly journals Facile fabrication of AIE/AIEE-active fluorescent nanoparticles based on barbituric for cell imaging applications

RSC Advances ◽  
2017 ◽  
Vol 7 (48) ◽  
pp. 30229-30241 ◽  
Author(s):  
Kai Li ◽  
Yang Zhang ◽  
Bing Qiao ◽  
Furong Tao ◽  
Tianduo Li ◽  
...  

Compounds 1–4 were synthesized, and the optical properties and mechanisms were investigated. Compound 4 was applied to the cell imaging.

2020 ◽  
Vol 17 ◽  
Author(s):  
Dilawar Hassan ◽  
Hadi Bakhsh ◽  
Asif M. Khurram ◽  
Shakeel A. Bhutto ◽  
Nida S. Jalbani ◽  
...  

Background: The optical properties of nanomaterials have evolved enormously with the introduction of nanotechnology. The property of materials to absorb and/or emit specific wavelength has turned them into one of the most favourite candidates to be effectively utilized in different sensing applications e.g organic light emission diodes (OLEDs) sensors, gas sensors, biosensors and fluorescent sensors. These materials have been reported as a sensor in the field of tissue and cell imaging, cancer detection and detection of environmental contaminants etc. Fluorescent nanomaterials are heling in rapid and timely detection of various contaminants that greatly impact the quality of life and food, that is exposed to these contaminants. Later, all the contaminants have been investigated to be most perilous entities that momentously affect the life span of the animals and humans who use those foods which have been contaminated. Objective: In this review, we will discuss about various methods and approaches to synthesize the fluorescent nanoparticles and quantum dots (QDs) and their applications in various fields. The application will include the detection of various environmental contaminants and bio-medical applications. We will discuss the possible mode of action of the nanoparticles when used as sensor for the environmental contaminants as well as the surface modification of some fluorescent nanomaterials with anti-body and enzyme for specific detection in animal kingdom. We will also describe some RAMAN based sensors as well as some optical sensing-based nanosensors. Conclusion: Nanotechnology has enabled to play with the size, shape and morphology of materials in the nanoscale. The physical, chemical and optical properties of materials change dramatically when they are reduced to nanoscale. The optical properties can become choosy in terms of emission or absorption of wavelength in the size range and can result in production of very sensitive optical sensor. The results show that the use of fluorescent nanomaterials for the sensing purposes are helping a great deal in the sensing field.


2014 ◽  
Vol 30 (6) ◽  
pp. 987-990
Author(s):  
Meng Liu ◽  
Xiaofei Qi ◽  
Xionggang Wu ◽  
Hengning Zhang

2018 ◽  
Vol 14 (10) ◽  
pp. 1745-1753 ◽  
Author(s):  
Wenkun Han ◽  
Song Zhang ◽  
Jingyu Qian ◽  
Jianxu Zhang ◽  
Xuanhang Wang ◽  
...  

2021 ◽  
pp. 000370282110275
Author(s):  
Rachel Rex ◽  
Soumik Siddhanta ◽  
Ishan Barman

Fluorescence imaging is a major driver of discovery in biology, and an invaluable asset in clinical diagnostics. To overcome quenching limitations of conventional fluorescent dyes and further improve intensity, nanoparticle-based constructs have been the subject of intense investigation, and within this realm, dye-doped silica-coated nanoparticles have garnered significant attention. Despite their growing popularity in research, fluorescent silica nanoparticles suffer from a significant flaw. The degradation of these nanoparticles in biological media by hydrolytic dissolution is underreported, leading to serious misinterpretations, and limiting their applicability for live cell and in vivo imaging. Here, the development of an ultra-stable, dye-embedded, silica-coated metal nanoparticle is reported, and its superior performance in long-term live cell imaging is demonstrated. While conventional dye-doped silica nanoparticles begin to degrade within an hour in aqueous media, by leveraging a modified liquid calcination process, this new construct is shown to be stable for at least 24 h. The stability of this metal-enhanced fluorescent probe in biologically relevant temperatures and media, and its demonstrated utility for cell imaging, paves the way for its future adoption in biomedical research.


2019 ◽  
Vol 10 (17) ◽  
pp. 2162-2169 ◽  
Author(s):  
Zengfang Huang ◽  
Runze Wang ◽  
Yali Chen ◽  
Xiaobo Liu ◽  
Ke Wang ◽  
...  

This work reports the fabrication of a novel polymerizable AIE dye and its amphiphilic PEG-TS fluorescent polymers via RAFT polymerization, which were attractive for the application in cell imaging.


2016 ◽  
Vol 4 (2) ◽  
pp. 198-201 ◽  
Author(s):  
Haiyin Li ◽  
Jiafu Chang ◽  
Ting Hou ◽  
Feng Li

An AIE-active amphiphile containing a tetraphenylethene moiety and a quarternary ammonium salt group, with an ultra low CMC, desirable optical properties, good water dispersibility and excellent biocompatibility, was prepared and investigated, and the as-prepared amphiphile was successfully applied in cell imaging.


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