scholarly journals Controlled Release of Carbon Monoxide from a Pseudo Electron-Deficient Organometallic Complex

ACS Omega ◽  
2018 ◽  
Vol 3 (11) ◽  
pp. 15623-15627 ◽  
Author(s):  
Anaïs Pitto-Barry ◽  
Nicolas P. E. Barry
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release ◽  
Organometallic Complex

scholarly journals A Novel H2O2 Generator for Tumor Chemotherapy-Enhanced CO Gas Therapy

2021 ◽  
Vol 11 ◽  
Author(s):  
Yang Li ◽  
Zeming Liu ◽  
Weng Zeng ◽  
Ziqi Wang ◽  
Chunping Liu ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release ◽  
Tumor Microenvironment ◽  
Tumor Site ◽  
Co Poisoning ◽  
Chemotherapy Agent ◽  
Manganese Carbonyl ◽  
Co Gas

Carbon monoxide (CO) gas therapy is a promising cancer treatment. However, gas delivery to the tumor site remains problematic. Proper tunable control of CO release in tumors is crucial to increasing the efficiency of CO treatment and reducing the risk of CO poisoning. To overcome such challenges, we designed ZCM, a novel stable nanotechnology delivery system comprising manganese carbonyl (MnCO) combined with anticancer drug camptothecin (CPT) loaded onto a zeolitic imidazole framework-8 (ZIF-8). After intravenous injection, ZCM gradually accumulates in cancerous tissues, decomposing in the acidic tumor microenvironment, releasing CPT and MnCO. CPT acts as a chemotherapy agent destroying tumors and producing copious H2O2. MnCO can react with the H2O2 to generate CO, powerfully damaging the tumor. Both in vitro and in vivo experiments indicate that the ZCM system is both safe and has excellent tumor inhibition properties. ZCM is a novel system for CO controlled release, with significant potential to improve future cancer therapy.

New photo-CORMs: Deeply-coloured biocompatible rhenium complexes for the controlled release of carbon monoxide

2015 ◽  
Vol 435 ◽  
pp. 174-177 ◽  
Author(s):  
Elham Kianfar ◽  
Christine Schäfer ◽  
Mohammad Reza Lornejad-Schäfer ◽  
Engelbert Portenkirchner ◽  
Günther Knör
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release ◽  
Rhenium Complexes

Controlled Release of Reactive Gases: A Tale of Taming Carbon Monoxide

ChemPlusChem ◽  
2020 ◽  
Vol 85 (7) ◽  
pp. 1529-1533
Author(s):  
Anne K. Ravn ◽  
Martin B. Johansen ◽  
Troels Skrydstrup
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release ◽  
Reactive Gases

scholarly journals Carbon monoxide – physiology, detection and controlled release

2014 ◽  
Vol 50 (28) ◽  
pp. 3644-3660 ◽  
Author(s):  
Stefan H. Heinemann ◽  
Toshinori Hoshi ◽  
Matthias Westerhausen ◽  
Alexander Schiller
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release

Effector systems, sensing and controlled release of the biosignaling molecule carbon monoxide are featured.

Carbon Monoxide and Its Controlled Release: Therapeutic Application, Detection, and Development of Carbon Monoxide Releasing Molecules (CORMs)

2017 ◽  
Vol 61 (7) ◽  
pp. 2611-2635 ◽  
Author(s):  
Ken Ling ◽  
Fang Men ◽  
Wei-Ci Wang ◽  
Ya-Qun Zhou ◽  
Hao-Wen Zhang ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release ◽  
Therapeutic Application

ChemInform Abstract: Carbon Monoxide - Physiology, Detection and Controlled Release

ChemInform ◽  
2014 ◽  
Vol 45 (21) ◽  
pp. no-no
Author(s):  
Stefan H. Heinemann ◽  
Toshinori Hoshi ◽  
Matthias Westerhausen ◽  
Alexander Schiller
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release

scholarly journals Controlled Release of Carbon Monoxide Based on Nanomaterials and Their Biomedical Applications

2019 ◽  
Vol 77 (5) ◽  
pp. 406
Author(s):  
Xiaolei Zhang ◽  
Gan Tian ◽  
Xia Zhang ◽  
Qing Wang ◽  
Zhanjun Gu
Keyword(s):  
Carbon Monoxide ◽  
Controlled Release ◽  
Biomedical Applications

Carbon monoxide poisoning

2000 ◽  
Vol 12 (4) ◽  
pp. 354-357
Author(s):  
David R Smart ◽  
Paul D Mark
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning
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