Graphene-Coated Glass Substrate for Continuous Wave Laser Desorption and Atmospheric Pressure Mass Spectrometric Imaging of a Live Hippocampal Tissue

2019 ◽  
Vol 11 (30) ◽  
pp. 27153-27161 ◽  
Author(s):  
Jae Young Kim ◽  
Heejin Lim ◽  
Sun Young Lee ◽  
Cheol Song ◽  
Ji-Won Park ◽  
...  
Keyword(s):  
Glass Substrate ◽  
Atmospheric Pressure ◽  
Continuous Wave ◽  
Laser Desorption ◽  
Mass Spectrometric ◽  
Continuous Wave Laser ◽  
Mass Spectrometric Imaging ◽  
Coated Glass Substrate ◽  
Coated Glass ◽  
Wave Laser

scholarly journals Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

RSC Advances ◽  
2018 ◽  
Vol 8 (15) ◽  
pp. 8021-8025 ◽  
Author(s):  
Jae Young Kim ◽  
Eun Seok Seo ◽  
Hee Jin Lim ◽  
Hyunmin Kim ◽  
Ji-Won Park ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Continuous Wave ◽  
Mass Spectrometric ◽  
Continuous Wave Laser ◽  
Mass Spectrometric Imaging ◽  
Tissue Slices ◽  
Hippocampal Tissue ◽  
Wave Laser ◽  
532 Nm ◽  
Resolution Mass

Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter.

Gold-Nanoparticle Layer Substrate Assisted Transmission-Mode Laser Desorption for Atmospheric Pressure Mass Spectrometry Imaging

2020 ◽  
Vol 12 (10) ◽  
pp. 1517-1523
Author(s):  
Jae Young Kim ◽  
Heejin Lim ◽  
Sun Young Lee ◽  
Gwanjin Lee ◽  
Dong-Kwon Lim ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gold Nanoparticle ◽  
Atmospheric Pressure ◽  
Mass Spectrometry Imaging ◽  
Continuous Wave ◽  
Continuous Wave Laser ◽  
Fresh Tissue ◽  
Mode Laser ◽  
Nanoparticle Layer ◽  
Wave Laser

We demonstrate continuous-wave laser-based ambient mass spectrometry imaging with the use of a gold-nanoparticle layer substrate. When a fresh tissue slice is placed on a gold-nanoparticle layer substrate and irradiated with a 532-nm continuous-wave laser, the transmission-mode laser configuration provides precise desorption performance to facilitate mass spectrometry imaging. The subsequent ionization process with nonthermal atmospheric pressure plasma jets generates sufficient amounts of molecular ions. By using this method, micrometer-spatial-resolution mass spectrometry imaging of humid tissues can be obtained. The gold-nanoparticle layer substrates can be prepared and stored in advance of the experiment, resulting in simplified specimen preparation and an advantage in faster preparing of fresh tissue specimen for analysis.

Atmospheric pressure mass spectrometric imaging of bio-tissue specimen using electrospray-assisted CW laser desorption and ionization source

2019 ◽  
Vol 14 (4) ◽  
pp. 041001
Author(s):  
Jae Young Kim ◽  
Sun Young Lee ◽  
Dae Won Moon ◽  
Ji-Won Park ◽  
Dong-Kwon Lim ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Laser Desorption ◽  
Mass Spectrometric ◽  
Tissue Specimen ◽  
Mass Spectrometric Imaging ◽  
Ionization Source ◽  
Cw Laser

1848: Revolix 70 Watt 2 Micron Continuous Wave Laser Vaporesection of the Prostate. Preliminary Results After a One Year Follow-Up

2007 ◽  
Vol 177 (4S) ◽  
pp. 614-614
Author(s):  
Thorsten Bach ◽  
Thomas R.W. Herrmann ◽  
Roman Ganzer ◽  
Andreas J. Gross
Keyword(s):  
Continuous Wave ◽  
Continuous Wave Laser ◽  
Preliminary Results ◽  
Wave Laser ◽  
One Year

scholarly journals High-precision optical fiber pressure sensor using frequency-modulated continuous-wave laser interference

AIP Advances ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 025038
Author(s):  
Lang Bai ◽  
Gang Zheng ◽  
Bin Sun ◽  
Xiongxing Zhang ◽  
Qiming Sheng ◽  
...  
Keyword(s):  
Optical Fiber ◽  
High Precision ◽  
Pressure Sensor ◽  
Continuous Wave ◽  
Continuous Wave Laser ◽  
Laser Interference ◽  
Wave Laser
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