Biocompatible Phenylboronic-Acid-Capped ZnS Nanocrystals Designed As Caps in Mesoporous Silica Hybrid Materials for on-Demand pH-Triggered Release In Cancer Cells

2018 ◽  
Vol 10 (40) ◽  
pp. 34029-34038 ◽  
Author(s):  
Yolanda Salinas ◽  
Carolin Hoerhager ◽  
Alba García-Fernández ◽  
Marina Resmini ◽  
Félix Sancenón ◽  
...  
2017 ◽  
Vol 322 ◽  
pp. 445-453 ◽  
Author(s):  
Wei Li ◽  
Tairong Kuang ◽  
Xiaoping Jiang ◽  
Jintao Yang ◽  
Ping Fan ◽  
...  

2015 ◽  
Vol 6 (18) ◽  
pp. 3529-3536 ◽  
Author(s):  
Feng Chen ◽  
Xiaoping Jiang ◽  
Tairong Kuang ◽  
Lingqian Chang ◽  
Dajiong Fu ◽  
...  

Mesoporous silica nanoparticles are modified by electrolyte polymer, giving significant ionic permselectivity under pH and/or temperature switches.


2017 ◽  
Vol 46 (24) ◽  
pp. 7878-7887 ◽  
Author(s):  
Anna M. Kaczmarek ◽  
Dolores Esquivel ◽  
Judith Ouwehand ◽  
Pascal Van Der Voort ◽  
Francisco J. Romero-Salguero ◽  
...  

A mesoporous silica and a periodic mesoporous organosilica functionalized with dipyridyl-pyridazine were grafted with Nd3+, Er3+, and Yb3+ complexes to obtain hybrid NIR emitting materials.


2003 ◽  
Vol 15 (19) ◽  
pp. 3586-3593 ◽  
Author(s):  
V. Hornebecq ◽  
Y. Mastai ◽  
M. Antonietti ◽  
S. Polarz

2015 ◽  
Vol 3 (19) ◽  
pp. 10327-10335 ◽  
Author(s):  
Xudong Zheng ◽  
Chun Wang ◽  
Jiangdong Dai ◽  
Weidong Shi ◽  
Yongsheng Yan

The importance of rare earth metals in the global economy has increased significantly in recent years due to their essential role in advanced technologies in the electronics and biomedical industries.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 858
Author(s):  
Kyriaki-Marina Lyra ◽  
Archontia Kaminari ◽  
Katerina N. Panagiotaki ◽  
Konstantinos Spyrou ◽  
Sergios Papageorgiou ◽  
...  

An efficient doxorubicin (DOX) drug delivery system with specificity against tumor cells was developed, based on multi-walled carbon nanotubes (MWCNTs) functionalized with guanidinylated dendritic molecular transporters. Acid-treated MWCNTs (oxCNTs) interacted both electrostatically and through hydrogen bonding and van der Waals attraction forces with guanidinylated derivatives of 5000 and 25,000 Da molecular weight hyperbranched polyethyleneimine (GPEI5K and GPEI25K). Chemical characterization of these GPEI-functionalized oxCNTs revealed successful decoration with GPEIs all over the oxCNTs sidewalls, which, due to the presence of guanidinium groups, gave them aqueous compatibility and, thus, exceptional colloidal stability. These GPEI-functionalized CNTs were subsequently loaded with DOX for selective anticancer activity, yielding systems of high DOX loading, up to 99.5% encapsulation efficiency, while the DOX-loaded systems exhibited pH-triggered release and higher therapeutic efficacy compared to that of free DOX. Most importantly, the oxCNTs@GPEI5K-DOX system caused high and selective toxicity against cancer cells in a non-apoptotic, fast and catastrophic manner that cancer cells cannot recover from. Therefore, the oxCNTs@GPEI5K nanocarrier was found to be a potent and efficient nanoscale DOX delivery system, exhibiting high selectivity against cancerous cells, thus constituting a promising candidate for cancer therapy.


RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 6221-6233
Author(s):  
G. Eliad Benitez-Medina ◽  
Raúl Flores ◽  
Luis Vargas ◽  
Fernando Cuenú ◽  
Pankaj Sharma ◽  
...  

Ruthenium–silica hybrid materials were synthesized. The process was tracked by FT-IR, DRS-UV-Vis, DFT and deconvolution analyses, finding experimental–theoretical correlation.


2014 ◽  
Vol 35 (9) ◽  
pp. 888-894 ◽  
Author(s):  
Renjith P. Johnson ◽  
Young-Il Jeong ◽  
Johnson V. John ◽  
Chung-Wook Chung ◽  
Seon Hee Choi ◽  
...  

2021 ◽  
Author(s):  
Yanfen Jiang ◽  
Shuqi Dong ◽  
Guoyang Qin ◽  
Li Liu ◽  
Hanying Zhao

Alkylation of thioether-containing block copolymer simultaneously incorporated sulfoniums and phenylboronic acid moieties. The co-assembly of this cationic polymer and protein generated micelles with an H2O2-and ATP-responsive release profile.


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