Folic Acid Derived Hydrogel Enhances the Survival and Promotes Therapeutic Efficacy of iPS Cells for Acute Myocardial Infarction

2018 ◽  
Vol 10 (29) ◽  
pp. 24459-24468 ◽  
Author(s):  
Hekai Li ◽  
Jie Gao ◽  
Yuna Shang ◽  
Yongquan Hua ◽  
Min Ye ◽  
...  
1995 ◽  
Vol 237 (4) ◽  
pp. 381-388 ◽  
Author(s):  
F. LANDGREN ◽  
B. ISRAELSSON ◽  
A. LINDGREN ◽  
B. HULTBERG ◽  
A. ANDERSSON ◽  
...  

2007 ◽  
Vol 99 (4) ◽  
pp. 476-481 ◽  
Author(s):  
An L. Moens ◽  
Marc J. Claeys ◽  
Floris L. Wuyts ◽  
Inge Goovaerts ◽  
Els Van Hertbruggen ◽  
...  

2021 ◽  
Vol 10 (1) ◽  
pp. 88-92
Author(s):  
Mohammed Bilal. A. Bilal ◽  
Tarig.A.M. Hamid ◽  
Makaawi A. Gadir ◽  
Mihad.M. Mahmoud

The Sudanese population has high rate of coronary artery disease (CAD). The potential association between deficiency of vitamin B12 and folic acid, in patients with acute myocardial infarction (AMI), where investigated previously with conflicted results. A case-control study was carried out involving 60 AMI patients (age 39–87 years; 40 men and 20 women) and 40 normal healthy individuals (age 39–84 years; 20 men and 20 women). Fasting venous blood samples were obtained from patients and controls. Serum was analyzed for vitamin B12 and folic acid using radio assays. The mean concentration of serum B12 and folate in AMI patients were found to be significantly lower than in controls. Vitamin B12 and folate deficiency may be considered as a risk factor for CAD development.


1970 ◽  
Vol 5 (2) ◽  
pp. 21-23
Author(s):  
MA Wahab ◽  
F Zafreen ◽  
MA Siddique ◽  
Y Akter ◽  
Z Parveen ◽  
...  

This double blind randomized placebo controlled experimental study was carried out at the department of Biochemistry and Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh over a period of one year. A total number of sixty (60) hospitalized acute myocardial infarction (AMI) patients of both sexes, age ranging 35 to 65 years, agreed after informed written consent, were included in the study. Cases were selected purposively on the basis of specified inclusion and exclusion criteria from hospitalized diagnosed patients of AMI. After detail history, clinical examination, physical and anthropometrics measurements study subjects were randomized into two groups and treated with 5 mg folic acid or placebo for 4 weeks. Fasting serum homocysteine (Hcy) and lipid profile of all the study subjects were estimated both before starting the drug and after completion of treatment, Hcy concentration was estimated by fluorescence polarization immunoassay (FPIA) method in 'AxSYM system' (Abbott, USA). Statistical analyses were done by using 'SPSS 12.0, continuous data were expressed as mean ± SEM and categorical data in percentage (%) and frequency. AMI patients Hcy concentration was higher than normal reference value (5 - 15 mmol/L). Folic acid supplementation decreased serum Hcy concentration very significantly (p<0.001) in drug group (from 25.92 ± 2.47 to 15.38 ± 0.68 mmol/L) but effect in placebo group was found no significant (p>0.05). In this study folic acid supplementation at a dose of 5 mg/day decreased Hcy concentration almost by 27%. Folic acid supplementation significantly (p<0.05) increased HDL concentration but shown no significant effect on other parameter of lipid profiles. Key words: Acute myocardial infarction (AMI), homocystein (Hcy), folic acid (Folate). DOI: 10.3329/jafmc.v5i2.4578 JAFMC Bangladesh Vol.5(2) (December) 2009, pp.21-23


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