Ultra-Sensitive Colorimetric Assay System Based on the Hybridization Chain Reaction-Triggered Enzyme Cascade Amplification

2016 ◽  
Vol 9 (1) ◽  
pp. 167-175 ◽  
Author(s):  
Shasha Lu ◽  
Tao Hu ◽  
Shuang Wang ◽  
Jian Sun ◽  
Xiurong Yang
Keyword(s):  
Colorimetric Assay ◽  
Assay System ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Enzyme Cascade ◽  
Cascade Amplification

scholarly journals Sensitive DNA detection using cascade amplification strategy based on conjugated polyelectrolytes and hybridization chain reaction

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3528-3533 ◽  
Author(s):  
Biqing Bao ◽  
Jin Zhu ◽  
Lina Gong ◽  
Jia Chen ◽  
Yanrui Pan ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Dna Detection ◽  
Hybridization Chain Reaction ◽  
Molecular Wire ◽  
Conjugated Polyelectrolytes ◽  
Chain Reaction ◽  
Amplification Strategy ◽  
Cascade Amplification

A novel cascade amplification strategy that combines the molecular wire effects of CPEs with the signal amplification capability of the HCR has been developed for sensitive DNA detection.

A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers

2017 ◽  
Vol 53 (65) ◽  
pp. 9055-9058 ◽  
Author(s):  
Jiuxing Li ◽  
Zhuangqiang Gao ◽  
Haihang Ye ◽  
Shulin Wan ◽  
Meghan Pierce ◽  
...  
Keyword(s):  
Colorimetric Assay ◽  
Detection Sensitivity ◽  
Disease Biomarkers ◽  
Enzyme Cascade ◽  
Amplification Strategy ◽  
Cascade Amplification

A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers with substantially enhanced detection sensitivity has been developed.

An enzyme-free colorimetric assay using hybridization chain reaction amplification and split aptamers

The Analyst ◽  
2015 ◽  
Vol 140 (22) ◽  
pp. 7657-7662 ◽  
Author(s):  
Qing Wang ◽  
Xiaohan Yang ◽  
Xiaohai Yang ◽  
Kemin Wang ◽  
Hua Zhang ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Colorimetric Assay ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Reaction Amplification ◽  
Amplification Strategy

A novel unmodified gold nanoparticle (AuNP)-based colorimetric assay was demonstrated based on split aptamers and the hybridization chain reaction (HCR) amplification strategy.

A label-free cyclic assembly of G-quadruplex nanowires for cascade amplification detection of T4 polynucleotide kinase activity and inhibition

The Analyst ◽  
2015 ◽  
Vol 140 (17) ◽  
pp. 6124-6130 ◽  
Author(s):  
Zhilu Shi ◽  
Xiafei Zhang ◽  
Rui Cheng ◽  
Baoxin Li ◽  
Yan Jin
Keyword(s):  
Kinase Activity ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Polynucleotide Kinase ◽  
G Quadruplex ◽  
Amplification Strategy ◽  
Cascade Amplification ◽  
T4 Polynucleotide Kinase

A label-free and enzyme-free amplification strategy has been developed for sensitively and specifically studying PNK activity and inhibitionviathe hybridization chain reaction (HCR).

A colorimetric assay for Hg(II) based on the use of a magnetic aptamer and a hybridization chain reaction

2016 ◽  
Vol 183 (11) ◽  
pp. 2855-2860 ◽  
Author(s):  
Lina Wang ◽  
Fengya Liu ◽  
Ning Sui ◽  
Manhong Liu ◽  
William W. Yu
Keyword(s):  
Colorimetric Assay ◽  
Hybridization Chain Reaction ◽  
Chain Reaction
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