scholarly journals Analyte Co-localization at Electromagnetic Gap Hot-Spots for Highly Sensitive (Bio)molecular Detection by Plasmon Enhanced Spectroscopies

2021 ◽  
Vol 13 (7) ◽  
pp. 9113-9121
Author(s):  
Rishabh Rastogi ◽  
Hamed Arianfard ◽  
David Moss ◽  
Saulius Juodkazis ◽  
Pierre-Michel Adam ◽  
...  
Keyword(s):  
Hot Spots ◽  
Molecular Detection ◽  
Highly Sensitive ◽  
Electromagnetic Gap

scholarly journals Robust plasmonic hot-spots in a metamaterial lattice for enhanced sensitivity of infrared molecular detection

2017 ◽  
Vol 111 (24) ◽  
pp. 243106 ◽  
Author(s):  
Atsushi Ishikawa ◽  
Shuhei Hara ◽  
Takuo Tanaka ◽  
Xiang Zhang ◽  
Kenji Tsuruta
Keyword(s):  
Hot Spots ◽  
Molecular Detection ◽  
Enhanced Sensitivity

scholarly journals Molecular epidemiology of mcr gene group

2020 ◽  
Vol 22 (4) ◽  
pp. 287-300
Author(s):  
Elizaveta D. Shedko ◽  
O.Yu. Timoshina ◽  
Ilya Sulejmanovich Azyzov
Keyword(s):  
Molecular Epidemiology ◽  
Plasmid Dna ◽  
Bacterial Infections ◽  
Molecular Detection ◽  
Polymyxin B ◽  
Diagnostic Tools ◽  
Drug Resistant ◽  
Gene Group ◽  
Extensively Drug Resistant ◽  
Highly Sensitive

Colistin and polymyxin B are the “last reserve” antimicrobials for the treatment of extensively drug-resistant Gram-negative bacterial infections. The rapidly increasing prevalence of polymyxin resistance mediated by the mcr gene localized on plasmid DNA currently poses a high epidemiological threat. In order to control a distribution of mcr genes, it is necessary to develop highly accurate, highly sensitive and easy-to-use diagnostic tools. This paper provides a review of the most relevant studies on the molecular epidemiology as well as current approaches to microbiological and molecular detection of mcr group genes.

A disulfur ligand stabilization approach to construct a silver(i)-cluster-based porous framework as a sensitive SERS substrate

Nanoscale ◽  
2019 ◽  
Vol 11 (35) ◽  
pp. 16293-16298 ◽  
Author(s):  
Tong Wu ◽  
Di Yin ◽  
Xun Hu ◽  
Bo Yang ◽  
Hong Liu ◽  
...  
Keyword(s):  
Hot Spots ◽  
Sers Substrate ◽  
Porosity Structure ◽  
Porous Framework ◽  
Highly Sensitive ◽  
Ligand Stabilization

An atomic-precise silver(i)-cluster-based MOF (UJN-1) stabilized by disulfur ligand has been demonstrated. Its reduced derivative exhibits highly sensitive SERS activity that can be ascribed to abundant hot spots sites and porosity structure.

Multiple coupling in plasmonic metal/dielectric hollow nanocavity arrays for highly sensitive detection

Nanoscale ◽  
2015 ◽  
Vol 7 (32) ◽  
pp. 13495-13502 ◽  
Author(s):  
Jun Yin ◽  
Yashu Zang ◽  
Chuang Yue ◽  
Xu He ◽  
Hongtao Yang ◽  
...  
Keyword(s):  
Hot Spots ◽  
Coupling Effect ◽  
Sensitive Detection ◽  
Sers Substrate ◽  
Highly Sensitive ◽  
Nanostructure Arrays ◽  
Highly Sensitive Detection

The multiple coupling effect within the plasmonic cavities and consequently generated hot spots ensure that these composite nanostructure arrays are a suitable SERS substrate for bio-sensing.

In situ formation of SERS hot spots by a bis-quaternized perylene dye: a simple strategy for highly sensitive detection of heparin over a wide concentration range

The Analyst ◽  
2018 ◽  
Vol 143 (8) ◽  
pp. 1899-1905 ◽  
Author(s):  
Wei Ji ◽  
Xue Zhang ◽  
Jianzhang Zhao ◽  
Ye Gao ◽  
Wei Song ◽  
...  
Keyword(s):  
Hot Spots ◽  
Hot Spot ◽  
Sensitive Detection ◽  
Simple Strategy ◽  
Assembly Method ◽  
Highly Sensitive ◽  
In Situ Formation ◽  
Perylene Dye ◽  
Highly Sensitive Detection

We have demonstrated a simple SERS assay for the sensitive detection of heparin by means of an in situ hot spot assembly method.

scholarly journals Ag@Au Core–Shell Porous Nanocages with Outstanding SERS Activity for Highly Sensitive SERS Immunoassay

Sensors ◽  
2019 ◽  
Vol 19 (7) ◽  
pp. 1554 ◽  
Author(s):  
Yaqi Huang ◽  
Dajie Lin ◽  
Mengting Li ◽  
Dewu Yin ◽  
Shun Wang ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Raman Spectroscopy ◽  
Hot Spots ◽  
Signal Amplification ◽  
Surface Enhanced Raman Spectroscopy ◽  
Core Shell ◽  
Chloroauric Acid ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A highly sensitive immunoassay of biomarkers has been achieved using 4-mercaptobenzoic acid-labeled Ag@Au core–shell porous nanocage tags and α-fetoprotein immuno-sensing chips. The Ag@Au porous nanocages were uniquely synthesized by using an Ag core as a self-sacrificial template and reducing agent, where the slow reaction process led to the formation of a porous Au layer. The size of the remaining Ag core and surface roughness of the Au shell were controlled by adjusting the chloroauric acid concentration. The porous cage exhibited excellent surface-enhanced Raman spectroscopy (SERS) activity, presumably due to a synergetic interaction between newly generated hot spots in the rough Au shell and the retained SERS activity of the Ag core. Using α-fetoprotein as a model analyte for immunoassay, the SERS signal had a wide linear range of 0.20 ng mL−1 to 500.0 ng mL−1 with a detection limit of 0.12 ng mL−1. Without the need of further signal amplification, the as-prepared Ag@Au bimetallic nanocages can be directly used for highly sensitive SERS assays of other biomarkers in biomedical research, diagnostics, etc.

A novel sensitive and stable surface enhanced Raman scattering substrate based on a MoS2 quantum dot/reduced graphene oxide hybrid system

2018 ◽  
Vol 6 (46) ◽  
pp. 12547-12554 ◽  
Author(s):  
Di Wu ◽  
Jianli Chen ◽  
Yaner Ruan ◽  
Kai Sun ◽  
Kehua Zhang ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Molecular Detection ◽  
Sers Substrate ◽  
Stable Surface ◽  
System P ◽  
Reduced Graphene ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A MoS2 QD/rGO nanocomposite is synthesized as a novel highly sensitive and stable surface SERS substrate for dye molecular detection.

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