scholarly journals Robust plasmonic hot-spots in a metamaterial lattice for enhanced sensitivity of infrared molecular detection

2017 ◽  
Vol 111 (24) ◽  
pp. 243106 ◽  
Author(s):  
Atsushi Ishikawa ◽  
Shuhei Hara ◽  
Takuo Tanaka ◽  
Xiang Zhang ◽  
Kenji Tsuruta
Keyword(s):  
Hot Spots ◽  
Molecular Detection ◽  
Enhanced Sensitivity

scholarly journals Molecular detection of Mycobacterium tuberculosis in poor-quality cough specimens

2020 ◽  
Vol 69 (9) ◽  
pp. 1179-1182
Author(s):  
Tondani A. Mboneni ◽  
Owen O. Eales ◽  
Ntsoaki L. Mosina ◽  
P. Bernard Fourie
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Type Species ◽  
Molecular Detection ◽  
Molecular Transport ◽  
Poor Quality ◽  
Rt Pcr ◽  
Missed Opportunities ◽  
Content Type ◽  
Clinical Specimens ◽  
Enhanced Sensitivity

Clinical specimens unfit for laboratory processing represent missed opportunities for diagnosing tuberculosis. Poor-quality cough specimens (n=61) from presumptive tuberculosis cases were cultured and GeneXpert MTB/RIF (Xpert) successfully performed on samples transferred by flocked swab into PrimeStore molecular transport medium (PS-MTM). Mycobacterium tuberculosis was grown in culture from 13 (21.3 %) and Xpert reported 15 (24.2 %) positive, of which 10 concordant. RT-PCR of PS-MTM samples showed enhanced sensitivity; three positives were missed by Xpert, five by culture and three more detected for a total of 21 positives (34.4 %).

scholarly journals Digitized molecular detection on off-the-shelf Blu-ray discs: Upgraded resolution and enhanced sensitivity

2017 ◽  
Vol 242 ◽  
pp. 79-86 ◽  
Author(s):  
Maolin Shi ◽  
Samuel S.H. Weng ◽  
Xiaochun Li ◽  
Hua-Zhong Yu
Keyword(s):  
Molecular Detection ◽  
Enhanced Sensitivity

scholarly journals Analyte Co-localization at Electromagnetic Gap Hot-Spots for Highly Sensitive (Bio)molecular Detection by Plasmon Enhanced Spectroscopies

2021 ◽  
Vol 13 (7) ◽  
pp. 9113-9121
Author(s):  
Rishabh Rastogi ◽  
Hamed Arianfard ◽  
David Moss ◽  
Saulius Juodkazis ◽  
Pierre-Michel Adam ◽  
...  
Keyword(s):  
Hot Spots ◽  
Molecular Detection ◽  
Highly Sensitive ◽  
Electromagnetic Gap

Variables affecting laboratory diagnosis of acute rickettsial infection

2018 ◽  
Vol 39 (4) ◽  
pp. 220
Author(s):  
Cecilia Kato
Keyword(s):  
Molecular Detection ◽  
False Negative ◽  
Laboratory Diagnosis ◽  
Acute Stage ◽  
Detection Methods ◽  
Rickettsial Infection ◽  
Negative Results ◽  
Enhanced Sensitivity ◽  
False Negative Results ◽  
Antibody Titres

The reference standard for the confirmation of a recent rickettsial infection is by the observation of a four-fold or greater rise in antibody titres when testing paired acute and convalescent (two to four weeks after illness resolution) sera by serological assays (Figure 1). At the acute stage of illness, diagnosis is performed by molecular detection methods most effectively on DNA extracted from tissue biopsies (eschars, skin rash, and organs) or eschar swabs. Less invasive and more convenient samples such as blood and serum may also be used for detection; however, the low number of circulating bacteria raises the possibility of false negative results. Optimal sampling practices and enhanced sensitivity must therefore be considered in order to provide a more accurate laboratory diagnosis.

scholarly journals Hierarchically Structured Plasmonic Nanoparticle Assemblies with Dual-Length Scale Electromagnetic Hot Spots for Enhanced Sensitivity in the Detection of (Bio)Molecular Analytes

2021 ◽  
Vol 125 (16) ◽  
pp. 8647-8655
Author(s):  
Rishabh Rastogi ◽  
Ekoue A. Dogbe Foli ◽  
Remi Vincent ◽  
Suresh Poovathingal ◽  
Pierre-Michel Adam ◽  
...  
Keyword(s):  
Hot Spots ◽  
Length Scale ◽  
Plasmonic Nanoparticle ◽  
Nanoparticle Assemblies ◽  
Enhanced Sensitivity

A high-performance oil-free backing pump for electron microscopes

1978 ◽  
Vol 36 (1) ◽  
pp. 110-111
Author(s):  
G.K.W. Balkau ◽  
E. Bez ◽  
J.L. Farrant
Keyword(s):  
Molecular Weight ◽  
Electron Microscope ◽  
Hot Spots ◽  
High Performance ◽  
Carbonaceous Material ◽  
Contamination Rate ◽  
Low Molecular Weight ◽  
Principal Source ◽  
Rotary Pumps ◽  
Electron Microscopes

The earliest account of the contamination of electron microscope specimens by the deposition of carbonaceous material during electron irradiation was published in 1947 by Watson who was then working in Canada. It was soon established that this carbonaceous material is formed from organic vapours, and it is now recognized that the principal source is the oil-sealed rotary pumps which provide the backing vacuum. It has been shown that the organic vapours consist of low molecular weight fragments of oil molecules which have been degraded at hot spots produced by friction between the vanes and the surfaces on which they slide. As satisfactory oil-free pumps are unavailable, it is standard electron microscope practice to reduce the partial pressure of organic vapours in the microscope in the vicinity of the specimen by using liquid-nitrogen cooled anti-contamination devices. Traps of this type are sufficient to reduce the contamination rate to about 0.1 Å per min, which is tolerable for many investigations.

Eyes and ears: Rejection and enhanced sensitivity to auditory and visual social cues

2003 ◽  
Author(s):  
Cynthia L. Pickett ◽  
Wendi L. Gardner ◽  
Megan Knowles
Keyword(s):  
Social Cues ◽  
Enhanced Sensitivity

World Bank pinpoints disaster hot spots

Nature ◽  
2005 ◽  
Author(s):  
Deirdre Lockwood
Keyword(s):  
World Bank ◽  
Hot Spots
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