Incorporation of ZnO/Bioactive Glass Nanoparticles into Alginate/Chitosan Composite Hydrogels for Wound Closure

2019 ◽  
Vol 2 (11) ◽  
pp. 5042-5052 ◽  
Author(s):  
Jiangying Zhu ◽  
Guohua Jiang ◽  
Gao Song ◽  
Tianqi Liu ◽  
Cong Cao ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Wound Closure ◽  
Composite Hydrogels ◽  
Chitosan Composite

Polyvinyl Alcohol/Chitosan Composite Hydrogels with Sustained Release of Traditional Tibetan Medicine for Promoting Chronic Diabetic Wound Healing

2021 ◽  
Author(s):  
Xingyu Chen ◽  
Zuxin Wang ◽  
Shan Gao ◽  
Wanlin Zhang ◽  
Hanwen Gong ◽  
...  
Keyword(s):  
Wound Healing ◽  
Polyvinyl Alcohol ◽  
Sustained Release ◽  
Skin Diseases ◽  
Tibetan Medicine ◽  
Diabetic Wound ◽  
Composite Hydrogels ◽  
Diabetic Wound Healing ◽  
Traditional Tibetan Medicine ◽  
Chitosan Composite

The Tibetan eighteen flavor dangshen pills (TEP) are composed of 18 traditional Tibetan medicines, which are commonly used in the treatment of skin diseases in the Tibetan medicine system. They...

Green Fabrication of Chitin/Chitosan Composite Hydrogels and Their Potential Applications

2021 ◽  
pp. 2000389
Author(s):  
Huan Xu ◽  
Li Zhang ◽  
Hongli Zhang ◽  
Jie Luo ◽  
Xiaofang Gao
Keyword(s):  
Composite Hydrogels ◽  
Potential Applications ◽  
Chitosan Composite

scholarly journals Nanohydroxyapatite Reinforced Chitosan Composite Hydrogel with Tunable Mechanical and Biological Properties for Cartilage Regeneration

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
B. Y. Santosh Kumar ◽  
Arun M. Isloor ◽  
G. C. Mohan Kumar ◽  
Inamuddin ◽  
Abdullah M. Asiri
Keyword(s):  
Cartilage Regeneration ◽  
Biological Properties ◽  
Composite Hydrogel ◽  
Time Dependent ◽  
Chitosan Hydrogel ◽  
Composite Hydrogels ◽  
Hydrogel Network ◽  
Strength And Durability ◽  
Chitosan Composite ◽  
L929 Mouse

Abstract With the continuous quest of developing hydrogel for cartilage regeneration with superior mechanobiological properties are still becoming a challenge. Chitosan (CS) hydrogels are the promising implant materials due to an analogous character of the soft tissue; however, their low mechanical strength and durability together with its lack of integrity with surrounding tissues hinder the load-bearing application. This can be solved by developing a composite chitosan hydrogel reinforced with Hydroxyapatite Nanorods (HANr). The objective of this work is to develop and characterize (physically, chemically, mechanically and biologically) the composite hydrogels loaded with different concentration of hydroxyapatite nanorod. The concentration of hydroxyapatite in the composite hydrogel was optimized and it was found that, reinforcement modifies the hydrogel network by promoting the secondary crosslinking. The compression strength could reach 1.62 ± 0.02 MPa with a significant deformation of 32% and exhibits time-dependent, rapid self-recoverable and fatigue resistant behavior based on the cyclic loading-unloading compression test. The storage modulus value can reach nearly 10 kPa which is needed for the proposed application. Besides, composite hydrogels show an excellent antimicrobial activity against Escherichia coli, Staphylococcus aureus bacteria’s and Candida albicans fungi and their cytocompatibility towards L929 mouse fibroblasts provide a potential pathway to developing a composite hydrogel for cartilage regeneration.

Forward Wound Closure with Regenerated Silk Fibroin and Polylysine-Modified Chitosan Composite Bioadhesives as Dressings

2020 ◽  
Vol 3 (11) ◽  
pp. 7941-7951
Author(s):  
Ruofan Wang ◽  
Jiangying Zhu ◽  
Guohua Jiang ◽  
Yanfang Sun ◽  
Liming Ruan ◽  
...  
Keyword(s):  
Silk Fibroin ◽  
Wound Closure ◽  
Modified Chitosan ◽  
Regenerated Silk Fibroin ◽  
Chitosan Composite

Chitosan composite hydrogels reinforced with natural clay nanotubes

2017 ◽  
Vol 175 ◽  
pp. 689-698 ◽  
Author(s):  
Biao Huang ◽  
Mingxian Liu ◽  
Changren Zhou
Keyword(s):  
Natural Clay ◽  
Composite Hydrogels ◽  
Clay Nanotubes ◽  
Chitosan Composite

Fabrication of hydroxyapatite/chitosan composite hydrogels loaded with exosomes derived from miR-126-3p overexpressed synovial mesenchymal stem cells for diabetic chronic wound healing

2016 ◽  
Vol 4 (42) ◽  
pp. 6830-6841 ◽  
Author(s):  
Min Li ◽  
Qin-Fei Ke ◽  
Shi-Cong Tao ◽  
Shang-Chun Guo ◽  
Bi-Yu Rui ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Mesenchymal Stem Cells ◽  
Chronic Wound ◽  
Wound Surface ◽  
Composite Hydrogels ◽  
Chitosan Composite

Hydroxyapatite/chitosan composite hydrogels loaded with exosomes was fabricated for promoting wound surface re-epithelialization, angiogenesis, collagen maturity and diabetic chronic wound healing.

Preparation and characterisation of laminated hydroxyapatite/chitosan composite hydrogels

2013 ◽  
Vol 43 (2) ◽  
pp. 71-75 ◽  
Author(s):  
G. F. Zuo ◽  
Y. Z. Wan ◽  
Z. J. Liu ◽  
G. J. Gao ◽  
H. D. Lun ◽  
...  
Keyword(s):  
Composite Hydrogels ◽  
Chitosan Composite
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