Green Fabrication of Chitin/Chitosan Composite Hydrogels and Their Potential Applications

2021 ◽  
pp. 2000389
Author(s):  
Huan Xu ◽  
Li Zhang ◽  
Hongli Zhang ◽  
Jie Luo ◽  
Xiaofang Gao
2021 ◽  
Author(s):  
Xingyu Chen ◽  
Zuxin Wang ◽  
Shan Gao ◽  
Wanlin Zhang ◽  
Hanwen Gong ◽  
...  

The Tibetan eighteen flavor dangshen pills (TEP) are composed of 18 traditional Tibetan medicines, which are commonly used in the treatment of skin diseases in the Tibetan medicine system. They...


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
B. Y. Santosh Kumar ◽  
Arun M. Isloor ◽  
G. C. Mohan Kumar ◽  
Inamuddin ◽  
Abdullah M. Asiri

Abstract With the continuous quest of developing hydrogel for cartilage regeneration with superior mechanobiological properties are still becoming a challenge. Chitosan (CS) hydrogels are the promising implant materials due to an analogous character of the soft tissue; however, their low mechanical strength and durability together with its lack of integrity with surrounding tissues hinder the load-bearing application. This can be solved by developing a composite chitosan hydrogel reinforced with Hydroxyapatite Nanorods (HANr). The objective of this work is to develop and characterize (physically, chemically, mechanically and biologically) the composite hydrogels loaded with different concentration of hydroxyapatite nanorod. The concentration of hydroxyapatite in the composite hydrogel was optimized and it was found that, reinforcement modifies the hydrogel network by promoting the secondary crosslinking. The compression strength could reach 1.62 ± 0.02 MPa with a significant deformation of 32% and exhibits time-dependent, rapid self-recoverable and fatigue resistant behavior based on the cyclic loading-unloading compression test. The storage modulus value can reach nearly 10 kPa which is needed for the proposed application. Besides, composite hydrogels show an excellent antimicrobial activity against Escherichia coli, Staphylococcus aureus bacteria’s and Candida albicans fungi and their cytocompatibility towards L929 mouse fibroblasts provide a potential pathway to developing a composite hydrogel for cartilage regeneration.


2019 ◽  
Vol 2 (11) ◽  
pp. 5042-5052 ◽  
Author(s):  
Jiangying Zhu ◽  
Guohua Jiang ◽  
Gao Song ◽  
Tianqi Liu ◽  
Cong Cao ◽  
...  

2017 ◽  
Vol 175 ◽  
pp. 689-698 ◽  
Author(s):  
Biao Huang ◽  
Mingxian Liu ◽  
Changren Zhou

2016 ◽  
Vol 4 (42) ◽  
pp. 6830-6841 ◽  
Author(s):  
Min Li ◽  
Qin-Fei Ke ◽  
Shi-Cong Tao ◽  
Shang-Chun Guo ◽  
Bi-Yu Rui ◽  
...  

Hydroxyapatite/chitosan composite hydrogels loaded with exosomes was fabricated for promoting wound surface re-epithelialization, angiogenesis, collagen maturity and diabetic chronic wound healing.


2013 ◽  
Vol 43 (2) ◽  
pp. 71-75 ◽  
Author(s):  
G. F. Zuo ◽  
Y. Z. Wan ◽  
Z. J. Liu ◽  
G. J. Gao ◽  
H. D. Lun ◽  
...  

RSC Advances ◽  
2020 ◽  
Vol 10 (18) ◽  
pp. 10546-10551 ◽  
Author(s):  
Juanjuan Yin ◽  
Qingqing Liu ◽  
Jingxin Zhou ◽  
Lexin Zhang ◽  
Qingrui Zhang ◽  
...  

New functional components-doped conductive polypyrrole composite hydrogels are prepared via a self-assembled process, demonstrating potential applications in catalysis as well as electrochemical materials.


RSC Advances ◽  
2020 ◽  
Vol 10 (26) ◽  
pp. 15091-15097 ◽  
Author(s):  
Lei Ge ◽  
Meng Zhang ◽  
Ran Wang ◽  
Na Li ◽  
Lexin Zhang ◽  
...  

New functional CS/GA/RGO/Pd composite hydrogels are prepared via a self-assembly process, demonstrating potential applications in catalysis as well as composite materials.


Cellulose ◽  
2018 ◽  
Vol 25 (3) ◽  
pp. 1987-1996 ◽  
Author(s):  
Meng He ◽  
Hao Chen ◽  
Xinjiang Zhang ◽  
Chengshuang Wang ◽  
Cheng Xu ◽  
...  

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