scholarly journals Bioactive glass–chitosan composite coatings on PEEK: Effects of surface wettability and roughness on the interfacial fracture resistance and in vitro cell response

2018 ◽  
Vol 440 ◽  
pp. 514-523 ◽  
Author(s):  
Wei Hong ◽  
Fangwei Guo ◽  
Jianwei Chen ◽  
Xin Wang ◽  
Xiaofeng Zhao ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Cell Response ◽  
Fracture Resistance ◽  
Composite Coatings ◽  
Interfacial Fracture ◽  
Surface Wettability ◽  
Chitosan Composite

scholarly journals Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 34
Author(s):  
Shaher Bano ◽  
Memoona Akhtar ◽  
Muhammad Yasir ◽  
Muhammad Salman Maqbool ◽  
Akbar Niaz ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Bone Diseases ◽  
Osteogenic Potential ◽  
Diffusion Method ◽  
Charge Composition ◽  
In Vitro Bioactivity ◽  
Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two-ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in vitro bioactivity. The Ag-Sr MBGNs synthesized in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

scholarly journals Development and Characterization of Bioactive Glass Containing Composite Coatings with Ion Releasing Function for Antibiotic-Free Antibacterial Surgical Sutures

Materials ◽  
2019 ◽  
Vol 12 (3) ◽  
pp. 423 ◽  
Author(s):  
Francesca Ciraldo ◽  
Kristin Schnepf ◽  
Wolfgang Goldmann ◽  
Aldo Boccaccini
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Dip Coating ◽  
Carbonate Apatite ◽  
Polymeric Layer ◽  
Surgical Sutures ◽  
Dip Coating Technique ◽  
Doped Glass

Resorbable (Vicryl® Plus) sutures were coated with zinc-doped glass (Zn-BG) and silver-doped ordered mesoporous bioactive glass (Ag-MBG) particles by a dip coating technique. A multilayer approach was used to achieve robust coatings. The first coating was a polymeric layer (e.g., PCL or chitosan) and the second one was a composite made of BG particles in a polymer matrix. The coatings were characterized in terms of morphology by scanning electron microscopy (SEM), in vitro bioactivity, and antibacterial properties. Chitosan/Ag-MBG coatings showed the ability to form hydroxyl-carbonate-apatite on their surfaces after immersion in SBF. An antibacterial effect against Gram (+) and Gram (-) bacteria was confirmed, highlighting the potential application of the coated sutures for antibiotic-free approaches.

scholarly journals Zein/Bioactive Glass Coatings with Controlled Degradation of Magnesium under Physiological Conditions: Designed for Orthopedic Implants

Prosthesis ◽  
2020 ◽  
Vol 2 (3) ◽  
pp. 211-224 ◽  
Author(s):  
Muhammad Atiq Ur Rehman
Keyword(s):  
Bioactive Glass ◽  
Electrochemical Impedance ◽  
Composite Coatings ◽  
Orthopedic Implants ◽  
Open Circuit ◽  
Practical Application ◽  
Binding Ability ◽  
Physiological Conditions ◽  
Biomedical Device

Magnesium and its alloys are widely considered as temporary bio-implants owing to their mechanical properties and biocompatibility. However, the high corrosion rates and degradation in the physiological environment restrict the practical application of Mg as a biomedical device. Therefore, in this study, Zein/45S5 bioactive glass (BG) coatings were deposited via electrophoretic deposition (EPD) on pretreated pure magnesium (Mg) substrates, which controls the rapid degradation of magnesium. The set of EPD parameters was first optimized on stainless steel (SS) and then the optimum EPD parameters were applied to obtain zein/BG composite coatings on Mg substrates. The morphology of the obtained coatings was studied by scanning electron microscopy (SEM). SEM results showed that both zein and BG were successfully deposited on the surface of the Mg substrate. Electrochemical measurements consisting of open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), and potentiodynamic polarization confirmed that the corrosion resistance of Mg improved after the deposition of zein/BG coatings. The in-vitro bioactivity study was carried out by immersing the zein/BG coatings in simulated body fluid for 3, 7, and 21 days. SEM, energy dispersive X-ray spectroscopy (EDX), and Fourier transform infrared spectroscopy results elucidated that the hydroxyapatite layer developed after 21 days of immersion in SBF, which confirmed the bone binding ability of the coatings.

scholarly journals Electrophoretic Deposition of Gentamicin-Loaded Bioactive Glass/Chitosan Composite Coatings for Orthopaedic Implants

2014 ◽  
Vol 6 (11) ◽  
pp. 8796-8806 ◽  
Author(s):  
Fatemehsadat Pishbin ◽  
Viviana Mouriño ◽  
Sabrina Flor ◽  
Stefan Kreppel ◽  
Vehid Salih ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Electrophoretic Deposition ◽  
Composite Coatings ◽  
Orthopaedic Implants ◽  
Chitosan Composite

scholarly journals Synthesis and Characterization of Silver–Strontium (Ag-Sr) Doped Mesoporous Bioactive Glass Nanoparticles

2021 ◽  
Author(s):  
Shaher Bano ◽  
Memoona Akhtar ◽  
Muhammad Yasir ◽  
Muhammad Salman Maqbool ◽  
Akbar Niaz ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Bone Diseases ◽  
Osteogenic Potential ◽  
Diffusion Method ◽  
Charge Composition ◽  
In Vitro Bioactivity ◽  
Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc. are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag) and strontium (Sr) doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ & Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in-vitro bioactivity. The Ag-Sr MBGNs synthesize in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

In vitro study of polycaprolactone/bioactive glass composite coatings on corrosion and bioactivity of pure Mg

2015 ◽  
Vol 355 ◽  
pp. 832-841 ◽  
Author(s):  
Yuyun Yang ◽  
Carolin Michalczyk ◽  
Ferdinand Singer ◽  
Sannakaisa Virtanen ◽  
Aldo R. Boccaccini
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
In Vitro Study ◽  
Vitro Study ◽  
Glass Composite

scholarly journals In vitro endothelial cell response to ionic dissolution products from boron-doped bioactive glass in the SiO2–CaO–P2O5–Na2O system

2014 ◽  
Vol 2 (43) ◽  
pp. 7620-7630 ◽  
Author(s):  
Luis A. Haro Durand ◽  
Adrián Góngora ◽  
José M. Porto López ◽  
Aldo R. Boccaccini ◽  
M. Paola Zago ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Regenerative Medicine ◽  
Bioactive Glass ◽  
Cell Response ◽  
Bioactive Glasses ◽  
Therapeutic Alternative ◽  
Boron Doped ◽  
System P ◽  
Endothelial Cell Response

As it has been established that boron (B) may perform functions in angiogenesis and osteogenesis, the controlled and localized release of B ions from bioactive glasses (BGs) is expected to provide a promising therapeutic alternative for regenerative medicine of vascularized tissues, such as bone.

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