scholarly journals New Class of Homoleptic and Heteroleptic Bis(terpyridine) Iridium(III) Complexes with Strong Photodynamic Therapy Effects

2019 ◽  
Vol 2 (7) ◽  
pp. 2964-2977 ◽  
Author(s):  
Bingqing Liu ◽  
Susan Monro ◽  
Zhike Li ◽  
Mohammed A. Jabed ◽  
Daniel Ramirez ◽  
...  
RSC Advances ◽  
2017 ◽  
Vol 7 (54) ◽  
pp. 34160-34169 ◽  
Author(s):  
Leila Tabrizi ◽  
Hossein Chiniforoshan

A new class of cyclometalated iridium(iii) with NCN pincer andmeso-phenylcyanamide BODIPY ligands has been synthesized and studied for photodynamic therapy.


2017 ◽  
Vol 53 (12) ◽  
pp. 2009-2012 ◽  
Author(s):  
Jordan Atchison ◽  
Sukanta Kamila ◽  
Heather Nesbitt ◽  
Kieran A. Logan ◽  
Dean M Nicholas ◽  
...  

Iodinated cyanine dye 6a has been developed for use as a NIR excited photosensitiser in photodynamic therapy.


2002 ◽  
Vol 06 (02) ◽  
pp. 130-134 ◽  
Author(s):  
François Lamarche ◽  
Vincent Sol ◽  
Yi-Ming Huang ◽  
Robert Granet ◽  
Michel Guilloton ◽  
...  

A new class of porphyrins bearing natural polyamines has been designed in order to target the photosensitizers towards malignant cells. We report here the synthesis of spermidine and spermine porphyrins. The photocytotoxicity of these compounds against K562 human chronic myelogenous leukemia cells has been evaluated and compared to Photofrin II®.


1996 ◽  
Vol 74 (8) ◽  
pp. 1550-1563 ◽  
Author(s):  
Khalid Driaf ◽  
Robert Granet ◽  
Pierre krausz ◽  
Mourad Kaouadji ◽  
Bernard Verneuil ◽  
...  

Trisalkylpyridinium porphyrins substituted by one glycosyl (glucosyl, maltosyl, and lactosyl) moiety have been prepared in acceptable yields. These glycosylated cationic porphyrins have been synthesized from pyrrole condensed with 4-pyridinecarboxaldehyde, and suitable ortho- or para peracetylglycosyloxybenzaldehyde derivatives in refluxing propionic acid –Ac2O followed by action of alkyliodide in DMF. Deprotection of the glycosylated moieties led to a new class of representative glycosylated porphyrins. Key words: porphyrins, cationic, glycosylated; phototherapy, cancer.


2016 ◽  
Vol 52 (13) ◽  
pp. 2705-2708 ◽  
Author(s):  
Roberto Padilla ◽  
José A. Rodriguez-Corrales ◽  
Lauren E. Donohoe ◽  
Brenda S. J. Winkel ◽  
Karen J. Brewer

Appending anthracene units to [(bpy)2Ru(dpp)]2+ results in Ru(ii) agents that exhibit dynamic photoreactivity towards DNA and protein.


RSC Advances ◽  
2018 ◽  
Vol 8 (19) ◽  
pp. 10310-10313 ◽  
Author(s):  
Elene C. Pereira-Maia ◽  
Ivina P. Souza ◽  
Kelen J. R. C. Nunes ◽  
Alexandre A. Castro ◽  
Teodorico C. Ramalho ◽  
...  

A new class of polyoxoniobate complex has been synthesized and characterized as a novel anticancer agent for photodynamic therapy.


2001 ◽  
pp. 2596-2597 ◽  
Author(s):  
Frieder Mitzel ◽  
Simon FitzGerald ◽  
Andrew Beeby ◽  
Rüdiger Faust

ACS Omega ◽  
2020 ◽  
Vol 5 (18) ◽  
pp. 10596-10601 ◽  
Author(s):  
Rune F. Einrem ◽  
Abraham B. Alemayehu ◽  
Sergey M. Borisov ◽  
Abhik Ghosh ◽  
Odrun A. Gederaas

2020 ◽  
Vol 11 (44) ◽  
pp. 12047-12069
Author(s):  
Deborah A. Smithen ◽  
Susan Monro ◽  
Mitch Pinto ◽  
John Roque ◽  
Roberto M. Diaz-Rodriguez ◽  
...  

Ten dinuclear Ru(ii) complexes based on the bis[pyrrolyl Ru(ii)] triad scaffold were prepared to evaluate the influence of the central organic linker on the spectroscopic and in vitro photodynamic therapy (PDT) properties of the compounds.


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