Construction of Hybrid Cell Spheroids Using Cell-Sized Cross-Linked Nanogel Microspheres as an Artificial Extracellular Matrix

2021 ◽  
Author(s):  
Shunya Hayashi ◽  
Yoshihiro Sasaki ◽  
Hirotaka Kubo ◽  
Shin-ichi Sawada ◽  
Naoya Kinoshita ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Hybrid Cell ◽  
Cell Spheroids ◽  
Artificial Extracellular Matrix

scholarly journals Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering

Nanomaterials ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 21
Author(s):  
Mina Keshvardoostchokami ◽  
Sara Seidelin Majidi ◽  
Peipei Huo ◽  
Rajan Ramachandran ◽  
Menglin Chen ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Polymer Composite ◽  
Electrospun Nanofibers ◽  
Synthetic Polymer ◽  
Inorganic Materials ◽  
Host Cells ◽  
Natural Polymer ◽  
Reinforced Polymers ◽  
Nanofibrous Scaffolds ◽  
Artificial Extracellular Matrix

Many types of polymer nanofibers have been introduced as artificial extracellular matrices. Their controllable properties, such as wettability, surface charge, transparency, elasticity, porosity and surface to volume proportion, have attracted much attention. Moreover, functionalizing polymers with other bioactive components could enable the engineering of microenvironments to host cells for regenerative medical applications. In the current brief review, we focus on the most recently cited electrospun nanofibrous polymeric scaffolds and divide them into five main categories: natural polymer-natural polymer composite, natural polymer-synthetic polymer composite, synthetic polymer-synthetic polymer composite, crosslinked polymers and reinforced polymers with inorganic materials. Then, we focus on their physiochemical, biological and mechanical features and discussed the capability and efficiency of the nanofibrous scaffolds to function as the extracellular matrix to support cellular function.

Promotion of Angiogenesis by an Artificial Extracellular Matrix Protein Containing the Laminin-1-Derived IKVAV Sequence

2009 ◽  
Vol 20 (9) ◽  
pp. 1759-1764 ◽  
Author(s):  
Makiko Nakamura ◽  
Kumiko Yamaguchi ◽  
Masayasu Mie ◽  
Makoto Nakamura ◽  
Keiichi Akita ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Protein ◽  
Extracellular Matrix Protein ◽  
Artificial Extracellular Matrix ◽  
Laminin 1

Transformable Nanomaterials as an Artificial Extracellular Matrix for Inhibiting Tumor Invasion and Metastasis

ACS Nano ◽  
2017 ◽  
Vol 11 (4) ◽  
pp. 4086-4096 ◽  
Author(s):  
Xiao-Xue Hu ◽  
Ping-Ping He ◽  
Guo-Bin Qi ◽  
Yu-Juan Gao ◽  
Yao-Xin Lin ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Tumor Invasion ◽  
Invasion And Metastasis ◽  
Artificial Extracellular Matrix

A fusion protein N-cadherin-Fc as an artificial extracellular matrix surface for maintenance of stem cell features

Biomaterials ◽  
2010 ◽  
Vol 31 (20) ◽  
pp. 5287-5296 ◽  
Author(s):  
Xiao-Shan Yue ◽  
Yuta Murakami ◽  
Toshiyuki Tamai ◽  
Masato Nagaoka ◽  
Chong-Su Cho ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Fusion Protein ◽  
Matrix Surface ◽  
Artificial Extracellular Matrix

Cell adhesion on an artificial extracellular matrix using aptamer-functionalized PEG hydrogels

Biomaterials ◽  
2012 ◽  
Vol 33 (5) ◽  
pp. 1353-1362 ◽  
Author(s):  
Niancao Chen ◽  
Zhaoyang Zhang ◽  
Boonchoy Soontornworajit ◽  
Jing Zhou ◽  
Yong Wang
Keyword(s):  
Extracellular Matrix ◽  
Cell Adhesion ◽  
Peg Hydrogels ◽  
Artificial Extracellular Matrix

Fabrication of BSA Loaded Poly(Caprolactone) (PCL) Microsphere Incorporated Chitosan Scaffolds for Tissues Engineering Application

2014 ◽  
Vol 695 ◽  
pp. 199-202
Author(s):  
Mad Jin Rashid ◽  
Lari Ali Reza ◽  
Naznin Sultana
Keyword(s):  
Extracellular Matrix ◽  
Engineering Application ◽  
Chitosan Solution ◽  
Living Cells ◽  
Porous Scaffolds ◽  
High Porosity ◽  
Chitosan Scaffolds ◽  
Artificial Extracellular Matrix ◽  
Poly Caprolactone ◽  
Suitable Environment

Scaffolds-based tissues engineering involves the combination of an artificial extracellular matrix (ECM), living cells, with high porosity and well connected pores that will provide suitable environment for cells. In this study, firstly, poly (caprolactone) (PCL)-based microspheres were synthesized and characterized. Bovine serum albumin (BSA) (0.04% w/v) was added into the microspheres produced from 5% (w/v) PCL concentration. BSA loaded microspheres were then incorporated into chitosan solution to fabricate porous scaffolds. The scaffolds were then characterized using different techniques.

Sign in / Sign up

Export Citation Format

Share Document