Metal-Free Site-Specific Hydroxyalkylation of Imidazo[1,2-a]pyridines with Alcohols through Radical Reaction

2019 ◽  
Vol 21 (9) ◽  
pp. 3436-3440 ◽  
Author(s):  
Shengzhou Jin ◽  
Bo Xie ◽  
Sen Lin ◽  
Cong Min ◽  
Ruihong Deng ◽  
...  
Keyword(s):  
Radical Reaction ◽  
Site Specific ◽  
Metal Free

A Synthetic Method for Site‐Specific Functionalized Polypeptides: Metal‐Free, Highly Active, and Selective at Room Temperature

2020 ◽  
Vol 60 (2) ◽  
pp. 889-895
Author(s):  
Wei Zhao ◽  
Yanfeng Lv ◽  
Ji Li ◽  
Zihao Feng ◽  
Yonghao Ni ◽  
...  
Keyword(s):  
Room Temperature ◽  
Synthetic Method ◽  
Site Specific ◽  
Metal Free ◽  
Highly Active

A mild, general, and metal-free method for site-specific deuteration induced by visible light using D2O as the source of deuterium atoms

2020 ◽  
Vol 22 (3) ◽  
pp. 669-672 ◽  
Author(s):  
Shuai Shi ◽  
Ruining Li ◽  
Liangming Rao ◽  
Zhankui Sun
Keyword(s):  
Visible Light ◽  
Functional Group ◽  
Site Specific ◽  
Metal Free ◽  
Mild Conditions ◽  
Highly Efficient ◽  
Radical Approach

Visible light induced desulfurization–deuteration method was developed using D2O as the source of deuterium atoms. This radical approach features mild conditions, broad substrate scope, highly efficient D-incorporation and excellent functional group compatibility.

Peroxide-mediated site-specific C–H methylation of imidazo[1,2-a]pyridines and quinoxalin-2(1H)-ones under metal-free conditions

2020 ◽  
Vol 18 (2) ◽  
pp. 205-210 ◽  
Author(s):  
Shengzhou Jin ◽  
Hua Yao ◽  
Sen Lin ◽  
Xiaoqing You ◽  
Yao Yang ◽  
...  
Keyword(s):  
Site Specific ◽  
Metal Free

An effective approach to realize the direct methylation of imidazo[1,2-a]pyridines and quinoxalin-2(1H)-ones with peroxides under metal-free conditions is described.

scholarly journals A Synthetic Method for Site‐Specific Functionalized Polypeptides: Metal‐Free, Highly Active, and Selective at Room Temperature

2020 ◽  
Vol 133 (2) ◽  
pp. 902-908
Author(s):  
Wei Zhao ◽  
Yanfeng Lv ◽  
Ji Li ◽  
Zihao Feng ◽  
Yonghao Ni ◽  
...  
Keyword(s):  
Room Temperature ◽  
Synthetic Method ◽  
Site Specific ◽  
Metal Free ◽  
Highly Active

An Easy Access to Sulfur Derivatives of 6,8-Dioxabicyclo[3.2.1]octanes, Naturally Abundant Scaffolds

Synthesis ◽  
2018 ◽  
Vol 50 (13) ◽  
pp. 2624-2630 ◽  
Author(s):  
Elena Schmidt ◽  
Ivan Bidusenko ◽  
Igor Ushakov ◽  
Nadezhda Protsuk ◽  
Boris Trofimov
Keyword(s):  
Natural Products ◽  
Free Radical ◽  
Transition Metal ◽  
Uv Irradiation ◽  
Radical Reaction ◽  
Easy Access ◽  
Free Radical Reaction ◽  
One Pot ◽  
Metal Free ◽  
Derivatives Of

Sulfur derivatives of 6,8-dioxabicyclo[3.2.1]octanes related to a number of natural products have been synthesized by the click hydrothiolation (AIBN or UV irradiation) of 7-methylene-6,8-dioxabicy­clo[3.2.1]octanes, assembled from acetylene and ketones in a one-pot transition-metal-free synthetic operation. An unusual feature of this free-radical reaction is that it is accelerated in the presence of bases due to involvement of the latter in a competition between the thiol addition and proton-catalyzed isomerization of the starting bicyclooctanes.

Site-specific hydroxyalkylation of chromones via alcohol mediated Minisci-type radical conjugate addition

2018 ◽  
Vol 16 (11) ◽  
pp. 1823-1827 ◽  
Author(s):  
Rongzhen Chen ◽  
Jin-Tao Yu ◽  
Jiang Cheng
Keyword(s):  
Conjugate Addition ◽  
Site Specific ◽  
Metal Free ◽  
Type Radical

The metal-free C2-functionalization of chromones with alcohols and ethers via radical sp3 C–H activation was developed.

Site-Specific Cleavage of RNA by a Metal-Free Artificial Nuclease Attached to Antisense Oligonucleotides

2006 ◽  
Vol 128 (24) ◽  
pp. 8063-8067 ◽  
Author(s):  
Claudio Gnaccarini ◽  
Sascha Peter ◽  
Ute Scheffer ◽  
Stefan Vonhoff ◽  
Sven Klussmann ◽  
...  
Keyword(s):  
Antisense Oligonucleotides ◽  
Site Specific ◽  
Metal Free ◽  
Artificial Nuclease

Stepwise photosensitized C(sp3)–C(CO) bond cleavage and C–P bond formation of 1,3-dicarbonyls with arylphosphine oxides

2019 ◽  
Vol 6 (9) ◽  
pp. 1433-1437 ◽  
Author(s):  
Xiuli Zhao ◽  
Mengmeng Huang ◽  
Yabo Li ◽  
Jianye Zhang ◽  
Jung Keun Kim ◽  
...  
Keyword(s):  
Visible Light ◽  
Bond Cleavage ◽  
Bond Formation ◽  
Radical Reaction ◽  
Metal Free

A visible-light-induced metal-free cascade radical reaction of chemoselective C–C bond cleavage with a C–P bond formation was discovered to obtain β-ketophosphine oxides.

Sign in / Sign up

Export Citation Format

Share Document