Crystal Engineering of Multicomponent Crystal Forms of p-Aminosalicylic Acid with Pyridine Based Coformers

2016 ◽  
Vol 16 (3) ◽  
pp. 1268-1281 ◽  
Author(s):  
Pramod Kumar Goswami ◽  
Ram Thaimattam ◽  
Arunachalam Ramanan
Keyword(s):  
Crystal Engineering ◽  
Aminosalicylic Acid ◽  
Crystal Forms

Crystal Engineering of Isostructural Quaternary Multicomponent Crystal Forms of Olanzapine

2012 ◽  
Vol 12 (8) ◽  
pp. 4194-4201 ◽  
Author(s):  
Heather D. Clarke ◽  
Magali B. Hickey ◽  
Brian Moulton ◽  
Jason A. Perman ◽  
Matthew L. Peterson ◽  
...  
Keyword(s):  
Crystal Engineering ◽  
Crystal Forms

Expanding the Pool of Multicomponent Crystal Forms of the Antibiotic 4-Aminosalicylic Acid: The Influence of Crystallization Conditions

2017 ◽  
Vol 17 (12) ◽  
pp. 6417-6425 ◽  
Author(s):  
Vânia André ◽  
Oleksii Shemchuk ◽  
Fabrizia Grepioni ◽  
Dario Braga ◽  
M. Teresa Duarte
Keyword(s):  
Aminosalicylic Acid ◽  
Crystal Forms ◽  
Influence Of Crystallization ◽  
Crystallization Conditions

Multiple Crystal Forms of p-Aminosalicylic Acid: Salts, Salt Co-Crystal Hydrate, Co-Crystals, and Co-Crystal Polymorphs

2012 ◽  
Vol 13 (1) ◽  
pp. 360-366 ◽  
Author(s):  
Pramod Kumar Goswami ◽  
Ram Thaimattam ◽  
Arunachalam Ramanan
Keyword(s):  
Crystal Hydrate ◽  
Aminosalicylic Acid ◽  
Crystal Forms ◽  
Acid Salts

scholarly journals New crystal forms of the antibiotic 4-aminosalicylic acid

2009 ◽  
Vol 65 (a1) ◽  
pp. s300-s301 ◽  
Author(s):  
Vânia André ◽  
Dario Braga ◽  
Fabrizia Grepioni ◽  
Maria Teresa Duarte
Keyword(s):  
Aminosalicylic Acid ◽  
Crystal Forms

scholarly journals Crystal engineering of multicomponent crystal forms of antituberculosis drugs

2017 ◽  
Vol 73 (a2) ◽  
pp. C207-C207
Author(s):  
Javier Ellena ◽  
Luan Farinelli Diniz ◽  
Cristiane Cabral de Melo ◽  
Paulo de Sousa Carvalho Jr
Keyword(s):  
Crystal Engineering ◽  
Antituberculosis Drugs ◽  
Crystal Forms

Crystal Forms of the Antibiotic 4-Aminosalicylic Acid: Solvates and Molecular Salts with Dioxane, Morpholine, and Piperazine

2009 ◽  
Vol 9 (12) ◽  
pp. 5108-5116 ◽  
Author(s):  
Vânia André ◽  
Dario Braga ◽  
Fabrizia Grepioni ◽  
M. Teresa Duarte
Keyword(s):  
Aminosalicylic Acid ◽  
Crystal Forms ◽  
Molecular Salts

scholarly journals Mechanochemistry in Portugal—A Step towards Sustainable Chemical Synthesis

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 241
Author(s):  
Vânia André ◽  
M. Teresa Duarte ◽  
Clara S. B. Gomes ◽  
Mafalda C. Sarraguça
Keyword(s):  
Crystal Engineering ◽  
Solid Dispersions ◽  
Amorphous Solid ◽  
Inorganic Synthesis ◽  
Crystal Forms ◽  
Crystalline Materials ◽  
Pharmaceutical Ingredients ◽  
Research Areas ◽  
Metal Organic ◽  
Synthesized Materials

In Portugal, publications with mechanochemical methods date back to 2009, with the report on mechanochemical strategies for the synthesis of metallopharmaceuticals. Since then, mechanochemical applications have grown in Portugal, spanning several fields, mainly crystal engineering and supramolecular chemistry, catalysis, and organic and inorganic chemistry. The area with the most increased development is the synthesis of multicomponent crystal forms, with several groups synthesizing solvates, salts, and cocrystals in which the main objective was to improve physical properties of the active pharmaceutical ingredients. Recently, non-crystalline materials, such as ionic liquids and amorphous solid dispersions, have also been studied using mechanochemical methods. An area that is in expansion is the use of mechanochemical synthesis of bioinspired metal-organic frameworks with an emphasis in antibiotic coordination frameworks. The use of mechanochemistry for catalysis and organic and inorganic synthesis has also grown due to the synthetic advantages, ease of synthesis, scalability, sustainability, and, in the majority of cases, the superior properties of the synthesized materials. It can be easily concluded that mechanochemistry is expanding in Portugal in diverse research areas.

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