Gold Nanoparticle Translocation Dynamics and Electrical Detection of Single Particle Diffusion Using Solid-State Nanopores

2013 ◽  
Vol 85 (17) ◽  
pp. 8180-8187 ◽  
Author(s):  
Gaurav Goyal ◽  
Kevin J. Freedman ◽  
Min Jun Kim
Nanoscale ◽  
2016 ◽  
Vol 8 (32) ◽  
pp. 14925-14931 ◽  
Author(s):  
Akifumi Horio ◽  
Tsuneaki Sakurai ◽  
G. B. V. S. Lakshmi ◽  
Devesh Kumar Avasthi ◽  
Masaki Sugimoto ◽  
...  

2020 ◽  
Author(s):  
Richard W. Taylor ◽  
Cornelia Holler ◽  
Reza Gholami Mahmoodabadi ◽  
Michelle Küppers ◽  
Houman Mirzaalian Dastjerdi ◽  
...  

The mobility of proteins and lipids within the cell, sculpted oftentimes by the organisation of the membrane, reveals a great wealth of information on the function and interaction of these molecules as well as the membrane itself. Single particle tracking has proven to be a vital tool to study the mobility of individual molecules and unravel details of their behaviour. Interferometric scattering (iSCAT) microscopy is an emerging technique well suited for visualising the diffusion of gold nanoparticle-labelled membrane proteins to a spatial and temporal resolution beyond the means of traditional fluorescent labels. We discuss the applicability of interferometric single particle tracking (iSPT) microscopy to investigate the minutia in the motion of a protein through measurements visualising the mobility of the epidermal growth factor receptor in various biological scenarios on the live cell.


2013 ◽  
Vol 176 ◽  
pp. 368-373 ◽  
Author(s):  
Christian Leiterer ◽  
Steffen Berg ◽  
Antti-Pekka Eskelinen ◽  
Andrea Csaki ◽  
Matthias Urban ◽  
...  

The Analyst ◽  
2011 ◽  
Vol 136 (20) ◽  
pp. 4247 ◽  
Author(s):  
Tao Lan ◽  
Chaoqing Dong ◽  
Xiangyi Huang ◽  
Jicun Ren

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