Triple Signal Amplification of Graphene Film, Polybead Carried Gold Nanoparticles as Tracing Tag and Silver Deposition for Ultrasensitive Electrochemical Immunosensing

2012 ◽  
Vol 84 (8) ◽  
pp. 3662-3668 ◽  
Author(s):  
Dajie Lin ◽  
Jie Wu ◽  
Min Wang ◽  
Feng Yan ◽  
Huangxian Ju
The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.


2011 ◽  
Vol 123 (10) ◽  
pp. 2355-2360 ◽  
Author(s):  
Renato Bonomi ◽  
Alessandro Cazzolaro ◽  
Anna Sansone ◽  
Paolo Scrimin ◽  
Leonard J. Prins

2014 ◽  
Vol 6 (7) ◽  
pp. 2221-2226 ◽  
Author(s):  
Xiao-Yan Li ◽  
Zi Yi ◽  
Hao Tang ◽  
Xia Chu ◽  
Ru-Qin Yu

Highly sensitive electrochemical immune analysis was achieved based on dual signal amplification of AuNPs and telomerase extension reaction.


2014 ◽  
Vol 431 ◽  
pp. 71-76 ◽  
Author(s):  
Weihua Hu ◽  
Hongming Chen ◽  
Huanhuan Zhang ◽  
Guangli He ◽  
Xin Li ◽  
...  

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 50 ◽  
Author(s):  
Hao-Chun Chiang ◽  
Yanyan Wang ◽  
Qi Zhang ◽  
Kalle Levon

A highly sensitive electrochemical biosensor with a signal amplification platform of electrodeposited gold nanoparticle (AuNP) has been developed and characterized. The sizes of the synthesized AuNP were found to be critical for the performance of biosensor in which the sizes were dependent on HAuCl4 and acid concentrations; as well as on scan cycles and scan rates in the gold electro-reduction step. Systematic investigations of the adsorption of proteins with different sizes from aqueous electrolyte solution onto the electrodeposited AuNP surface were performed with a potentiometric method and calibrated by design of experiment (DOE). The resulting amperometric glucose biosensors was demonstrated to have a low detection limit (> 50 μM) and a wide linear range after optimization with AuNP electrodeposition.


The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Jun-Tao Cao ◽  
Xiao-Long Fu ◽  
Fu-Rao Liu ◽  
Shu-Wei Ren ◽  
Yan-Ming Liu

A novel spatial-resolved electrochemiluminescent (ECL) ratiometry for cardiac troponin I (cTnI) analysis was developed using resonance energy transfer (RET) and a coreactant consumption strategy for signal amplification.


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