Detection of Enzyme Activity through Catalytic Signal Amplification with Functionalized Gold Nanoparticles

2011 ◽  
Vol 123 (10) ◽  
pp. 2355-2360 ◽  
Author(s):  
Renato Bonomi ◽  
Alessandro Cazzolaro ◽  
Anna Sansone ◽  
Paolo Scrimin ◽  
Leonard J. Prins
Keyword(s):  
Gold Nanoparticles ◽  
Enzyme Activity ◽  
Signal Amplification ◽  
Functionalized Gold Nanoparticles

Detection of Enzyme Activity through Catalytic Signal Amplification with Functionalized Gold Nanoparticles

2011 ◽  
Vol 50 (10) ◽  
pp. 2307-2312 ◽  
Author(s):  
Renato Bonomi ◽  
Alessandro Cazzolaro ◽  
Anna Sansone ◽  
Paolo Scrimin ◽  
Leonard J. Prins
Keyword(s):  
Gold Nanoparticles ◽  
Enzyme Activity ◽  
Signal Amplification ◽  
Functionalized Gold Nanoparticles

Sensitive detection of dengue virus NS1 by highly stable affibody-functionalized gold nanoparticles

2018 ◽  
Vol 42 (15) ◽  
pp. 12607-12614 ◽  
Author(s):  
Jinho Bang ◽  
Heesun Park ◽  
Won Il Choi ◽  
Daekyung Sung ◽  
Jin Hyung Lee ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Dengue Virus ◽  
Signal Amplification ◽  
Sensitive Detection ◽  
Functionalized Gold Nanoparticles

The anti-NS1 affibody-functionalized gold nanoparticles based ELISA resulted in a 14.2-fold signal amplification performance for dengue NS1 detection.

Catalytic signal amplification for the discrimination of ATP and ADP using functionalised gold nanoparticles

2016 ◽  
Vol 14 (28) ◽  
pp. 6811-6820 ◽  
Author(s):  
Cristian Pezzato ◽  
Jack L.-Y. Chen ◽  
Patrizia Galzerano ◽  
Michela Salvi ◽  
Leonard J. Prins
Keyword(s):  
Gold Nanoparticles ◽  
Catalytic Activity ◽  
Output Signal ◽  
Signal Amplification ◽  
Functionalized Gold Nanoparticles

ATP and ADP inhibit the catalytic activity of functionalized gold nanoparticles to a different extent causing a difference in output signal.

scholarly journals Correction: Poly(adenine)-mediated DNA-functionalized gold nanoparticles for sensitive detection of mercury ions in aqueous media

RSC Advances ◽  
2021 ◽  
Vol 11 (37) ◽  
pp. 22691-22691
Author(s):  
Jinjin Yin ◽  
Jiuchao Wang ◽  
Xiyue Yang ◽  
Tao Wu ◽  
Huashan Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Aqueous Media ◽  
Sensitive Detection ◽  
Mercury Ions ◽  
Functionalized Gold Nanoparticles

Correction for ‘Poly(adenine)-mediated DNA-functionalized gold nanoparticles for sensitive detection of mercury ions in aqueous media’ by Jinjin Yin et al., RSC Adv., 2019, 9, 18728–18733, DOI: 10.1039/C9RA03041G.

Functionalized Gold Nanoparticles as Phosphorescent Nanomaterials and Sensors

2006 ◽  
Vol 128 (6) ◽  
pp. 1907-1913 ◽  
Author(s):  
Binil Itty Ipe ◽  
Karuvath Yoosaf ◽  
Kakkudiyil George Thomas
Keyword(s):  
Gold Nanoparticles ◽  
Functionalized Gold Nanoparticles

Inhibition of S. aureus‐Infection of HUVECs by Trehalose and Glucose‐functionalized Gold Nanoparticles

2021 ◽  
Author(s):  
Yimeng Li ◽  
Nicholas Ariotti ◽  
Behnaz Aghaei ◽  
Elvis Pandzic ◽  
Sylvia Ganda ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Aureus Infection ◽  
Functionalized Gold Nanoparticles

scholarly journals X-ray Fluorescence Uptake Measurement of Functionalized Gold Nanoparticles in Tumor Cell Microsamples

2021 ◽  
Vol 22 (7) ◽  
pp. 3691
Author(s):  
Oliver Schmutzler ◽  
Sebastian Graf ◽  
Nils Behm ◽  
Wael Y. Mansour ◽  
Florian Blumendorf ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Irradiation Time ◽  
High Sensitivity ◽  
Nanoparticle Uptake ◽  
X Ray ◽  
Functionalized Gold Nanoparticles ◽  
Uptake Measurement ◽  
Prostate Tumor Cells ◽  
Non Destructive

Quantitative cellular in vitro nanoparticle uptake measurements are possible with a large number of different techniques, however, all have their respective restrictions. Here, we demonstrate the application of synchrotron-based X-ray fluorescence imaging (XFI) on prostate tumor cells, which have internalized differently functionalized gold nanoparticles. Total nanoparticle uptake on the order of a few hundred picograms could be conveniently observed with microsamples consisting of only a few hundreds of cells. A comparison with mass spectroscopy quantification is provided, experimental results are both supported and sensitivity limits of this XFI approach extrapolated by Monte-Carlo simulations, yielding a minimum detectable nanoparticle mass of just 5 pg. This study demonstrates the high sensitivity level of XFI, allowing non-destructive uptake measurements with very small microsamples within just seconds of irradiation time.

Sign in / Sign up

Export Citation Format

Share Document