scholarly journals Structural Mass Spectrometry of Proteins Using Hydroxyl Radical Based Protein Footprinting

2011 ◽  
Vol 83 (19) ◽  
pp. 7234-7241 ◽  
Author(s):  
Liwen Wang ◽  
Mark R. Chance
Keyword(s):  
Mass Spectrometry ◽  
Hydroxyl Radical ◽  
Protein Footprinting ◽  
Structural Mass Spectrometry ◽  
Structural Mass

The interaction between the natural metalloendopeptidase inhibitor BJ46a and its target toxin jararhagin analyzed by structural mass spectrometry and molecular modeling

2020 ◽  
Vol 221 ◽  
pp. 103761
Author(s):  
Viviane A. Bastos ◽  
Francisco Gomes-Neto ◽  
Surza Lucia G. Rocha ◽  
André Teixeira-Ferreira ◽  
Jonas Perales ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Molecular Modeling ◽  
Structural Mass Spectrometry ◽  
Structural Mass

The growing role of structural mass spectrometry in the discovery and development of therapeutic antibodies

The Analyst ◽  
2018 ◽  
Vol 143 (11) ◽  
pp. 2459-2468 ◽  
Author(s):  
Yuwei Tian ◽  
Brandon T. Ruotolo
Keyword(s):  
Mass Spectrometry ◽  
State Of The Art ◽  
Therapeutic Antibodies ◽  
Critical Importance ◽  
Current State ◽  
Measurement Science ◽  
Structural Mass Spectrometry ◽  
Structural Mass

The comprehensive structural characterization of therapeutic antibodies is of critical importance for the successful discovery and development of such biopharmaceuticals, yet poses many challenges to modern measurement science. Here, we review the current state-of-the-art mass spectrometry technologies focusing on the characterization of antibody-based therapeutics.

scholarly journals Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases

2014 ◽  
Vol 10 (11) ◽  
pp. 2827-2837 ◽  
Author(s):  
Kelly M. Hines ◽  
Billy R. Ballard ◽  
Dana R. Marshall ◽  
John A. McLean
Keyword(s):  
Mass Spectrometry ◽  
Breast Tissue ◽  
Breast Diseases ◽  
Molecular Signatures ◽  
Human Breast ◽  
Human Breast Tissue ◽  
Tissue Extracts ◽  
Ms Analysis ◽  
Structural Mass Spectrometry ◽  
Structural Mass

UPLC-IM-MS/MS analysis of human breast tissue extracts distinguished cancerous and non-cancerous breast diseases by characteristic molecular signatures.

scholarly journals Structural Mass Spectrometry: Rapid Methods for Separation and Analysis of Peptide Natural Products

2012 ◽  
Vol 75 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Cody R. Goodwin ◽  
Larissa S. Fenn ◽  
Dagmara K. Derewacz ◽  
Brian O. Bachmann ◽  
John A. McLean
Keyword(s):  
Mass Spectrometry ◽  
Natural Products ◽  
Rapid Methods ◽  
Structural Mass Spectrometry ◽  
Structural Mass
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