scholarly journals Investigation of D76N β2-Microglobulin Using Protein Footprinting and Structural Mass Spectrometry

Author(s):  
Owen Cornwell ◽  
James R. Ault ◽  
Nicholas J. Bond ◽  
Sheena E. Radford ◽  
Alison E. Ashcroft
2020 ◽  
Vol 221 ◽  
pp. 103761
Author(s):  
Viviane A. Bastos ◽  
Francisco Gomes-Neto ◽  
Surza Lucia G. Rocha ◽  
André Teixeira-Ferreira ◽  
Jonas Perales ◽  
...  

The Analyst ◽  
2018 ◽  
Vol 143 (11) ◽  
pp. 2459-2468 ◽  
Author(s):  
Yuwei Tian ◽  
Brandon T. Ruotolo

The comprehensive structural characterization of therapeutic antibodies is of critical importance for the successful discovery and development of such biopharmaceuticals, yet poses many challenges to modern measurement science. Here, we review the current state-of-the-art mass spectrometry technologies focusing on the characterization of antibody-based therapeutics.


2014 ◽  
Vol 10 (11) ◽  
pp. 2827-2837 ◽  
Author(s):  
Kelly M. Hines ◽  
Billy R. Ballard ◽  
Dana R. Marshall ◽  
John A. McLean

UPLC-IM-MS/MS analysis of human breast tissue extracts distinguished cancerous and non-cancerous breast diseases by characteristic molecular signatures.


2012 ◽  
Vol 75 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Cody R. Goodwin ◽  
Larissa S. Fenn ◽  
Dagmara K. Derewacz ◽  
Brian O. Bachmann ◽  
John A. McLean

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