Electrokinetic Fluid Control in Two-Dimensional Planar Microfluidic Devices

2007 ◽  
Vol 79 (19) ◽  
pp. 7485-7491 ◽  
Author(s):  
Margaret A. Lerch ◽  
Stephen C. Jacobson
Keyword(s):  
Microfluidic Devices ◽  
Two Dimensional ◽  
Fluid Control

scholarly journals Microfabrication with Very Low-Average Power of Green Light to Produce PDMS Microchips

Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 607
Author(s):  
Lucero M. Hernandez-Cedillo ◽  
Francisco G. Vázquez-Cuevas ◽  
Rafael Quintero-Torres ◽  
Jose L. Aragón ◽  
Miguel Angel Ocampo Mortera ◽  
...  
Keyword(s):  
Low Cost ◽  
Average Power ◽  
Green Light ◽  
Microfluidic Devices ◽  
Processing Parameters ◽  
Coating Film ◽  
Two Dimensional ◽  
Dimethyl Siloxane ◽  
Visible Laser ◽  
High Absorption

In this article, we show an alternative low-cost fabrication method to obtain poly(dimethyl siloxane) (PDMS) microfluidic devices. The proposed method allows the inscription of micron resolution channels on polystyrene (PS) surfaces, used as a mold for the wanted microchip’s production, by applying a high absorption coating film on the PS surface to ablate it with a focused low-power visible laser. The method allows for obtaining micro-resolution channels at powers between 2 and 10 mW and can realize any two-dimensional polymeric devices. The effect of the main processing parameters on the channel’s geometry is presented.

scholarly journals Wax-Printed Fluidic Time Delays for Automating Multi-Step Assays in Paper-Based Microfluidic Devices (MicroPADs)

Inventions ◽  
2019 ◽  
Vol 4 (1) ◽  
pp. 20 ◽  
Author(s):  
E. Strong ◽  
Carsten Knutsen ◽  
Jay Wells ◽  
Aditya Jangid ◽  
Megan Mitchell ◽  
...  
Keyword(s):  
Time Delays ◽  
Point Of Care ◽  
Microfluidic Devices ◽  
Fabrication Technique ◽  
Enzymatic Assays ◽  
Real World Applications ◽  
Test Zone ◽  
Fluid Control ◽  
Long Channel ◽  
Ideal Method

Microfluidic paper-based analytical devices (microPADs) have emerged as a promising platform for point-of-care diagnostic devices. While the inherent wicking properties of microPADs allow for fluid flow without supporting equipment, this also presents a major challenge in achieving robust fluid control, which becomes especially important when performing complex multi-step assays. Herein, we describe an ideal method of fluid control mediated by wax-printed fluidic time delays. This method relies on a simple fabrication technique, does not utilize chemicals/reagents that could affect downstream assays, is readily scalable, and has a wide temporal range of tunable fluid control. The delays are wax printed on both the top and bottom of pre-fabricated microPAD channels, without subsequent heating, to create hemi-/fully-enclosed channels. With these wax printed delays, we were able to tune the time it took aqueous solutions to wick across a 25 mm-long channel between 3.6 min and 13.4 min. We then employed these fluid delays in the sequential delivery of four dyes to a test zone. Additionally, we demonstrated the automation of two simple enzymatic assays with this fluid control modality. This method of fluid control may allow future researchers to automate more complex assays, thereby further advancing microPADs toward real-world applications.

High-Efficiency, Two-Dimensional Separations of Protein Digests on Microfluidic Devices

2003 ◽  
Vol 75 (15) ◽  
pp. 3758-3764 ◽  
Author(s):  
Jeremy D. Ramsey ◽  
Stephen C. Jacobson ◽  
Christopher T. Culbertson ◽  
J. Michael Ramsey
Keyword(s):  
High Efficiency ◽  
Microfluidic Devices ◽  
Two Dimensional ◽  
Protein Digests

scholarly journals Optothermal grid activation of microflow with magnetic nanoparticle thermophoresis for microfluidics

2022 ◽  
Vol 380 (2217) ◽  
Author(s):  
D. Y. Zablotsky ◽  
A. Mezulis ◽  
E. Blums ◽  
M. M. Maiorov
Keyword(s):  
Magnetic Nanoparticle ◽  
Microfluidic Devices ◽  
The Other ◽  
Two Dimensional ◽  
Theme Issue ◽  
All Optical ◽  
Magnetic Nanofluids ◽  
Optical Mixing ◽  
Magnetomechanical Coupling ◽  
The Magnetic Field

We report focused light-induced activation of intense magnetic microconvection mediated by suspended magnetic nanoparticles in microscale two-dimensional optothermal grids. Fully anisotropic control of microflow and mass transport fluxes is achieved by engaging the magnetic field along one or the other preferred directions. The effect is based on the recently described thermal diffusion–magnetomechanical coupling in synthetic magnetic nanofluids. We expect that the new phenomenon can be applied as an efficient all-optical mixing strategy in integrated microfluidic devices. This article is part of the theme issue ‘Transport phenomena in complex systems (part 2)’.

High Performance Two Dimensional Separations of Tryptic Digests on Microfluidic Devices

2002 ◽  
pp. 608-610 ◽  
Author(s):  
Stephen C. Jacobson ◽  
Jeremy D. Ramsey ◽  
Christopher T. Culbertson ◽  
J. Michael Ramsey
Keyword(s):  
High Performance ◽  
Microfluidic Devices ◽  
Two Dimensional

scholarly journals Integrated wax valve for robust fluid control in an electrochemical fabric-based device

2019 ◽  
Vol 11 (40) ◽  
pp. 5098-5107 ◽  
Author(s):  
Corey Downs ◽  
Arianna Nejely ◽  
Elain Fu
Keyword(s):  
Microfluidic Devices ◽  
Novel Approach ◽  
Fluid Control

We present a wax-based valve as a novel approach for fluid control in fabric-based microfluidic devices.

Influence of channel position on sample confinement in two-dimensional planar microfluidic devices

Lab on a Chip ◽  
2008 ◽  
Vol 8 (2) ◽  
pp. 316-322 ◽  
Author(s):  
Margaret A. Lerch ◽  
Michelle D. Hoffman ◽  
Stephen C. Jacobson
Keyword(s):  
Microfluidic Devices ◽  
Two Dimensional

Two-dimensional protein separation in microfluidic devices

2009 ◽  
Vol 30 (5) ◽  
pp. 758-765 ◽  
Author(s):  
Hong Chen ◽  
Z. Hugh Fan
Keyword(s):  
Protein Separation ◽  
Microfluidic Devices ◽  
Two Dimensional
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