Single fiber-optic fluorescence enzyme-based sensor

1988 ◽  
Vol 60 (5) ◽  
pp. 433-435 ◽  
Author(s):  
Ming Ren S. Fuh ◽  
Lloyd W. Burgess ◽  
Gary D. Christian
Keyword(s):  
Sensors ◽  
2020 ◽  
Vol 20 (9) ◽  
pp. 2595 ◽  
Author(s):  
Daniele Tosi ◽  
Carlo Molardi ◽  
Wilfried Blanc ◽  
Tiago Paixão ◽  
Paulo Antunes ◽  
...  

Optical backscatter reflectometry (OBR) is a method for the interrogation of Rayleigh scattering occurring in each section of an optical fiber, resulting in a single-fiber-distributed sensor with sub-millimeter spatial resolution. The use of high-scattering fibers, doped with MgO-based nanoparticles in the core section, provides a scattering increase which can overcome 40 dB. Using a configuration-labeled Scattering-Level Multiplexing (SLMux), we can arrange a network of high-scattering fibers to perform a simultaneous scan of multiple fiber sections, therefore extending the OBR method from a single fiber to multiple fibers. In this work, we analyze the performance and boundary limits of SLMux, drawing the limits of detection of N-channel SLMux, and evaluating the performance of scattering-enhancement methods in optical fibers.


2020 ◽  
Vol 129 ◽  
pp. 106060 ◽  
Author(s):  
Pengfei Ma ◽  
Kun Liu ◽  
Zhenshi Sun ◽  
Junfeng Jiang ◽  
Shuang Wang ◽  
...  

Optik ◽  
2020 ◽  
Vol 203 ◽  
pp. 163971 ◽  
Author(s):  
Lu Wang ◽  
Yu Wang ◽  
Yaqi Deng ◽  
Aboelmagd Noureldin ◽  
Pingfei Li

1995 ◽  
Vol 49 (4) ◽  
pp. 486-492 ◽  
Author(s):  
Andrew Fong ◽  
Gary M. Hieftje

A simple, inexpensive near-IR spectrophotometer is described that employs single fiber-optic strands in a diffuse-transmission geometry. The instrument can examine unusually small sample volumes and offers sufficient throughput to perform multicomponent analyses on diffusely transmitting powdered samples. Control of the effective optical pathlength is found to be critical in obtaining reproducible results when scattering samples are to be analyzed. A pseudo-double-beam arrangement is employed to reduce instrument noise and to set the optical pathlength independently for each sample. Sample sizes of only a few tens of milligrams are required for analysis. The resulting performance is nearly equivalent to that of a commercial reflectance instrument. An average standard error of prediction of 2.77% w/w was obtained for four-component mixtures of benzoic acid derivatives. The single-fiber transmission geometry is shown to be useful also in the near-IR analysis of microliter volumes of liquids. A standard error of cross-validation of 17 mM sodium chloride dissolved in water was achieved.


1996 ◽  
Vol 50 (3) ◽  
pp. 382-387 ◽  
Author(s):  
Jeffrey F. Aust ◽  
Karl S. Booksh ◽  
Michael L. Myrick

A novel probe design for in situ fiber-optic Raman spectroscopy has been tested and employed for real-time monitoring of an epoxy curing. The epoxy system consists of diglycidylether of bisphenol-A and polyoxypropylenetriamine. The probe consists of a single fiber optic and a small section of Teflon® tubing. The tube acts as a waveguide and sample holder. Raman signal enhancements of 15 x were observed with the employment of the tube compared to those of spectra acquired with the single fiber alone. This analysis studied the C-H stretching region of the epoxide, where previously studies have centered around the fingerprint region. The small volume of the probe and large surface area allow it to be used effectively as a method of polymer thin-film measurement. It is also effective in bulk polymer measurements because of a negligible amount of heat trapped in the sample during curing. This gives the probe a temperature and reaction rate characteristic of the polymer surrounding it. Multivariate analysis was employed to interpret and analyze the numerous spectra taken during analyses. Multivariate techniques show that both curing and sample internal temperature information can be derived from the Raman spectra.


1993 ◽  
Vol 93 (4) ◽  
pp. 2323-2323
Author(s):  
Frank W. Cuomo ◽  
Trung D. Nguyen ◽  
Allan J. Zuckerwar

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