scholarly journals Facing the SARS-CoV-2 Outbreak: What Should Obstetricians and Gynecologists Do?

2020 ◽  
Vol 14 (4) ◽  
pp. e19-e21
Author(s):  
Hongyuan Zhang ◽  
Yuanjing Hu ◽  
Yingjun Zhu ◽  
Xu Chen
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
North China ◽  
Treatment Process ◽  
Diagnosis And Treatment ◽  
Obstetrics And Gynecology ◽  
Special Group ◽  
Key Points ◽  
Major Outbreak ◽  
Available Information

ABSTRACTAn outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. In this major outbreak, women are a special group, especially pregnant patients. Many problems faced by clinicians are still unclear and need to be solved. As the largest obstetrics and gynecology hospital in North China, here we summarize the diagnosis and treatment process and key points of obstetrics and gynecology patients in our hospital during the period of the COVID-19 pandemic, hoping to provide available information to inform care of obstetrics and gynecology patients.

scholarly journals Carcinoembryonic Antigen Elevation in a Patient with SARS-CoV-2 and a History of Colon Cancer

2021 ◽  
pp. 802-805
Author(s):  
Taha Alrifai ◽  
Anita Sharko ◽  
William T. Leslie
Keyword(s):  
Health Care ◽  
Colon Cancer ◽  
Severe Acute Respiratory Syndrome ◽  
Carcinoembryonic Antigen ◽  
Health Care Delivery ◽  
Care Delivery ◽  
Prognostic Biomarkers ◽  
Diagnosis And Treatment ◽  
Routine Surveillance ◽  
History Of

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic continues to affect millions of people and impact health-care delivery worldwide. New data and insights into the diagnosis and treatment of SARS-CoV-2 are emerging rapidly. Several prognostic biomarkers have been studied in patients with SARS-CoV-2. Among those biomarkers is the carcinoembryonic antigen (CEA). We report the case of a 46-year-old male with a history of colon cancer who was found to have an elevated CEA level during routine surveillance. Further workup confirmed a diagnosis of SARS-CoV-2 infection. The CEA level normalized with the resolution of the infection.

Síndrome Respiratória Aguda Grave e a COVID-19 (SARS-Cov-2): uma revisão narrativa

2020 ◽  
Vol 11 (2.ESP) ◽  
Author(s):  
Maria Soraya Pereira Franco Adriano ◽  
Betânia Maria Pereira Santos ◽  
Carmem Gabriela Gomes de Figueiredo Figueiredo ◽  
Ana Carolina Bernardes Dulgheroff ◽  
Ronaldo Rodrigues Sarmento ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Health Professionals ◽  
Scientific Community ◽  
Scientific Production ◽  
Diagnosis And Treatment ◽  
Effective Vaccine ◽  
Disease Clinic ◽  
The World ◽  
Different Parts ◽  
Coronavirus Infections

Objetivo: Analisar a produção científica acerca da atual pandemia do novo coronavírus, destacando aspectos referentes às características do vírus, bem como a epidemiologia, o diagnóstico e tratamento da COVID-19 no intuito de fornecer informações aos profissionais de saúde e à comunidade científica. Método: Revisão narrativa, com busca nas bases de dados Scielo, Medline, Lilacs e Pubmed, referente ao período de fevereiro a maio de 2020, utilizando os descritores: “infecções por coronavírus” or “coronavirus infections”, “COVID-19”, “betacoronavirus”, “Síndrome Respiratória Aguda Grave”, “SARS-Cov-2”, “diagnóstico”, “diagnosis”. Resultados: Foram evidenciadas três categorias temáticas: aspectos referentes ao vírus; a epidemiologia e a clínica da doença; e aspectos do diagnóstico e tratamento. Conclusão: O Coronavírus sofreu mutações desde o início da pandemia, mas não se sabe se estas mutações afetaram seu poder de infecciosidade. Em diferentes partes do mundo a epidemiologia da COVID-19 foi diferente. Com relação ao tratamento, a droga que tem se mostrado mais promissora até o momento é o remdesivir. Sem uma vacina eficaz, a maior arma que dispomos é o isolamento social.Descritores: Infecções por Coronavírus; COVID-19; Síndrome Respiratória Aguda Grave. SEVERE ACUTE RESPIRATORY SYNDROME AND COVID-19 (SARS-COV-2): A NARRATIVE REVIEWObjective: To analyze a scientific production on the current pandemic of new coronaviruses, highlighting aspects related to virus resources, as well as the epidemiology, diagnosis and treatment of COVID-19 in order to provide information to health professionals and the scientific community. Method: Narrative review, searching the Scielo, Medline, Lilacs and Pubmed databases, for the period from February to May 2020, using the keywords: "coronavirus infections" or "coronavirus infections", "COVID-19", "Betacoronavirus", "Severe Acute Respiratory Syndrome", "SARS-Cov-2", "diagnosis", "diagnosis". Results: Three thematic categories were highlighted: aspects related to the virus; an epidemiology and disease clinic; and aspects of diagnosis and treatment. Conclusion: The Coronavirus has mutated since the beginning of the pandemic, but it is not known whether these mutations have affected its infectiousness. In different parts of the world the epidemiology of COVID-19 was different. Regarding treatment, a drug that has been shown to be more promising until recovery is needed. Without an effective vaccine, the biggest weapon that affects social isolation.Descriptors: Coronavirus Infections; COVID-19; Severe Acute Respiratory Syndrome. SÍNDROME RESPIRATORIO AGUDO GRAVE Y COVID-19 (SARS-COV-2): UNA REVISIÓN NARRATIVAObjetivo: analizar una producción científica sobre la pandemia actual de nuevos coronavirus, destacando aspectos relacionados con los recursos del virus, así como la epidemiología, diagnóstico y tratamiento de COVID-19 para proporcionar información a los profesionales de la salud y la comunidad científica. Método: Revisión narrativa, buscando en las bases de datos Scielo, Medline, Lilacs y Pubmed, para el período de febrero a mayo de 2020, utilizando los descriptores: "infecciones por coronavirus" o "infecciones por coronavirus", "COVID-19", "Betacoronavirus", "Síndrome respiratorio agudo severo", "SARS-Cov-2", "diagnóstico", "diagnóstico". Resultados: se destacaron tres categorías temáticas: aspectos relacionados con el virus; una clínica de epidemiología y enfermedad; y aspectos de diagnóstico y tratamiento. Conclusión: el coronavirus ha mutado desde el comienzo de la pandemia, pero no se sabe si estas mutaciones han afectado su infecciosidad. En diferentes partes del mundo, la epidemiología de COVID-19 fue diferente. Con respecto al tratamiento, un medicamento que ha demostrado ser más prometedor hasta que se necesita recuperación. Sin una vacuna efectiva, el arma más grande que afecta el aislamiento social.Descriptores: Infecciones por Coronavirus; COVID-19; Síndrome Respiratorio Agudo Severo.

scholarly journals Updated S3 Guidelines – Diagnosis and Treatment of Colorectal Carcinoma: Relevance for Radiological Diagnosis and Intervention

2018 ◽  
Vol 191 (04) ◽  
pp. 298-310 ◽  
Author(s):  
Thomas Vogl ◽  
Philippe Pereira ◽  
Thomas Helmberger ◽  
Andreas Schreyer ◽  
Wolff Schmiegel ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Metabolic Disorders ◽  
German Society ◽  
Radiological Diagnosis ◽  
Diagnosis And Treatment ◽  
Cancer Society ◽  
S3 Guidelines ◽  
Key Points ◽  
Palliative Situation

The updated German S3 guidelines “Colorectal Carcinoma“ were created as part of the oncology program of the Association of the Scientific Medical Societies (AWMF), German Cancer Society and the German Cancer Aid under the auspices of the German Society for Digestive and Metabolic Disorders (DGVS) and they replace the previous guidelines from 2013. The main changes in the updated guidelines include the latest recommendations regarding endoscopy and adjuvant/neoadjuvant therapies as well as a complete restructuring of the section regarding therapeutic approach in metastases and in the palliative situation. The present manuscript discusses the importance of the current recommendations for radiological diagnosis and treatment and is intended to enhance the quality of patient information and patient care by widespread distribution. Key Points:  Citation Format

scholarly journals Current Drugs with Potential for Treatment of COVID-19: A Literature Review

2020 ◽  
Vol 23 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Md Insiat Islam Rabby
Keyword(s):  
Clinical Trial ◽  
Severe Acute Respiratory Syndrome ◽  
Laboratory Tests ◽  
Literature Search ◽  
Treatment Process ◽  
Clinical Use ◽  
Animal Trial ◽  
Chinese Drugs ◽  
Inflammatory Drugs ◽  
Traditional Chinese Drugs

Purpose: SARS-CoV-2 first emerged in China in December 2019 and rapidly spread worldwide. No vaccine or approved drug is available to eradicate the virus, however, some drugs that are indicated for other afflictions seems to be potentially beneficial to treat the infection albeit without unequivocal evidence.   The aim of this article is to review the published background on the effectiveness of these drugs against COVID-19 Methods: A thorough literature search was conducted on recently published studies which have published between January 1 to March 25, 2020. PubMed, Google Scholar and Science Direct databases were searched Results: A total 22 articles were found eligible. 8 discuss about treatment outcomes from their applied drugs during treatment of COVID-19 patients, 4 report laboratory tests, one report animal trial and other 9 articles discuss recommendations and suggestions based on the treatment process and clinical outcomes of other diseases such as malaria, ebola, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). The data and/or recommendations are categorized in 4 classes: (a) anti-viral and anti-inflammatory drugs, (b) anti-malaria drugs, (c) traditional Chinese drugs and (d) other treatments/drugs. Conclusion: All examined treatments, although potentiality effective against COVID-19, need either appropriate drug development or clinical trial to be suitable for clinical use.

scholarly journals Intracranial Subdural Hematoma after Spinal Anesthesia: Report of Two Cases with different Outcomes

2019 ◽  
Vol 38 (03) ◽  
pp. 215-218
Author(s):  
Guilherme Gago ◽  
Otávio Garcia Martins ◽  
Pedro Luís Gobatto ◽  
Fernando Antônio de Oliveira Costa ◽  
Ricardo Santin ◽  
...  
Keyword(s):  
Spinal Anesthesia ◽  
Present Article ◽  
Local Anesthesia ◽  
Subdural Hematoma ◽  
Diagnosis And Treatment ◽  
Neurological Deficits ◽  
Diagnosis And Management ◽  
Key Points

AbstractSpinal anesthesia is a technique commonly used for local anesthesia and in obstetric surgeries. Rarely, the formation of an intracranial subdural hematoma (SDH) may result from spinal anesthesia, constituting a serious condition that often leads to severe neurological deficits. The presentation and course of this pathology may occur in a completely different way, which makes its diagnosis and management difficult. In the present article, the authors report two cases of patients with intracranial SDH after spinal anesthesia with completely different presentations and outcomes, demonstrating the variability of the manifestations of this condition. A quick review of key points of its pathophysiology, symptomatology, diagnosis, and treatment was also performed.

Medical IT Systems and Their Effect on Human Resources

2009 ◽  
pp. 649-654
Author(s):  
Robert J. Mockler ◽  
Dorothy G. Dologite
Keyword(s):  
Human Resources ◽  
Treatment Process ◽  
Information Source ◽  
Healthcare Services ◽  
The Other ◽  
Accurate Information ◽  
Services Delivery ◽  
It Systems ◽  
Appropriate Treatment ◽  
Available Information

Initially, substantial information regarding the patient’s condition upon entrance into the hospital or emergency room is needed and has to be recorded in a readily available information source. To be effective, then, accurate information on the patient’s prior treatment and conditions is needed promptly and completely at each phase of the treatment process by the appropriate professional healthcare provider. Subsequently, the professionals treating the patient need to record information at each point in the treatment process in order for each professional to be able to effectively identify the nature of the ailment and to recommend and then perform the appropriate treatment. Problems arise with this process when it is largely paper-based or stored in nonintegrated systems. Medical IT systems, on the other hand, can affect improvement of healthcare services delivery at hospitals, as this chapter will show.

Comprehensive analysis of SARS-COV-2 drug targets and pharmacological aspects in treating the COVID-19

2021 ◽  
Vol 14 ◽  
Author(s):  
Sundaresan Bhavaniramya ◽  
Vanajothi Ramar ◽  
Selvaraju Vishnupriya ◽  
Ramasamy Palaniappan ◽  
Ashokkumar Sibiya ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Global Economy ◽  
Drug Targets ◽  
Respiratory Diseases ◽  
The Novel ◽  
Virus Diseases ◽  
Current Review ◽  
Major Outbreak ◽  
Corona Viruses ◽  
Viral Outbreak

: Corona viruses are enveloped, single-stranded RNA (Ribonucleic acid) viruses and they cause pandemic diseases having a devastating effect on both human healthcare and the global economy. To date, six corona viruses have been identified as pathogenic organisms which are significantly responsible for the infection and also cause severe respiratory diseases. Among them, the novel SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) caused a major outbreak of corona virus diseases 2019 (COVID-19). Coronaviridae family members can affects both humans and animals. In human, corona viruses cause severe acute respiratory syndrome with mild to severe outcomes. Several structural and genomics have been investigated, and the genome encodes about 28 proteins most of them with unknown function though it shares remarkable sequence identity with other proteins. There is no potent and licensed vaccine against SARS-CoV-2 and several trials are underway to investigate the possible therapeutic agents against viral infection. However, some of the antiviral drugs that have been investigated against SARS-CoV-2 are under clinical trials. In the current review we comparatively emphasize the emergence and pathogenicity of the SARS-CoV-2 and their infection and discuss the various putative drug targets of both viral and host receptors for developing effective vaccines and therapeutic combinations to overcome the viral outbreak.

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