scholarly journals Satellite-cell pool size does matter: Defining the myogenic potency of aging skeletal muscle

2006 ◽  
Vol 294 (1) ◽  
pp. 50-66 ◽  
Author(s):  
Gabi Shefer ◽  
Daniel P. Van de Mark ◽  
Joshua B. Richardson ◽  
Zipora Yablonka-Reuveni
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Pool Size ◽  
Cell Pool

scholarly journals Satellite cell pool size expansion is affected by skeletal muscle characteristics

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Filippo Macaluso ◽  
Naomi E Brooks ◽  
Carola U Niesler ◽  
Kathy H Myburgh
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Pool Size ◽  
Cell Pool

scholarly journals Influence of sex and fiber type on the satellite cell pool in human skeletal muscle

2020 ◽  
Author(s):  
Oscar Horwath ◽  
Marcus Moberg ◽  
Filip J. Larsen ◽  
Andrew Philp ◽  
William Apró ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Human Skeletal Muscle ◽  
Fiber Type ◽  
Cell Pool

scholarly journals Muscle satellite cells adopt divergent fates

2004 ◽  
Vol 166 (3) ◽  
pp. 347-357 ◽  
Author(s):  
Peter S. Zammit ◽  
Jon P. Golding ◽  
Yosuke Nagata ◽  
Valérie Hudon ◽  
Terence A. Partridge ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Satellite Cells ◽  
Muscle Regeneration ◽  
Cell Phenotype ◽  
Proliferating Cells ◽  
Cell Compartment ◽  
Adult Skeletal Muscle ◽  
Muscle Stem Cells ◽  
Cell Pool

Growth, repair, and regeneration of adult skeletal muscle depends on the persistence of satellite cells: muscle stem cells resident beneath the basal lamina that surrounds each myofiber. However, how the satellite cell compartment is maintained is unclear. Here, we use cultured myofibers to model muscle regeneration and show that satellite cells adopt divergent fates. Quiescent satellite cells are synchronously activated to coexpress the transcription factors Pax7 and MyoD. Most then proliferate, down-regulate Pax7, and differentiate. In contrast, other proliferating cells maintain Pax7 but lose MyoD and withdraw from immediate differentiation. These cells are typically located in clusters, together with Pax7−ve progeny destined for differentiation. Some of the Pax7+ve/MyoD−ve cells then leave the cell cycle, thus regaining the quiescent satellite cell phenotype. Significantly, noncycling cells contained within a cluster can be stimulated to proliferate again. These observations suggest that satellite cells either differentiate or switch from terminal myogenesis to maintain the satellite cell pool.

Elevated p21 mRNA level in skeletal muscle of DMD patients and mdx mice indicates either an exhausted satellite cell pool or a higher p21 expression in dystrophin-deficient cells per se

2000 ◽  
Vol 78 (10) ◽  
pp. 569-574 ◽  
Author(s):  
Stefanie Endesfelder ◽  
Antje Krahn ◽  
Karl-Anton Kreuzer ◽  
Ulrich Lass ◽  
Christian Andreas Schmidt ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Mrna Level ◽  
Mdx Mice ◽  
Cell Pool ◽  
Per Se

Satellite cell pool expansion is affected by skeletal muscle characteristics

2013 ◽  
Vol 48 (1) ◽  
pp. 109-116 ◽  
Author(s):  
Filippo Macaluso ◽  
Naomi E. Brooks ◽  
Carola U. Niesler ◽  
Kathryn H. Myburgh
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Cell Pool

scholarly journals Angiotensin II depletes the skeletal muscle satellite cell pool and prevents skeletal muscle regeneration

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Tadashi Yoshida ◽  
Sarah Galvez ◽  
Bashir M. Rezk ◽  
Laura Semprun-Prieto ◽  
Sergiy Sukhanov ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Angiotensin Ii ◽  
Satellite Cell ◽  
Muscle Regeneration ◽  
Skeletal Muscle Regeneration ◽  
Muscle Satellite Cell ◽  
Cell Pool ◽  
Skeletal Muscle Satellite Cell
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