Confinement of Amorphous Lactose in Pores Formed Upon Co-Spray Drying With Nanoparticles

Joel Hellrup; Denny Mahlin

doi:10.1016/j.xphs.2016.09.032

Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

Journal of Pharmaceutical Sciences ◽

10.1002/jps.24583 ◽

2015 ◽

Vol 104 (11) ◽

pp. 3760-3769 ◽

Cited By ~ 9

Author(s):

Joel Hellrup ◽

Göran Alderborn ◽

Denny Mahlin

Keyword(s):

Spray Drying ◽

Amorphous Lactose

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Temperature- and Moisture-Induced Crystallization of Amorphous Lactose in Composite Particles with Sodium Alginate Prepared by Spray-Drying

Pharmaceutical Development and Technology ◽

10.1081/pdt-100100551 ◽

2000 ◽

Vol 5 (3) ◽

pp. 355-363 ◽

Cited By ~ 16

Author(s):

Hirofumi Takeuchi ◽

Takehiko Yasuji ◽

Hiromitsu Yamamoto ◽

Yoshiaki Kawashima

Keyword(s):

Sodium Alginate ◽

Spray Drying ◽

Composite Particles ◽

Amorphous Lactose ◽

Induced Crystallization

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Preparation and Characterization of Monodispersed and Spherical YAG Powder for Transparent Ceramic by Spray Drying

Journal of Inorganic Materials ◽

10.15541/jim20140533 ◽

2015 ◽

Vol 30 (5) ◽

pp. 487 ◽

Cited By ~ 1

Author(s):

ZHANG Le ◽

ZHOU Tian-Yuan ◽

YANG Hao ◽

QIAO Xue-Bin ◽

WANG Zhong-Ying ◽

...

Keyword(s):

Spray Drying ◽

Transparent Ceramic

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OSA modified starch in lipid encapsulation by spray drying

Engineering Sciences And Technologies ◽

10.15611/nit.2013.3.04 ◽

2013 ◽

pp. 45-61

Author(s):

Ewa Domian ◽

Ewa Świrydow ◽

Jan Cenkier

Keyword(s):

Spray Drying ◽

Modified Starch

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Optimization of Microcrystalline Cellulose PH 101, Lactose, and Kollidon® K 30 To Obtain Co-Processed Excipient Through Spray Drying

International Journal of Drug Delivery Technology ◽

10.25258/ijddt.v7i2.8921 ◽

2017 ◽

Vol 7 (2) ◽

Author(s):

Kusuma P. ◽

Syukri Y ◽

Sholehuddin F. ◽

Fazzri N. ◽

Romdhonah . ◽

...

Keyword(s):

Spray Drying ◽

Microcrystalline Cellulose ◽

Chemical Change ◽

Direct Compression ◽

Flow Properties ◽

Scanning Calorimetry ◽

Compression Process ◽

Infrared Spectrophotometer ◽

Physical Mixtures ◽

Spray Dried

The most efficient tablet processing method is direct compression. For this method, the filler-binder can be made by coprocessing via spray drying method. The purpose of this study was to investigate the effect of spray dried co-processing on microcrystalline cellulose (MCC) PH 101, lactose and Kollidon® K 30 as well as to define the optimum proportions. Spray dried MCC PH 101, lactose, and Kollidon® K 30 were varied in 13 different mixture design proportions to obtain compact, free-flowing filler-binder co-processed excipients (CPE). Compactibility and flow properties became the key parameters to determine the optimum proportions of CPE that would be compared to their physical mixtures. The result showed that the optimum proportion of CPE had better compactibility and flow properties than the physical mixtures. The optimum CPE, consisting of only MCC PH 101 and Kollidon® K 30 without lactose, that were characterized using infrared spectrophotometer, differential scanning calorimetry (DSC), X-ray diffraction (XRD), and scanning electron microscope (SEM) indicated no chemical change therein. Therefore, this study showed that spray dried MCC PH 101, lactose and Kollidon® K 30 could be one of the filler-binder alternatives for direct compression process.

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Spray Drying as a Method for Formation of Co-amorphous Drug-Amino-Acid Mixtures

10.26226/morressier.57d6b2b6d462b8028d88d7be ◽

2016 ◽

Author(s):

Jaya Mishra

Keyword(s):

Amino Acid ◽

Spray Drying ◽

Amino Acid Mixtures ◽

Amorphous Drug

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Solid Dispersions with Anionic EUDRAGIT&[reg] Polymers Using Spray Drying Technique to Increase the Solubility of Poorly Soluble Drugs

10.26226/morressier.57d6b2bdd462b8028d88d414 ◽

2016 ◽

Author(s):

Jitendra Amrutkar

Keyword(s):

Spray Drying ◽

Solid Dispersions ◽

Poorly Soluble Drugs ◽

Poorly Soluble

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TEKNOLOGI PENANGANAN EMISI GAS DARI INSINERATOR SAMPAH KOTA

Jurnal Rekayasa Lingkungan ◽

10.29122/jrl.v11i2.3465 ◽

2019 ◽

Vol 11 (2) ◽

Author(s):

Prasetiyadi Prasetiyadi ◽

Wiharja Wiharja ◽

Sri Wahyono

Keyword(s):

Fly Ash ◽

Pressure Drop ◽

Spray Drying ◽

Flue Gas ◽

Bag Filter

Proses pembakaran sampah kota melalui insinerator akan menghasilkan uap panas yang bisa dimanfaatkan untuk membangkitkan energi listrik, akan tetapi pada proses ini juga menghasilkan output berupa flue gas yang didominasi oleh partikel (fly ash) dan gas beracun seperti: HCl, SO2, NOx, HF, Hg, Cd dan Dioxin. Sebelum dibuang ke udara bebas, flue gas tersebut harus diolah agar memenuhi baku mutu lingkungan. Teknologi penanganan partikel dan gas polutan tersedia dan dapat dibuat dengan berbagai kapasitas. Untuk menangani flue gas dari insinerator sampah digunakan Quencher untuk menekan laju pembentukan kembali dioksin dan furan setelah proses pembakaran, Spray Drying Absorption (SDA) untuk mengikat gas asam dan logam berat serta bag filter untuk menangkap partikel. Selain itu digunakan ID Fan dan Cerobong Asap untuk pengatasi pressure drop yang terjadi akibat pengoperasian peralatan APC dan melepas ke udara.

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