Microwave-assisted RAFT polymerization of N-(2-hydroxypropyl) methacrylamide and its relevant copolymers

2021 ◽  
Vol 162 ◽  
pp. 104875
Author(s):  
Vladimir Sincari ◽  
Svetlana Lukáš Petrova ◽  
Rafał Konefał ◽  
Martin Hruby ◽  
Eliézer Jäger
Keyword(s):  
Raft Polymerization ◽  
Microwave Assisted ◽  
Hydroxypropyl Methacrylamide

Poly[N-(2-hydroxypropyl)methacrylamide] nanogels by RAFT polymerization in inverse emulsion

2014 ◽  
Vol 5 (5) ◽  
pp. 1711-1719 ◽  
Author(s):  
Harald Wutzel ◽  
Felix H. Richter ◽  
Yuanchao Li ◽  
Sergei S. Sheiko ◽  
Harm-Anton Klok
Keyword(s):  
Raft Polymerization ◽  
Inverse Emulsion ◽  
Hydroxypropyl Methacrylamide

Synthesis of siRNA Polyplexes Adopting a Combination of RAFT Polymerization and Thiol-ene Chemistry

2009 ◽  
Vol 62 (10) ◽  
pp. 1344 ◽  
Author(s):  
David Valade ◽  
Cyrille Boyer ◽  
Thomas P. Davis ◽  
Volga Bulmus
Keyword(s):  
Block Copolymers ◽  
High Efficiency ◽  
Raft Polymerization ◽  
Hydrodynamic Diameter ◽  
Small Interfering Rnas ◽  
Buffer Solution ◽  
Polyelectrolyte Complexes ◽  
Reversible Addition ◽  
Hydroxypropyl Methacrylamide ◽  
Cationic Copolymers

Block copolymers of allyl methacrylate and N-(2-hydroxypropyl)methacrylamide (HPMA) with different block lengths have been synthesized by reversible addition–fragmentation chain transfer polymerization. Allyl groups were modified with cysteamine, via a thiol-ene photoreaction, with a high efficiency (~100%) as evidenced by NMR spectroscopy, yielding cationic copolymers of HPMA. Polyelectrolyte complexes of small interfering RNAs (siRNA) and the cationic block copolymers were then formed at an N/P ratio between 1 and 4 depending on the block length of the copolymers. Increasing the length of the hydrophilic block was found to decrease the efficiency of siRNA complexation. The hydrodynamic diameter of the polyplexes in 130 mM buffer solution was less than 100 nm.

Synthesis of poly(N-(2-hydroxypropyl) methacrylamide) brushes by interface-mediated RAFT polymerization

RSC Advances ◽  
2016 ◽  
Vol 6 (51) ◽  
pp. 45259-45264 ◽  
Author(s):  
Ertan Yildirim ◽  
Dilek Cimen ◽  
Adem Zengin ◽  
Tuncer Caykara
Keyword(s):  
Raft Polymerization ◽  
Polymer Brush ◽  
Moderate Density ◽  
Hydroxypropyl Methacrylamide

A novel poly(N-(2-hydroxypropyl) methacrylamide) [poly(HPMA)] brush with a moderate density polymer brush (0.52 chains per nm2) was synthesized by an interface-mediated RAFT polymerization.

Rapid Block Copolymer Synthesis by Microwave-Assisted RAFT Polymerization

2009 ◽  
Vol 42 (20) ◽  
pp. 7701-7708 ◽  
Author(s):  
Debashish Roy ◽  
Aman Ullah ◽  
Brent S. Sumerlin
Keyword(s):  
Block Copolymer ◽  
Raft Polymerization ◽  
Microwave Assisted

Microwave-assisted rapid one-step synthesis of poly(2-oxazoline)-based block copolymers using a dual initiator for CROP and RAFT polymerization

Polymer ◽  
2016 ◽  
Vol 87 ◽  
pp. 108-113 ◽  
Author(s):  
Munhyung Kang ◽  
Soo Young Lee ◽  
Hwan Ho Shin ◽  
Young Chang Yu ◽  
Ji Ho Youk
Keyword(s):  
Block Copolymers ◽  
Raft Polymerization ◽  
Microwave Assisted ◽  
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