Potentiel pathogénique de Porphyromonas gingivalis, Treponema denticola et Tannerella forsythia, le complexe bactérien rouge associé à la parodontite

2007 ◽  
Vol 55 (3-4) ◽  
pp. 154-162 ◽  
Author(s):  
C. Bodet ◽  
F. Chandad ◽  
D. Grenier
Keyword(s):  
Porphyromonas Gingivalis ◽  
Treponema Denticola ◽  
Tannerella Forsythia

Presence of archaea and selected bacteria in infected root canal systems

2018 ◽  
Vol 64 (5) ◽  
pp. 317-326 ◽  
Author(s):  
Ewa Brzezińska-Błaszczyk ◽  
Elżbieta Pawłowska ◽  
Tomasz Płoszaj ◽  
Henryk Witas ◽  
Urszula Godzik ◽  
...  
Keyword(s):  
16S Rrna ◽  
16S Rrna Gene ◽  
Porphyromonas Gingivalis ◽  
Root Canal ◽  
Expression Profiles ◽  
Rna Extraction ◽  
Treponema Denticola ◽  
Rrna Gene ◽  
Pulp Tissue ◽  
Tannerella Forsythia

Infections of the root canal have polymicrobial etiology. The main group of microflora in the infected pulp is bacteria. There is limited data that archaea may be present in infected pulp tissue. The aim of this study was to check the prevalence of archaea in necrotic root canal samples obtained from patients with primary or post-treatment infection. The prevalence of selected bacteria species (Prevotella intermedia, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Synergistes sp.) in necrotic samples was evaluated as well. Sixty-four samples from root canal were collected for DNA and RNA extraction. A PCR assay based on the 16S rRNA gene was used to determine the presence of archaea and selected bacteria. Of the 64 samples, 6 were analyzed by semiquantitative reverse transcription PCR to estimate expression profiles of 16S rRNA, and another 9 were selected for direct sequencing. Archaea were detected in 48.4% samples. Statistical analysis indicated a negative association in coexistence between archaea and Treponema denticola (P < 0.05; Pearson’s χ2 test). The main representative of the Archaea domain found in infected pulp tissue was Methanobrevibacter oralis. Archaea 16S rRNA gene expression was significantly lower than Synergistes sp., Porphyromonas gingivalis, and Tannerella forsythia (P < 0.05; Student’s t test). Thus, it can be hypothesized that archaea may participate in the endodontic microbial community.

scholarly journals Mixed Red-Complex Bacterial Infection in Periodontitis

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
N. Suzuki ◽  
M. Yoneda ◽  
T. Hirofuji
Keyword(s):  
Periodontal Disease ◽  
Bacterial Infection ◽  
Porphyromonas Gingivalis ◽  
Treponema Denticola ◽  
Periodontal Tissue ◽  
Tannerella Forsythia

The red complex, which includesPorphyromonas gingivalis,Treponema denticola, andTannerella forsythia(formerlyBacteroides forsythus), are recognized as the most important pathogens in adult periodontal disease. These bacteria are usually found together in periodontal pockets, suggesting that they may cause destruction of the periodontal tissue in a cooperative manner. This article discusses the interspecies pathogenic interactions within the red complex.

scholarly journals Relative quantification of Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia and Aggregatibacter actinomycetemcomitans high-risk bacterial species in Romanian patients evaluated for periodontal disease

2017 ◽  
Author(s):  
Cosac Ion Constantin ◽  
Ionica Consuel ◽  
Ratiu Attila Cristian ◽  
Savu Lorand
Keyword(s):  
Periodontal Disease ◽  
Porphyromonas Gingivalis ◽  
Gingival Crevicular Fluid ◽  
Bacterial Species ◽  
Bacterial Load ◽  
Clinical Signs ◽  
Aggregatibacter Actinomycetemcomitans ◽  
Treponema Denticola ◽  
Tannerella Forsythia ◽  
Complex Species

AbstractThree bacterial species pertaining to the red complex (Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia) and Aggregatibacter actinomycetemcomitans were investigated in relation to the incidence and severity of periodontal disease. A total of 259 patients were included in this study, 179 being diagnosed with periodontal disease. The gingival crevicular fluid samples were obtained from periodontal pockets and the presence and levels of target bacteria were assessed following DNA extraction and real-time quantitative PCR. Our results account for significant positive associations between the number of bacterial species from the red complex coexisting within a patient and several clinical signs (gingival bleeding, inflammation and bone deterioration). A similar positive association was found between bacterial load of the red complex species and the clinical Case Type diagnostic of the periodontal disease, as well as the probing depth with the most evident results for T. denticola. In conclusion, our study, a first for the Romanian population, confirms previous results found elsewhere and finds a possible regional pathogenic specificity for T. denticola as a major factor for periodontitis severity.

scholarly journals Sistemas de administración de estatinas en el tratamiento de la periodontitis: una revisión de literatura

Ustasalud ◽  
2019 ◽  
Vol 17 ◽  
pp. 40-47
Author(s):  
Angélica María Cárdenas Gutiérrez ◽  
Alejandra Fernández ◽  
María Paulina Pieschacón ◽  
Gonzalo Navarro
Keyword(s):  
Porphyromonas Gingivalis ◽  
Treponema Denticola ◽  
Tannerella Forsythia ◽  
El Sistema

La periodontitis es la inflamación de los tejidos periodontales que puede causar destrucción de los tejidos de soporte del diente, ocasionando pérdida ósea y dental. La periodontitis crónica es causada por bacterias periodontopatógenas como Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitams, Tannerella forsythia y Treponema dentícola, que activan el sistema inmune innato y adaptativo. El tratamiento de la enfermedad periodontal involucra estrategias no quirúrgicas como el raspaje y alisado radicular y tratamiento adjunto que incluye la administración de antibióticos sistémicos y locales como metronidazol, amoxicilina, tetraciclinas, además del uso de estatinas; fármacos utilizados principalmente contra la hiperlipidemia como la simvastatina. El uso de estatinas en la enfermedad periodontal, es dado por su efecto antiinflamatorio, además de estimular la formación ósea, la angiogénesis y su actividad antimicrobiana. Para la aplicación de estos fármacos en el tratamiento de la periodontitis crónica se han utilizado diferentes medios de administración, como: geles, fibras, películas, vesículas, y nanopartículas, destacándose el gel como el sistema preferido para liberar y transportar estatinas, el cual reduce los efectos adversos de la administración sistémica y son más efectivos para la cicatrización ósea. En periodoncia, las estatinas han mostrado una disminución en los parámetros clínicos periodontales después de 6 meses de tratamiento. Sin embargo, existen pocas revisiones temáticas que permitan a la comunidad académica reunir la información pertinente al respecto. Por lo anterior, se vio la necesidad de realizar una revisión de la literatura con el fin de describir los sistemas de administración local y sistémica de estatinas en el tratamiento de la periodontitis.

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