Liver disease in cystic fibrosis

2017 ◽  
Vol 27 (12) ◽  
pp. 552-555 ◽  
Author(s):  
Indra D.M. van Mourik
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease

P069 Cystic fibrosis-related liver disease – a decade of experience

2021 ◽  
Vol 20 ◽  
pp. S59-S60
Author(s):  
A. Mocic Pavic ◽  
M. Masic ◽  
I. Trivic ◽  
S. Sila ◽  
T. Niseteo ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease ◽  
Related Liver Disease

scholarly journals Outcome in Cystic Fibrosis Liver Disease

2009 ◽  
Vol 8 ◽  
pp. S77
Author(s):  
M. Rowland ◽  
C. Gallagher ◽  
G. Canny ◽  
P. Greally ◽  
D. Slattery ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease

Emerging clinical perspectives in cystic fibrosis liver disease

2021 ◽  
Vol 27 (6) ◽  
pp. 593-599
Author(s):  
Varinder S. Athwal ◽  
Jennifer A. Scott ◽  
Emer Fitzpatrick ◽  
Marion Rowland
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease

scholarly journals Fibrosis blood tests to detect liver disease in patients with cystic fibrosis

2009 ◽  
Vol 8 ◽  
pp. S77
Author(s):  
A.C. Wagner ◽  
M. Beaumesnil ◽  
E. Chaillou ◽  
F. Troussier ◽  
E. Darviot ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease ◽  
Blood Tests

scholarly journals Cystic Fibrosis Related Liver Disease and Endocrine Considerations

2021 ◽  
pp. 100283
Author(s):  
Jordan S. Sherwood ◽  
Jagdeesh Ullal ◽  
Katherine Kutney ◽  
Kara S. Hughan
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease ◽  
Related Liver Disease

scholarly journals Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials (Preprint)

2017 ◽  
Author(s):  
Daniel Pfirrmann ◽  
Nils Haller ◽  
Yvonne Huber ◽  
Patrick Jung ◽  
Klaus Lieb ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Clinical Trials ◽  
Liver Disease ◽  
Activity Level ◽  
Daily Routine ◽  
Intervention Period ◽  
Web Based ◽  
Significant Change ◽  
Disease Specific

BACKGROUND In the primary and secondary prevention of civilization diseases, regular physical activity is recommended in international guidelines to improve disease-related symptoms, delay the progression of the disease, or to enhance postoperative outcomes. In the preoperative context, there has been a paradigm shift in favor of using preconditioning concepts before surgery. Web-based interventions seem an innovative and effective tool for delivering general information, individualized exercise recommendations, and peer support. OBJECTIVE Our first objective was to assess feasibility of our Web-based interventional concept and analyze similarities and differences in a sustained exercise implementation in different diseases. The second objective was to investigate the overall participants’ satisfaction with our Web-based concept. METHODS A total of 4 clinical trials are still being carried out, including patients with esophageal carcinoma scheduled for oncologic esophagectomy (internet-based perioperative exercise program, iPEP, study), nonalcoholic fatty liver disease (hepatic inflammation and physical performance in patients with nonalcoholic steatohepatitis, HELP, study), depression (exercise for depression, EXDEP, study), and cystic fibrosis (cystic fibrosis online mentoring for microbiome, exercise, and diet, COMMED, study). During the intervention period, the study population had access to the website with disease-specific content and a disease-specific discussion forum. All participants received weekly, individual tailored exercise recommendations from the sports therapist. The main outcome was the using behavior, which was obtained by investigating the log-in rate and duration. RESULTS A total of 20 participants (5 from each trial) were analyzed. During the intervention period, a regular contact and a consequent implementation of exercise prescription were easily achieved in all substudies. Across the 4 substudies, there was a significant decrease in log-in rates (P<.001) and log-in durations (P<.001) over time. A detailed view of the different studies shows a significant decrease in log-in rates and log-in durations in the HELP study (P=.004; P=.002) and iPEP study (P=.02; P=.001), whereas the EXDEP study (P=.58; P=.38) and COMMED study (P=.87; P=.56) showed no significant change over the 8-week intervention period. There was no significant change in physical activity within all studies (P=.31). Only in the HELP study, the physical activity level increased steadily over the period analyzed (P=.045). Overall, 17 participants (85%, 17/20) felt secure and were not scared of injury, with no major differences in the subtrials. CONCLUSIONS The universal use of the Web-based intervention appears to be applicable across the heterogonous collectives of our study patients with regard to age and disease. Although the development of physical activity shows only moderate improvements, flexible communication and tailored support could be easily integrated into patients’ daily routine. CLINICALTRIAL iPEP study: ClinicalTrials.gov NCT02478996; https://clinicaltrials.gov/ct2/show/NCT02478996 (Archived by WebCite at http://www.webcitation.org/6zL1UmHaW); HELP study: ClinicalTrials.gov NCT02526732; http://www.webcitation.org/6zJjX7d6K (Archived by WebCite at http://www.webcitation.org/6Nch4ldcL); EXDEP study: ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/6zJjj7FuA)

scholarly journals Non-invasive tools for detection of liver disease in children and adolescents with cystic fibrosis

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Antonella Tosco ◽  
Angela Sepe ◽  
Alice Castaldo ◽  
Andrea Catzola ◽  
Chiara Cimbalo ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Liver Disease ◽  
Children And Adolescents ◽  
Non Invasive
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