scholarly journals Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials (Preprint)

2017 ◽  
Author(s):  
Daniel Pfirrmann ◽  
Nils Haller ◽  
Yvonne Huber ◽  
Patrick Jung ◽  
Klaus Lieb ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Clinical Trials ◽  
Liver Disease ◽  
Activity Level ◽  
Daily Routine ◽  
Intervention Period ◽  
Web Based ◽  
Significant Change ◽  
Disease Specific

BACKGROUND In the primary and secondary prevention of civilization diseases, regular physical activity is recommended in international guidelines to improve disease-related symptoms, delay the progression of the disease, or to enhance postoperative outcomes. In the preoperative context, there has been a paradigm shift in favor of using preconditioning concepts before surgery. Web-based interventions seem an innovative and effective tool for delivering general information, individualized exercise recommendations, and peer support. OBJECTIVE Our first objective was to assess feasibility of our Web-based interventional concept and analyze similarities and differences in a sustained exercise implementation in different diseases. The second objective was to investigate the overall participants’ satisfaction with our Web-based concept. METHODS A total of 4 clinical trials are still being carried out, including patients with esophageal carcinoma scheduled for oncologic esophagectomy (internet-based perioperative exercise program, iPEP, study), nonalcoholic fatty liver disease (hepatic inflammation and physical performance in patients with nonalcoholic steatohepatitis, HELP, study), depression (exercise for depression, EXDEP, study), and cystic fibrosis (cystic fibrosis online mentoring for microbiome, exercise, and diet, COMMED, study). During the intervention period, the study population had access to the website with disease-specific content and a disease-specific discussion forum. All participants received weekly, individual tailored exercise recommendations from the sports therapist. The main outcome was the using behavior, which was obtained by investigating the log-in rate and duration. RESULTS A total of 20 participants (5 from each trial) were analyzed. During the intervention period, a regular contact and a consequent implementation of exercise prescription were easily achieved in all substudies. Across the 4 substudies, there was a significant decrease in log-in rates (P<.001) and log-in durations (P<.001) over time. A detailed view of the different studies shows a significant decrease in log-in rates and log-in durations in the HELP study (P=.004; P=.002) and iPEP study (P=.02; P=.001), whereas the EXDEP study (P=.58; P=.38) and COMMED study (P=.87; P=.56) showed no significant change over the 8-week intervention period. There was no significant change in physical activity within all studies (P=.31). Only in the HELP study, the physical activity level increased steadily over the period analyzed (P=.045). Overall, 17 participants (85%, 17/20) felt secure and were not scared of injury, with no major differences in the subtrials. CONCLUSIONS The universal use of the Web-based intervention appears to be applicable across the heterogonous collectives of our study patients with regard to age and disease. Although the development of physical activity shows only moderate improvements, flexible communication and tailored support could be easily integrated into patients’ daily routine. CLINICALTRIAL iPEP study: ClinicalTrials.gov NCT02478996; https://clinicaltrials.gov/ct2/show/NCT02478996 (Archived by WebCite at http://www.webcitation.org/6zL1UmHaW); HELP study: ClinicalTrials.gov NCT02526732; http://www.webcitation.org/6zJjX7d6K (Archived by WebCite at http://www.webcitation.org/6Nch4ldcL); EXDEP study: ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/6zJjj7FuA)

Coronaphobia and physical activity level in patients with non-cystic fibrosis bronchiectasis during COVID-19 pandemic

2021 ◽  
Author(s):  
Merve Firat ◽  
Naciye Vardar-Yagli ◽  
Aslihan Cakmak ◽  
Melda Saglam ◽  
Ebru Calik-Kutukcu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Physical Activity Level ◽  
Activity Level

scholarly journals Successful promotion of physical activity among students of medicine through motivational interview and Web-based intervention

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e9495 ◽  
Author(s):  
Dubravka Mandic ◽  
Vesna Bjegovic-Mikanovic ◽  
Dejana Vukovic ◽  
Bosiljka Djikanovic ◽  
Zeljka Stamenkovic ◽  
...  
Keyword(s):  
Physical Activity ◽  
Social Media ◽  
Logistic Regression ◽  
Motivational Interview ◽  
Statistical Testing ◽  
Intervention Period ◽  
Web Based ◽  
Low Level ◽  
One Year ◽  
Multicomponent Interventions

Background Regular physical activity supports healthy behavior and contributes to the reduction of preventable diseases. Students in their social transition period are the ideal groups for interventions. The higher education period, associated with demanding changes and poor time management, results in a low level of physical activity. In this age, social media usually are a suitable channel of communication and multicomponent interventions are the most desirable. It has not been sufficiently investigated how effective a Web-based approach is among university students when it comes to physical activity in the long-term period. We combined a Web-based approach with motivational interviews and tested these two interventions together and separate to assess their impact on improving the physical activity of medical students 1 year after the intervention. Methods All 514 first-year students at the Faculty of Medicine in Belgrade were invited to fill in a baseline questionnaire. Also, they underwent measurement of weight, height and waist circumference. After that, students selected a 6 months intervention according to their preference: Intervention through social media (Facebook) (Group 1) or combined with a motivational interview (Group 2). Group 3 consisted of students without any intervention. One year after completion of the 6 months intervention period, all students were invited to a second comprehensive assessment. Analyses were performed employing a wide range of statistical testing, including direct logistic regression, to identify determinants of increased physical activity measured by an average change of Metabolic Equivalent of Task (MET). This outcome measure was defined as the difference between the values at baseline and one year after completion of the 6 months intervention period. Results Due to a large number of potential determinants of the change of MET, three logistic regression models considered three groups of independent variables: basic socio-demographic and anthropometric data, intervention and willingness for change, and health status with life choices. The only significant model comprised parameters related to the interventions (p < 0.001). It accurately classified 73.5% of cases. There is a highly significant overall effect for type of intervention (Wald = 19.5, df = 2, p < 0.001) with high odds for the increase of physical activity. Significant relationship between time and type of intervention also existed (F = 7.33, p < 0.001, partial η2 = 0.091). The influence of both factors (time and interventions) led to a change (increase) in the dependent variable MET. Conclusion Our study confirmed the presence of low-level physical activity among students of medicine and showed that multicomponent interventions have significant potential for positive change. The desirable effects of the Web-based intervention are higher if an additional booster is involved, such as a motivational interview.

scholarly journals Physical Activity Level and Perception of Exercise in Cystic Fibrosis

2020 ◽  
Vol 65 (4) ◽  
pp. 500-506 ◽  
Author(s):  
David M Burnett ◽  
Ashley N Barry ◽  
Joel D Mermis
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Physical Activity Level ◽  
Activity Level

scholarly journals A web-based intervention to promote physical activity in adolescents and young adults with cystic fibrosis: protocol for a randomized controlled trial

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Narelle S. Cox ◽  
◽  
Beverley Eldridge ◽  
Sarah Rawlings ◽  
Julianna Dreger ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Randomized Controlled Trial ◽  
Young Adults ◽  
Controlled Trial ◽  
Adolescents And Young Adults ◽  
Physical Activity Participation ◽  
Activity Participation ◽  
Web Based ◽  
Randomized Controlled

Abstract Background Regular participation in physical activity by people with cystic fibrosis (CF) promotes positive clinical and health outcomes including reduced rate of decline in lung function, fewer hospitalizations and greater wellbeing. However adherence to exercise and activity programs is low, in part due to the substantial daily therapy burden for young people with CF. Strict infection control requirements limit the role of group exercise programs that are commonly used in other clinical groups. Investigation of methods to promote physical activity in this group has been limited. The Active Online Physical Activity in Cystic fibrosis Trial (ActionPACT) is an assessor-blinded, multi-centre, randomized controlled trial designed to compare the efficacy of a novel web-based program (ActivOnline) compared to usual care in promoting physical activity participation in adolescents and young adults with CF. Methods Adolescents and young adults with CF will be recruited on discharge from hospital for a respiratory exacerbation. Participants randomized to the intervention group will have access to a web-based physical activity platform for the 12-week intervention period. ActivOnline allows users to track their physical activity, set goals, and self-monitor progress. All participants in both groups will be provided with standardised information regarding general physical activity recommendations for adolescents and young adults. Outcomes will be assessed by a blinded assessor at baseline, after completion of the intervention, and at 3-months followup. Healthcare utilization will be assessed at 12 months from intervention completion. The primary outcome is change in moderate-to-vigorous physical activity participation measured objectively by accelerometry. Secondary outcomes include aerobic fitness, health-related quality of life, anxiety and depression and sleep quality. Discussion This trial will establish whether a web-based application can improve physical activity participation more effectively than usual care in the period following hospitalization for a respiratory exacerbation. The web-based application under investigation can be made readily and widely available to all individuals with CF, to support physical activity and exercise participation at a time and location of the user’s choosing, regardless of microbiological status. Trial registration Clinical trial registered on July 13, 2017 with the Australian and New Zealand Clinical Trials Register at (ACTRN12617001009303).

scholarly journals Do health care physician need to risk their own lives? Time to change our own attitude towards recommended physical activity

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
S Memon ◽  
S Khowaja ◽  
A Shaikh ◽  
S Memon ◽  
K Bhatti ◽  
...  
Keyword(s):  
Physical Activity ◽  
Health Care ◽  
Primary Prevention ◽  
Physical Activity Level ◽  
Activity Level ◽  
Moderate Intensity ◽  
Public Healthcare ◽  
Daily Routine ◽  
Point Scale ◽  
Recommended Physical Activity

Abstract Background Cardiovascular diseases are the leading cause of death around the world,South Asian population are at higher risk of atherosclerotic coronary artery diseases (CAD) comparatively. There is a recommended physical activity level to prevent atherosclerotic cardiovascular disease (ASCVD). Health care professionals especially doctors are main advisors to prescribe the exercise protocols among general population. Hence we conducted a survey among doctors of Pakistan to identify their physical activity as well as their knowledge and attitude toward recommended physical activity. Methodology An online questionnaire was shared with doctors of various specialties working in private and public healthcare system of the Pakistan. It consisted of consent for participation,followed by information regarding demographic profile, preexisting co-morbid conditions, opinion regarding importance of physical activity to prevent ASCVD (5 point scale), perceived physical activity level (4 point scale), knowledge regarding ACC recommended physical activity level for primary prevention of ASCVD, lifestyle, and barriers in following recommended physical activity level. Collected data were entered and analyzed using SPSS version 21.0, participants were categorized into two groups as “cardiologists” and “non-cardiologists” and results were compared between the two groups. Results A total of 159 doctors participated in the survey, out of whom 97 (61%) were cardiologist and remaining 62 (39%) were affiliated with other specialties. Male participants (72.3%) were predominant and mean age was 30.44±23.16 years. More than 60% (61.6%) of the participants were free of preexisting co-morbid condition, most common ASCVD risk factor was positive family history (26.4%) followed by smoking (7.5%) and hypertension (6.3%). According to BMI, 21.4% (34) were obese and 40.3% (64) were overweight. A total of 74.8% (119) of the participants claimed to know about ACC recommended physical activity level but 65.5% (78) were actually aware of recommended 150 min of moderate-intensity or 75 min of vigorous-intensity aerobic activity level. According to the lifestyle activities only 26.4% (42) of the participants were found to follow the ACC recommended physical activity level per week, this proportion was same between cardiologists and non-cardiologists, 25.8% vs. 27.4% respectively. Lack of time from daily routine (71.7%) was found to be most commonly stated reason for physical in activeness followed by overburden/over stress at workplace (33.3%) and lack of resources (14.5%). Conclusion Knowledge and adherence to the ACC recommended physical actively level was poor among both cardiologists and non-cardiologists even after considering it important for the primary prevention of ASCVD. Majority of doctors were overweight and obese.Lake of time and resources and over stressed work life of doctors are the key barriers in following recommended physical activity level. FUNDunding Acknowledgement Type of funding sources: None.

Clinical validation of digital biomarkers for pediatric patients with asthma and cystic fibrosis - Potential for clinical trials and clinical care

2021 ◽  
pp. 2100208
Author(s):  
Matthijs D. Kruizinga ◽  
Esmée Essers ◽  
Frederik E. Stuurman ◽  
Yalçin Yavuz ◽  
Marieke L. de Kam ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Heart Rate ◽  
Clinical Trials ◽  
Clinical Care ◽  
Clinical Validation ◽  
Healthy Children ◽  
Children With Asthma ◽  
Digital Biomarkers ◽  
Lower Physical Activity

BackgroundDigital biomarkers are a promising novel method to capture clinical data in a home-setting. However, clinical validation prior to implementation is of vital importance. The aim of this study was to clinically validate physical activity, heart rate, sleep and FEV1 as digital biomarkers measured by a smartwatch and portable spirometer in children with asthma and cystic fibrosis (CF).MethodsThis was a prospective cohort study including 60 children with asthma and 30 children with CF (age 6–16). Participants wore a smartwatch, performed daily spirometry at home and completed a daily symptom questionnaire for 28-days. Physical activity, heart rate, sleep and FEV1 were considered candidate digital endpoints. Data from 128 healthy children was used for comparison. Reported outcomes were compliance, difference between patients and controls, correlation with disease-activity and potential to detect clinical events. Analysis was performed with linear mixed effect models.ResultsMedian compliance was 88%. On average, patients exhibited lower physical activity and FEV1 compared to healthy children, whereas the heart rate of children with asthma was higher compared to healthy children. Days with a higher symptom score were associated with lower physical activity for children with uncontrolled asthma and CF. Furthermore, FEV1 was lower and (nocturnal) heart rate was higher for both patient groups on days with more symptoms. Candidate biomarkers and showed a distinct pattern before- and after a pulmonary exacerbation.ConclusionPortable spirometer- and smartwatch-derived digital biomarkers show promise as candidate endpoints for use in clinical trials or clinical care in pediatric lung disease.

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