P1.04. Hyalinizing clear cell carcinoma of salivary glands: Experiencein the National Institute of Cancer of México

2009 ◽  
Vol 3 (1) ◽  
pp. 124
Author(s):  
J. Soriano ◽  
A.M. Cano
2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Takahiro Yamanishi ◽  
Kiwako Kutsuma ◽  
Keisuke Masuyama

Hyalinizing clear cell carcinoma (HCCC), so-called clear cell carcinoma, not otherwise specified (CCC (NOS)), of the salivary glands is a rare and low-grade malignant tumor. We report a case of HCCC so-called CCC (NOS) (referred to as HCCC) of the minor salivary gland of the buccal mucosa. A 52-year-old woman had presented with a gradually growing and indolent mass in the right buccal mucosa for about two years. The first biopsy histopathologically suggested the possibility of malignancy derived from the minor salivary glands. A month later, she visited our hospital. The tumor measured approximately 1.5 cm in diameter and was elastic hard, smooth, and well movable. Image examinations demonstrated internal homogeneity of the lesion, which had a smooth margin, in the right buccal mucosa. Complete tumor resection followed by covering with a polyglycolic acid sheet and fibrin glue spray was performed without surgical flap reconstruction. Histopathological findings revealed proliferating tumor cells with clear cytoplasm surrounded by hyalinizing stroma in the submucosal minor salivary glands. Immunohistochemical stains revealed these tumor cells to be positive for epithelial cell markers but negative for myoepithelial ones. These findings confirmed the diagnosis of HCCC. Good wound healing and no evidence of local recurrence and metastasis have been shown since surgery.


2021 ◽  
pp. 171-175

Hyalinizing clear cell carcinoma (HCCC) usually affects minor salivary glands. It rarely occurs in major salivary glands. HCCCis difficult to diagnose in Fine Needle Aspiration cytology (FNAC). The possibility of metastasis from other primary sites should be rejected during the management of these tumors. An elderly manpresented with insidious onset, and gradual progressive painless swelling arising from the deep lobe of the parotid gland. FNAC, which was performedtwice with UltrasoundGuidance(USG), could not provide much detail about the type of tumor. Total conservative parotidectomy was conducted. These rare tumors cause significant challenges to physicians. Thehigh index of suspicion and combined efforts ofthe multidisciplinary team are pivotal in management.


2002 ◽  
Vol 116 (10) ◽  
pp. 851-853 ◽  
Author(s):  
R. Balakrishnan ◽  
Dipak Ranjan Nayak ◽  
Suresh Pillai ◽  
Lakshmi Rao

Clear cell carcinoma of the salivary glands is a rare tumour that represents less than one per cent of all salivary tumours. They are divided into a biphasic, epithelial-myoepithelial carcinoma and a monophasic pattern which may be myoepithelial or ductal in origin. The latter is accompanied by prominent fibrohyaline stroma and has been described recently as hyalinizing clear cell carcinoma (HCCC).Most of the HCCC occur in the oral cavity, and are associated with minor salivary glands, unlike the biphasic pattern which is more common in the major salivary glands. In the oral cavity, the commonest site is the palate followed by the lips and the buccal mucosa. Its occurrence in the oropharynx and the larynx is extremely rare.


2000 ◽  
Vol 23 (5) ◽  
pp. 333-337 ◽  
Author(s):  
Sara Milchgrub ◽  
Frank Vuitch ◽  
M. Hossein Saboorian ◽  
Arif Hameed ◽  
Horace Wu ◽  
...  

2005 ◽  
Vol 41 (10) ◽  
pp. 306-310 ◽  
Author(s):  
Zhi-Jun Sun ◽  
Yi-Fang Zhao ◽  
Lu Zhang ◽  
Wen-Feng Zhang ◽  
Xin-Ming Chen ◽  
...  

Oral Oncology ◽  
2002 ◽  
Vol 38 (4) ◽  
pp. 364-368 ◽  
Author(s):  
Ana Félix ◽  
Joaninha Costa Rosa ◽  
José F Moura Nunes ◽  
Isabel Fonseca ◽  
António Cidadão ◽  
...  

2015 ◽  
Vol 129 (S2) ◽  
pp. S95-S97 ◽  
Author(s):  
T Nakashima ◽  
R Yasumatsu ◽  
M Yamauchi ◽  
S Toh ◽  
T Nakano ◽  
...  

AbstractBackground:Hyalinizing clear cell carcinoma is a rare minor salivary gland neoplasm. The treatment of choice is surgical resection with or without post-operative radiotherapy. This tumour often demonstrates a good prognosis.Case report:We report a case of hyalinizing clear cell carcinoma arising in the nasopharynx. A 27-year-old female presented with progressive hearing disturbance and tinnitus. On examination, an expansile mass was observed in her nasopharynx. Biopsy was performed and the pathology results returned as clear cell carcinoma.Results and conclusion:Surgical resection was performed trans-orally accompanied by trans-palatal approach. She has no recurrence during more than two years of follow up.


1994 ◽  
Vol 18 (1) ◽  
pp. 74-82 ◽  
Author(s):  
Sara Milchgrub ◽  
Douglas R. Gnepp ◽  
Frank Vuitch ◽  
Ruby Delgado ◽  
Jorge Albores-Saavedra

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