Kaposi Sarcoma in an HIV-Negative Patient

2018 ◽  
Vol 126 (3) ◽  
pp. e45
Author(s):  
Aline Fernanda Cruz ◽  
José Augusto Dias Araújo ◽  
Samuel Macedo Costa ◽  
Júlio César Tanos De Lacerda ◽  
Patrícia Carlos Caldeira ◽  
...  
Keyword(s):  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Hiv Negative

Tonsillar Kaposi sarcoma in an HIV-negative patient

AIDS ◽  
2019 ◽  
Vol 33 (7) ◽  
pp. 1263-1264 ◽  
Author(s):  
Alessandra Latini ◽  
Lavinia Alei ◽  
Renato Covello ◽  
Antonio Cristaudo ◽  
Manuela Colafigli ◽  
...  
Keyword(s):  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Hiv Negative

A Case of Kaposi’s Sarcoma in a HIV Negative Patient with CLL Treated with Rituximab

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 4970-4970
Author(s):  
Anuradha Avinash Belur ◽  
Arun Kumar Arumugam Raajasekar ◽  
Srikant Nannapaneni ◽  
Thandavababu Chelliah
Keyword(s):  
Kaposi's Sarcoma ◽  
Conflicts Of Interest ◽  
Kaposi Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Skin Lesions ◽  
Elisa Test ◽  
Lymphocytic Leukemia ◽  
Cell Mediated Immunity ◽  
Negative Patient ◽  
Hiv Negative

Abstract Case Description: - A 76 year old lady was diagnosed with Chronic Lymphocytic Leukemia (CLL) with 11 q deletion after she presented with generalized lymphadenopathy and anemia. She was treated with rituximab 375mg/m2 day1 and bendamustine 60mg/m2 on day 1 and day 2 and completed six cycles of treatment. After the sixth cycle she developed multiple itchy, papular lesions with bleeding on both lower extremities. She was evaluated multiple times by vascular surgery and dermatology without a definitive diagnosis. She underwent a biopsy with staining for HHV-8, CD31 and CD34 which was positive confirming the diagnosis of Kaposi sarcoma. ELISA test for HIV was negative. She was started on treatment with Doxorubicin 20 mg/m2every 3 weeks and with 3 cycles there was significant regression of the lesions. Discussion-: We describe a case of CLL which was initially started on treatment with rituximab and bendamustine. She tolerated the treatment well, but a few months later presented with skin lesions which on biopsy was diagnosed as Kaposi sarcoma. It is very uncommon for Kaposi sarcoma to develop in a HIV negative patient. This patient was immunocompromised with recent chemotherapy. Rituximab specifically depletes B cells and leads to impaired T cell mediated immunity. This case illustrates the importance of a high index of suspicion in patients treated with rituximab as it is used for a number of hematologic malignancies like leukemia, lymphoma as well as non-malignant conditions like autoimmune disorders. While infusion reactions and reactivation of hepatitis B are side effects physicians are aware of and cautious of while using rituximab, Kaposi’s Sarcoma remains a less known side effect. Awareness of this possibility is important in physicians prescribing rituximab. Footnotes * Asterisk with author names denotes non-ASH members. Disclosures No relevant conflicts of interest to declare.

Genetically Determined Coincidence of Kaposi Sarcoma and Psoriasis in an HIV-Negative Patient After Prednisolone Treatment.

1991 ◽  
Vol 30 (2) ◽  
pp. 114-120 ◽  
Author(s):  
Beate Tebbe ◽  
Augusto Mayer-da-Silva ◽  
C. Garbe ◽  
Hans-Joachim Keyserlingk ◽  
Constantin E. Orfanos
Keyword(s):  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Prednisolone Treatment ◽  
Genetically Determined ◽  
Hiv Negative

scholarly journals Eyelid Kaposi Sarcoma in an HIV-negative Patient

2018 ◽  
Vol 66 (6) ◽  
pp. 854 ◽  
Author(s):  
JoseManuel Abalo-Lojo ◽  
Ihab Abdulkader-Nallib ◽  
LauraMartínez Pérez ◽  
Francisco Gonzalez
Keyword(s):  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Hiv Negative

scholarly journals Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Zeliha Esin Celik ◽  
Murat Celik ◽  
Erdem Sen ◽  
Hakan Cebeci ◽  
Ozlem Ata ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Systemic Disease ◽  
Human Herpesvirus ◽  
Kaposi Sarcoma ◽  
Metastatic Potential ◽  
Cutaneous Lesions ◽  
Negative Patient ◽  
First Case ◽  
Anaplastic Transformation ◽  
Hiv Negative

Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anaplastic transformation of KS is a rare clinical presentation known as an aggressive disease with local recurrence and metastatic potential. We report here a 47-year-old HIV negative male presented with extra-adrenal symptoms and had an incidentally detected anaplastic adrenal KS exhibited aggressive clinical course. To the best of our knowledge, this is the first case of anaplastic primary adrenal KS without mucocutaneous involvement but subsequently developed other side adrenal metastases in an HIV negative patient.

Topical timolol for treatment of penile Kaposi sarcoma in HIV-negative patient

2017 ◽  
Vol 30 (5) ◽  
pp. e12519 ◽  
Author(s):  
L. Sainz-Gaspar ◽  
J. M. Suárez-Peñaranda ◽  
M. Pousa-Martínez ◽  
H. Vázquez-Veiga ◽  
V. Fernández-Redondo
Keyword(s):  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Hiv Negative

scholarly journals Primary Kaposi sarcoma of the glans: A rare case in an HIV‐negative patient

2020 ◽  
Vol 8 (7) ◽  
pp. 1134-1137
Author(s):  
Farnaz Araghi ◽  
Mohammadreza Tabary ◽  
Farahnaz Bidari‐Zerehpoosh ◽  
Zahra Asadi‐Kani ◽  
Reza M. Robati
Keyword(s):  
Rare Case ◽  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Hiv Negative

Solitary Eyelid Kaposi Sarcoma in an HIV-Negative Patient

Cornea ◽  
2006 ◽  
Vol 25 (4) ◽  
pp. 490-492 ◽  
Author(s):  
Rosanna Dammacco ◽  
Lucia Lapenna ◽  
Giovanni Giancipoli ◽  
Domenico Piscitelli ◽  
Carlo Sborgia
Keyword(s):  
Kaposi Sarcoma ◽  
Negative Patient ◽  
Hiv Negative
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