Rho-associated kinase in the gustatory cortex is involved in conditioned taste aversion memory formation but not in memory retrieval or relearning

2012 ◽  
Vol 97 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Sahar Sweetat ◽  
Kobi Rosenblum ◽  
Raphael Lamprecht
Keyword(s):  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Memory Retrieval ◽  
Memory Formation ◽  
Gustatory Cortex

scholarly journals Region-Specific Involvement of BDNF Secretion and Synthesis in Conditioned Taste Aversion Memory Formation

2011 ◽  
Vol 31 (6) ◽  
pp. 2079-2090 ◽  
Author(s):  
L. Ma ◽  
D.-D. Wang ◽  
T.-Y. Zhang ◽  
H. Yu ◽  
Y. Wang ◽  
...  
Keyword(s):  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Memory Formation

Altered gene activity correlated with long-term memory formation of conditioned taste aversion inLymnaea

2006 ◽  
Vol 84 (7) ◽  
pp. 1610-1620 ◽  
Author(s):  
Sachiyo Azami ◽  
Akiko Wagatsuma ◽  
Hisayo Sadamoto ◽  
Dai Hatakeyama ◽  
Takeshi Usami ◽  
...  
Keyword(s):  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Memory Formation ◽  
Gene Activity ◽  
Long Term Memory ◽  
Term Memory ◽  
Altered Gene

scholarly journals Gene Network Analysis in Amygdala following Taste Aversion Learning in Rats

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Siva K. Panguluri ◽  
Nobuyuki Kuwabara ◽  
Nigel Cooper ◽  
Srinivas M. Tipparaju ◽  
Kevin B. Sneed ◽  
...  
Keyword(s):  
Gene Expression ◽  
Taste Aversion ◽  
Differentially Expressed Genes ◽  
Conditioned Taste Aversion ◽  
In Silico ◽  
Regulation Of Gene Expression ◽  
Memory Formation ◽  
Nervous System Development ◽  
Differentially Expressed ◽  
Taste Aversion Learning

Conditioned taste aversion (CTA) is an adaptive behavior that benefits survival of animals including humans and also serves as a powerful model to study the neural mechanisms of learning. Memory formation is a necessary component of CTA learning and involves neural processing and regulation of gene expression in the amygdala. Many studies have been focused on the identification of intracellular signaling cascades involved in CTA, but not late responsive genes underlying the long-lasting behavioral plasticity. In this study, we explored in silico experiments to identify persistent changes in gene expression associated with CTA in rats. We used oligonucleotide microarrays to identify 248 genes in the amygdala regulated by CTA. Pathway Studio and IPA software analyses showed that the differentially expressed genes in the amygdala fall in diverse functional categories such as behavior, psychological disorders, nervous system development and function, and cell-to-cell signaling. Conditioned taste aversion is a complex behavioral trait which involves association of visceral and taste inputs, consolidation of taste and visceral information, memory formation, retrieval of stored information, and extinction phase. In silico analysis of differentially expressed genes is therefore necessary to manipulate specific phase/stage of CTA to understand the molecular insight.

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