Method development and validation for the simultaneous determination of cetirizine dihydrochloride, paracetamol, and phenylpropanolamine hydrochloride in tablets by capillary zone electrophoresis

2007 ◽  
Vol 43 (3) ◽  
pp. 873-878 ◽  
Author(s):  
S. Azhagvuel ◽  
R. Sekar
Keyword(s):  
Simultaneous Determination ◽  
Capillary Zone Electrophoresis ◽  
Method Development ◽  
Phenylpropanolamine Hydrochloride ◽  
Zone Electrophoresis ◽  
Method Development And Validation ◽  
Capillary Zone ◽  
Development And Validation

scholarly journals Method Development and Validation for the Simultaneous Determination of Four Coumarins in Saussurea superba by Capillary Zone Electrophoresis

2010 ◽  
Vol 93 (5) ◽  
pp. 1410-1415 ◽  
Author(s):  
Juan Chen ◽  
Li Chen ◽  
Hong-Li Zhang ◽  
Yan-Ping Shi
Keyword(s):  
Simultaneous Determination ◽  
Applied Voltage ◽  
Method Development ◽  
Migration Behavior ◽  
Electrophoretic Method ◽  
Wide Range ◽  
Method Development And Validation ◽  
Capillary Zone ◽  
Development And Validation

Abstract A capillary zone electrophoretic method has been developed for the determination of four coumarinsskimmin, scopolin, scopoletin, and umbelliferonein Saussurea superba with UV detection at 254 nm. The capillary temperature was kept constant at 25°C. Effects of buffer pH, electrolyte concentration, organic modifier, and applied voltage on migration behavior were studied systematically. The optimum conditions for separation were achieved by using 30 mM borate buffer at pH 9.02 containing 15% (v/v) methanol as the electrolyte and 25 kV as the applied voltage. For all analytes a good linear regression relationship (r >0.999) was obtained between peak area and concentration over a relatively wide range. The method was validated for repeatability, precision, and accuracy. The validated method was successfully applied to the simultaneous determination of the four analytes in S. superba.

Sub-minute method for simultaneous determination of aspartame, cyclamate, acesulfame-K and saccharin in food and pharmaceutical samples by capillary zone electrophoresis

2015 ◽  
Vol 1396 ◽  
pp. 148-152 ◽  
Author(s):  
Jacqueline Pereira Vistuba ◽  
Maressa Danielli Dolzan ◽  
Luciano Vitali ◽  
Marcone Augusto Leal de Oliveira ◽  
Gustavo Amadeu Micke
Keyword(s):  
Simultaneous Determination ◽  
Capillary Zone Electrophoresis ◽  
Pharmaceutical Samples ◽  
Zone Electrophoresis ◽  
Capillary Zone
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